24-ethyl-4-cholesten-3-one and isocitric-acid

A new drimane-type sesquiterpene with an isocitric acid moiety, cryptoporic acid S (1), together with six known compounds, cryptoporic acid D (2), β-sitosterol (3), β-daucosterol (4), stigmast-4-en-3-one (5), ergosterol (6), and (22E,24R)-ergosta-7,22-diene-3β,5α,6β-triol (7), was isolated from the fruiting bodies of Cryptoporus volvatus. The structures of these compounds were established on the basis of UV, IR, MS, 1D and 2D NMR analysis. In the meanwhile, compounds 1 and 2 were evaluated for antioxidant activity using the methods of 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity (DPPH-RSA) and ferric reducing antioxidant power (FRAP) assay, and they exhibited moderate antioxidant activities.

Topics: Antioxidants; Biphenyl Compounds; China; Coriolaceae; Ergosterol; Ethers; Fruiting Bodies, Fungal; Isocitrates; Molecular Structure; Picrates; Polycyclic Sesquiterpenes; Sesquiterpenes; Sitosterols; Stigmasterol