20-hydroxy-5,8,11,14-eicosatetraenoic acid and angiotensin ii

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with angiotensin ii in 34 studies

Compound Research Comparison

Studies (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Trials (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Recent Studies (post-2010) (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Studies (angiotensin ii)	Trials (angiotensin ii)	Recent Studies (post-2010) (angiotensin ii)
640	13	233	38,152	1,089	7,413

Protein Interaction Comparison

Protein	Taxonomy	angiotensin ii (IC50)
Atrial natriuretic peptide receptor 3	Homo sapiens (human)	0.002
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	0.002
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0018
Type-1 angiotensin II receptor	Homo sapiens (human)	0.0055
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	0.004
Type-2 angiotensin II receptor	Homo sapiens (human)	0.0011

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (11.76)	18.2507
2000's	17 (50.00)	29.6817
2010's	12 (35.29)	24.3611
2020's	1 (2.94)	2.80

Authors

Authors	Studies
Balazy, M; Falck, JR; Lu, M; Reddy, KM; Wang, W; Zhu, Y	1
Amlal, H; Bichara, M; LeGoff, C; Paillard, M; Soleimani, M; Vernimmen, C	1
Benter, IF; Fatima, S; Harper, J; Karzoun, N; Malik, KU; Muthalif, MM; Uddin, MR	1
George, T; Good, DW; Wang, DH	1
Falck, JR; Frisbee, JC; Lombard, JH	1
Escalante, B; López-Sánchez, P; Martínez-Ayala, S; Rios, A; Sánchez-Mendoza, A; Vázquez-Cruz, B	1
Carroll, MA; Croft, KD; McGiff, JC; Sanchez-Mendoza, A	1
Malik, KU; Muthalif, MM; Nishimoto, AT; Parmentier, JH	1
Abe, M; Arima, S; Chiba, Y; Endo, Y; Ito, O; Ito, S; Kohagura, K; Omata, K	1
Alonso-Galicia, M; Cowley, AW; Greene, AS; Maier, KG; Roman, RJ	1
Capparelli, MF; Carroll, MA; Cheng, MK; Doumad, AB; Jiang, H; McGiff, JC	1
Carroll, MA; Escalante, BA; Ferreri, NR; McGiff, JC; Oyekan, AO	1
Brandes, RP; Busse, R; Fleming, I; Hammock, BD; Jung, O; Kim, IH; Schmidt, R; Schweda, F	1
Bohman, Q; Flasch, A; Roman, RJ; Stec, DE; Taylor, M; Vera, T	1
Estes, AM; Jafari, N; Malik, KU; Parmentier, JH; Schaefer, SA; Yaghini, FA; Zhang, C	1
Bolad, I; Delafontaine, P	1
Caron, N; Flamion, B; Imig, JD; Joly, E; Kramp, R; Michel, A; Seqqat, R	1
Boegehold, MA; Falck, JR; Marvar, PJ	1
Arbab, AS; Chen, P; Edwards, PA; Falck, JR; Guo, AM; Roman, RJ; Scicli, AG	1
Coviello, A; de Bruno, MP; Jerez, S; Sierra, L	1
Akhtar, S; Benter, IF; Dahly-Vernon, AJ; Dunn, KM; Roman, RJ; Yousif, MH	1
Certíková Chábová, V; Cervenka, L; Falck, JR; Hammock, BD; Imig, JD; Kompanowska-Jezierska, E; Kopkan, L; Kramer, HJ; Kujal, P; Sadowski, J; Vanecková, I; Vanourková, Z; Vernerová, Z; Walkowska, A	1
Abraham, NG; Cheng, J; Falck, JR; Goli, M; Gotlinger, K; Inoue, K; Schwartzman, ML; Sodhi, K; Wu, CC	1
Barden, A; Beilin, LJ; Croft, KD; Puddey, IB; Tsai, IJ	1
Cheng, J; Ding, Y; Falck, JR; Garcia, V; Ramu, E; Schwartzman, ML; Thakar, K; Wu, CC	1
Davis, DD; Lima, R; Reckelhoff, JF; Yanes, LL	1
Csiszar, A; Deak, F; Gautam, T; Koller, A; Mitschelen, M; Sonntag, WE; Sosnowska, D; Tarantini, S; Toth, P; Tucsek, Z; Ungvari, Z	1
Csiszar, A; Gautam, T; Koller, A; Schwartzman, ML; Sonntag, WE; Sosnowska, D; Toth, P; Tucsek, Z; Ungvari, Z	1
Didion, SP; Falck, JR; Fan, F; Maier, KG; Pabbidi, MR; Roman, RJ; Sun, CW; Williams, JM; Zhuo, J	1
Bernstein, KE; Capdevila, JH; Dakarapu, R; Ding, Y; Falck, JR; Garcia, V; Gotlinger, K; Joseph, G; Schwartzman, ML; Shkolnik, B; Zhang, FF	1
Gu, Y; Han, Y; OʼRourke, ST; Qi, G; Qian, SY; Shen, X; Sun, C; Xuan, C; Yao, F; Zeng, Q; Zhao, H	1
Abraham, NG; Gotlinger, K; Jiang, H; Maher, E; O'Hanlon, K; Peterson, SJ; Shapiro, JI; Singh, SP; Sodhi, K; Vanella, L	1
Hu, G; Ito, O; Kohzuki, M; Miura, T; Muroya, Y; Ogawa, Y; Rong, R; Wang, W	1
Bar, A; Chlopicki, S; Enggaard, C; Hansen, PBL; Jasztal, A; Jensen, B; Kieronska-Rudek, A; Kij, A; Marczyk, B; Mateuszuk, L; Matyjaszczyk-Gwarda, K; Proniewski, B; Przyborowski, K; Tworzydlo, A; Walczak, M	1

