Page last updated: 2024-09-03

20-hydroxy-5,8,11,14-eicosatetraenoic acid and capsaicin

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with capsaicin in 5 studies

Compound Research Comparison

Studies
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Trials
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Recent Studies (post-2010)
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Studies
(capsaicin)
Trials
(capsaicin)
Recent Studies (post-2010) (capsaicin)
6401323311,2386613,410

Protein Interaction Comparison

ProteinTaxonomy20-hydroxy-5,8,11,14-eicosatetraenoic acid (IC50)capsaicin (IC50)
Transient receptor potential cation channel subfamily V member 1Rattus norvegicus (Norway rat)0.019
Lysine-specific histone demethylase 1AHomo sapiens (human)0.6
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Homo sapiens (human)2.6755
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)0.008

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, Z; Hammock, BD; Hwang, SH; Lee, KS; Li, X; Morisseau, C; Wagner, K; Xu, J; Yang, J1
Ahluwalia, A; Chauhan, S; Davis, C; De Felipe, C; Hunt, S; Kabir, J; Kotsonis, P; Oh, U; Scotland, RS1
Cloutier, M; Morin, C; Proteau, S; Rousseau, E1
Ahluwalia, A; Baker, MD; Bubb, KJ; Östman, J; Panayiotou, C; Priestley, JV; Wen, H1
Chen, L; Gollasch, M; Kaßmann, M; Markó, L; Wu, K; Zhu, Y1

Other Studies

5 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and capsaicin

ArticleYear
Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: Analgesics; Animals; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Pain; Pain Threshold; Rats; Transient Receptor Potential Channels

2017
Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction.
    Circulation research, 2004, Nov-12, Volume: 95, Issue:10

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Capsaicin; Cation Transport Proteins; CHO Cells; Cricetinae; Endothelium, Vascular; Gadolinium; Ganglia, Sympathetic; Guanethidine; Hydroxyeicosatetraenoic Acids; Ion Channels; Male; Mesenteric Arteries; Mice; Mice, Knockout; Models, Cardiovascular; Models, Neurological; Nerve Fibers, Unmyelinated; Nociceptors; Peptides, Cyclic; Piperidines; Pressure; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Ruthenium Red; Sodium Channel Blockers; Splanchnic Circulation; Stress, Mechanical; Sympathectomy, Chemical; Tetrodotoxin; TRPV Cation Channels; Vascular Resistance; Vasoconstriction

2004
Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Bronchi; Calcium; Calcium Channels; Capsaicin; Cyclohexanones; Cytochrome P-450 CYP4A; Female; Guinea Pigs; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Intracellular Membranes; Lipoprotein Lipase; Male; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Receptors, Drug; Time Factors; Trachea

2005
20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel.
    The Journal of biological chemistry, 2012, Apr-20, Volume: 287, Issue:17

    Topics: Animals; Arachidonic Acid; Capsaicin; Female; Ganglia, Spinal; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neurons; Patch-Clamp Techniques; Serine; TRPV Cation Channels

2012
Role of TRPV1 channels in ischemia/reperfusion-induced acute kidney injury.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Capsaicin; Eicosanoids; Hydroxyeicosatetraenoic Acids; Kidney; Mice; Mice, Inbred C57BL; Reperfusion Injury; TRPV Cation Channels

2014