20-hydroxy-5,8,11,14-eicosatetraenoic acid and bosentan anhydrous

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with bosentan anhydrous in 1 studies

Compound Research Comparison

Studies (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Trials (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Recent Studies (post-2010) (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Studies (bosentan anhydrous)	Trials (bosentan anhydrous)	Recent Studies (post-2010) (bosentan anhydrous)
640	13	233	1,836	215	630

Protein Interaction Comparison

Protein	Taxonomy	bosentan anhydrous (IC50)
Endothelin receptor type B	Rattus norvegicus (Norway rat)	0.095
Endothelin receptor type B	Homo sapiens (human)	0.3044
Endothelin-1 receptor	Homo sapiens (human)	0.2317
Endothelin-1 receptor	Rattus norvegicus (Norway rat)	0.0047
Endothelin-1 receptor	Sus scrofa (pig)	0.0075

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
De Mey, JG; Hilgers, RH	1

Other Studies

1 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and bosentan anhydrous

Article	Year
Myoendothelial coupling in the mesenteric arterial bed; segmental differences and interplay between nitric oxide and endothelin-1. British journal of pharmacology, 2009, Volume: 156, Issue:8 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bosentan; Calcium Channel Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Gap Junctions; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Myography; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Paracrine Communication; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Endothelin; Sulfonamides; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents	2009

Article

Year

Myoendothelial coupling in the mesenteric arterial bed; segmental differences and interplay between nitric oxide and endothelin-1.

British journal of pharmacology, 2009, Volume: 156, Issue:8

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bosentan; Calcium Channel Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Gap Junctions; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Myography; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Paracrine Communication; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Endothelin; Sulfonamides; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents

2009