Page last updated: 2024-09-03

20-hydroxy-5,8,11,14-eicosatetraenoic acid and serine

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with serine in 4 studies

Compound Research Comparison

Studies
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Trials
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Recent Studies (post-2010)
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Studies
(serine)
Trials
(serine)
Recent Studies (post-2010) (serine)
6401323323,9141156,084

Protein Interaction Comparison

ProteinTaxonomy20-hydroxy-5,8,11,14-eicosatetraenoic acid (IC50)serine (IC50)
AcetylcholinesteraseElectrophorus electricus (electric eel)0.015
CholinesteraseEquus caballus (horse)0.016

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, Y; Falck, JR; Jacobs, ER; Medhora, M; Pritchard, KA1
Ahluwalia, A; Baker, MD; Bubb, KJ; Östman, J; Panayiotou, C; Priestley, JV; Wen, H1
Hong, J; Li, R; Li, X; Liu, S; Ma, B; Wang, DW; Zhao, G1
Abraham, NG; Canestraro, M; Cao, J; Lee, CR; Schwartzman, ML; Vanella, L; Zeldin, DC1

Other Studies

4 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and serine

ArticleYear
Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 291, Issue:3

    Topics: Animals; Cattle; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Enzyme Activation; HSP90 Heat-Shock Proteins; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Serine; Vascular Endothelial Growth Factor A

2006
20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel.
    The Journal of biological chemistry, 2012, Apr-20, Volume: 287, Issue:17

    Topics: Animals; Arachidonic Acid; Capsaicin; Female; Ganglia, Spinal; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neurons; Patch-Clamp Techniques; Serine; TRPV Cation Channels

2012
20-Hydroxyeicosatetraenoic acid impairs endothelial insulin signaling by inducing phosphorylation of the insulin receptor substrate-1 at Ser616.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Animals; Aorta; Cardiovascular Agents; Cardiovascular Diseases; Cells, Cultured; Drug Evaluation, Preclinical; Extracellular Signal-Regulated MAP Kinases; Human Umbilical Vein Endothelial Cells; Humans; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Receptor Substrate Proteins; MAP Kinase Signaling System; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Serine

2014
Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasis.
    Prostaglandins & other lipid mediators, 2015, Volume: 120

    Topics: Animals; Blood Vessels; Body Weight; Cytokines; Eicosanoids; Epoxide Hydrolases; Female; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Homeostasis; Hydroxyeicosatetraenoic Acids; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Serine; Sex Characteristics; Solubility; Superoxides; Threonine

2015