Page last updated: 2024-09-03

24,25-epoxycholesterol and 25-hydroxycholesterol

24,25-epoxycholesterol has been researched along with 25-hydroxycholesterol in 8 studies

Compound Research Comparison

Studies (24,25-epoxycholesterol)	Trials (24,25-epoxycholesterol)	Recent Studies (post-2010) (24,25-epoxycholesterol)	Studies (25-hydroxycholesterol)	Trials (25-hydroxycholesterol)	Recent Studies (post-2010) (25-hydroxycholesterol)
65	0	18	853	3	243

Protein Interaction Comparison

Protein	Taxonomy	24,25-epoxycholesterol (IC50)	25-hydroxycholesterol (IC50)
3-hydroxy-3-methylglutaryl-coenzyme A reductase	Homo sapiens (human)		0.3
Sterol regulatory element-binding protein 2	Homo sapiens (human)		0.3

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (37.50)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (62.50)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bledsoe, RK; Collins, JL; Consler, TG; Galardi, CM; Lambert, MH; Li, D; McKee, DD; Moore, JT; Moore, LB; Parks, DJ; Russel, JS; Spencer, TA; Watson, MA; Willson, TM	1
Gayen, AK; Logel, J; Phirwa, S; Sinensky, M; Spencer, TA	1
Gayen, AK; Kandutsch, AA; Phirwa, S; Saucier, SE; Spencer, TA; Taylor, FR	1
Li, D; Spencer, TA	1
Blanchard, DE; Erickson, SK; Lear, SR; Li, D; Spencer, TA; Zhang, Z	1
Ai, N; Ekins, S; Hagey, LR; Krasowski, MD; Reschly, EJ; Welsh, WJ	1
Kim, YS; Trasino, SE; Wang, TT	1

Reviews

1 review(s) available for 24,25-epoxycholesterol and 25-hydroxycholesterol

Article	Year
Progesterone effects on sterol biosynthesis. Nutrition reviews, 1988, Volume: 46, Issue:8 Topics: Animals; Cholesterol; Hydroxycholesterols; Progesterone; Rats	1988

Other Studies

7 other study(ies) available for 24,25-epoxycholesterol and 25-hydroxycholesterol

Article	Year
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Cell Line; Cell Nucleus; Cell-Free System; Chlorocebus aethiops; Cholesterol; Cholic Acids; DNA-Binding Proteins; Energy Transfer; Fluorescence; Histone Acetyltransferases; Hydroxycholesterols; Ketocholesterols; Liver X Receptors; Models, Molecular; Molecular Sequence Data; Nuclear Receptor Coactivator 1; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Stereoisomerism; Sterols; Structure-Activity Relationship; Transcription Factors; Tryptophan	2001
Requirement for 24(S),25-epoxycholesterol for the viability of cultured fibroblasts. Experimental cell research, 1987, Volume: 171, Issue:2 Topics: Animals; Cell Line; Cell Survival; Cholesterol; Cricetinae; Fibroblasts; Hydroxycholesterols; Mevalonic Acid	1987
Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts. The Journal of biological chemistry, 1985, Nov-25, Volume: 260, Issue:27 Topics: Animals; Cattle; Cell Line; Cholesterol; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cricetinae; Cricetulus; Culture Media; Enzyme Repression; Fetus; Fibroblasts; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Lung; Mevalonic Acid; Tritium	1985
Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols. Steroids, 2000, Volume: 65, Issue:9 Topics: Bile Acids and Salts; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Humans; Hydroxycholesterols; Stereoisomerism	2000
Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations. Journal of lipid research, 2001, Volume: 42, Issue:4 Topics: Animals; Cholesterol; Cholesterol Oxidase; Chromatography, High Pressure Liquid; Diet, Atherogenic; Hydroxycholesterols; Ketones; Liver; Male; Mevalonic Acid; Molecular Structure; Rats; Rats, Inbred F344; Tissue Extracts	2001
Ligand specificity and evolution of liver X receptors. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 110, Issue:1-2 Topics: Androstenes; Animals; Benzoates; Benzylamines; Carbazoles; Cell Line, Tumor; Cholesterol; Ciona intestinalis; DNA-Binding Proteins; Evolution, Molecular; Humans; Hydrocarbons, Fluorinated; Hydroxycholesterols; Liver X Receptors; Mice; Molecular Structure; Orphan Nuclear Receptors; Phylogeny; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship; Sulfonamides; Xenopus laevis; Zebrafish	2008
Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells. Molecular cancer therapeutics, 2009, Volume: 8, Issue:7 Topics: ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cholesterol; DNA-Binding Proteins; Humans; Hydrocarbons, Fluorinated; Hydroxycholesterols; Ligands; Liver X Receptors; Male; Neoplasms, Hormone-Dependent; Orphan Nuclear Receptors; Prostatic Neoplasms; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured	2009