Page last updated: 2024-09-03

20-hydroxy-5,8,11,14-eicosatetraenoic acid and cyclic gmp

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with cyclic gmp in 4 studies

Compound Research Comparison

Studies
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Trials
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Recent Studies (post-2010)
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Studies
(cyclic gmp)
Trials
(cyclic gmp)
Recent Studies (post-2010) (cyclic gmp)
6401323322,3463334,062

Protein Interaction Comparison

ProteinTaxonomy20-hydroxy-5,8,11,14-eicosatetraenoic acid (IC50)cyclic gmp (IC50)
Phosphodiesterase Bos taurus (cattle)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.4

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Falcone, JC; Grider, JS; Jackson, BA; Kilpatrick, EL; Ott, CE1
Alonso-Galicia, M; Falck, JR; Harder, DR; Roman, RJ; Sun, CW1
Alonso-Galicia, M; Harder, DR; Hudetz, AG; Roman, RJ; Shen, H1
Falck, JR; Harder, DR; Okamoto, H; Roman, RJ; Sun, CW1

Other Studies

4 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and cyclic gmp

ArticleYear
P450 arachidonate metabolites mediate bradykinin-dependent inhibition of NaCl transport in the rat thick ascending limb.
    Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Bradykinin; Calcium; Cyclic GMP; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney Tubules, Distal; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride

1997
Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteries.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Alkaloids; Animals; Arterioles; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Guanylate Cyclase; Hydroxyeicosatetraenoic Acids; Indoles; Male; Nitric Oxide; Nitroprusside; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Renal Artery; Vasoconstrictor Agents; Vasodilation

1998
Contribution of 20-HETE to vasodilator actions of nitric oxide in the cerebral microcirculation.
    Stroke, 1999, Volume: 30, Issue:12

    Topics: Adenosine; Alkaloids; Amides; Animals; Basilar Artery; Carbazoles; Cerebrovascular Circulation; Cyclic GMP; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; Hydroxyeicosatetraenoic Acids; Indoles; Male; Microcirculation; Middle Cerebral Artery; Mixed Function Oxygenases; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sulfones; Vasodilation; Vasodilator Agents

1999
Role of cGMP versus 20-HETE in the vasodilator response to nitric oxide in rat cerebral arteries.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:1

    Topics: Animals; Cerebral Arteries; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Patch-Clamp Techniques; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents

2000