Page last updated: 2024-09-03

20-hydroxy-5,8,11,14-eicosatetraenoic acid and carbachol

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with carbachol in 4 studies

Compound Research Comparison

Studies
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Trials
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Recent Studies (post-2010)
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Studies
(carbachol)
Trials
(carbachol)
Recent Studies (post-2010) (carbachol)
6401323313,91881968

Protein Interaction Comparison

ProteinTaxonomy20-hydroxy-5,8,11,14-eicosatetraenoic acid (IC50)carbachol (IC50)
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.7849
Muscarinic acetylcholine receptor M4Homo sapiens (human)2.0626
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)3.4134
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)2.9961
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)2.535
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)2.9961
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)2.6638
Muscarinic acetylcholine receptor M1Homo sapiens (human)4.849
Muscarinic acetylcholine receptor M3Homo sapiens (human)4.99

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akhtar, S; Benter, IF; Dahly-Vernon, AJ; Dunn, KM; Roman, RJ; Yousif, MH1
Hai, L; Henriksen, FH; Inoue, R; Ito, Y; Jensen, LJ; Jian, Z; Kawarabayashi, Y; Lurie, AI; Mori, M; Mori, Y; Morita, H; Salomonsson, M; Shi, J1
Blair, IA; Christmas, P; Cooper, PR; Douaidy, K; Mesaros, AC; Mittelman, MA; Panettieri, RA; Soberman, RJ; Stark, CM; Zhang, J1
Benter, IF; Yousif, MH1

Other Studies

4 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and carbachol

ArticleYear
Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes.
    Autonomic & autacoid pharmacology, 2009, Volume: 29, Issue:1-2

    Topics: Amidines; Angiotensin II; Animals; Blood Glucose; Body Weight; Carbachol; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Histamine; Hydroxyeicosatetraenoic Acids; Kidney; Male; Mesenteric Arteries; Microsomes; Nitroprusside; Norepinephrine; Perfusion; Rats; Rats, Wistar; Renal Artery; Triazoles; Vasoconstriction; Vasodilation

2009
Synergistic activation of vascular TRPC6 channel by receptor and mechanical stimulation via phospholipase C/diacylglycerol and phospholipase A2/omega-hydroxylase/20-HETE pathways.
    Circulation research, 2009, Jun-19, Volume: 104, Issue:12

    Topics: Animals; Carbachol; Cell Line; Cholinergic Agonists; Cytochrome P-450 CYP4A; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Hydroxylation; Intercellular Signaling Peptides and Proteins; Male; Mechanotransduction, Cellular; Muscle Cells; Peptides; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Spider Venoms; TRPC Cation Channels; TRPC6 Cation Channel; Type C Phospholipases

2009
20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice.
    PloS one, 2010, Apr-20, Volume: 5, Issue:4

    Topics: Animals; Bronchial Hyperreactivity; Carbachol; Hydroxyeicosatetraenoic Acids; Lipid Peroxidation; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Neutrophils; Ozone; Respiratory Hypersensitivity; Triazoles

2010
Role of 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of vascular function in a model of hypertension and endothelial dysfunction.
    Pharmacology, 2010, Volume: 86, Issue:3

    Topics: Amidines; Animals; Arachidonic Acids; Blood Pressure; Carbachol; Cardiovascular Physiological Phenomena; Carotid Arteries; Endothelial Cells; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Urea; Vascular Diseases; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2010