Reviews

2 review(s) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and angiotensin ii

Article	Year
Endothelial dysfunction: its role in hypertensive coronary disease. Current opinion in cardiology, 2005, Volume: 20, Issue:4 Topics: Angiotensin II; Antihypertensive Agents; Arginine; Coronary Disease; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Nitric Oxide; Oxidants	2005
Oxidized HDL is a potent inducer of adipogenesis and causes activation of the Ang-II and 20-HETE systems in human obese females. Prostaglandins & other lipid mediators, 2016, Volume: 123 Topics: Adipocytes; Adipogenesis; Adiponectin; Adult; Angiotensin II; Blood Pressure; Body Mass Index; Case-Control Studies; F2-Isoprostanes; Female; Gene Expression Regulation; Heme Oxygenase-1; Humans; Hydroxyeicosatetraenoic Acids; Lipoproteins, LDL; Metabolic Syndrome; Middle Aged; Obesity; Primary Cell Culture; Tumor Necrosis Factor-alpha	2016

Article

Year

Endothelial dysfunction: its role in hypertensive coronary disease.

Current opinion in cardiology, 2005, Volume: 20, Issue:4

Topics: Angiotensin II; Antihypertensive Agents; Arginine; Coronary Disease; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Nitric Oxide; Oxidants

2005

Oxidized HDL is a potent inducer of adipogenesis and causes activation of the Ang-II and 20-HETE systems in human obese females.

Prostaglandins & other lipid mediators, 2016, Volume: 123

Topics: Adipocytes; Adipogenesis; Adiponectin; Adult; Angiotensin II; Blood Pressure; Body Mass Index; Case-Control Studies; F2-Isoprostanes; Female; Gene Expression Regulation; Heme Oxygenase-1; Humans; Hydroxyeicosatetraenoic Acids; Lipoproteins, LDL; Metabolic Syndrome; Middle Aged; Obesity; Primary Cell Culture; Tumor Necrosis Factor-alpha

2016

Other Studies

32 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and angiotensin ii

Article	Year
Effect of angiotensin II on the apical K+ channel in the thick ascending limb of the rat kidney. The Journal of general physiology, 1996, Volume: 108, Issue:6 Topics: Angiotensin II; Animals; Cell Membrane; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Loop of Henle; Naphthalenes; NG-Nitroarginine Methyl Ester; Patch-Clamp Techniques; Penicillamine; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sodium	1996
ANG II controls Na(+)-K+(NH4+)-2Cl- cotransport via 20-HETE and PKC in medullary thick ascending limb. The American journal of physiology, 1998, Volume: 274, Issue:4 Topics: Angiotensin II; Animals; Arachidonic Acid; Carrier Proteins; Hydroxyeicosatetraenoic Acids; Kidney Medulla; Loop of Henle; Male; Osmolar Concentration; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters	1998
20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America, 1998, Oct-13, Volume: 95, Issue:21 Topics: Angiotensin II; Animals; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Activation; Epidermal Growth Factor; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Male; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Rabbits	1998
Angiotensin II inhibits HCO-3 absorption via a cytochrome P-450-dependent pathway in MTAL. The American journal of physiology, 1999, Volume: 276, Issue:5 Topics: 5,8,11,14-Eicosatetraynoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Acid-Base Equilibrium; Angiotensin II; Animals; Benzoquinones; Bicarbonates; Cyclic AMP; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Genistein; Hydroxyeicosatetraenoic Acids; Kidney Medulla; Lactams, Macrocyclic; Loop of Henle; Male; Nitric Oxide; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Signal Transduction; Sodium	1999
Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5 Topics: Acetylcholine; Amides; Angiotensin II; Animals; Arterioles; Blood Pressure; Cardiovascular Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Hypertension, Renal; Male; Microscopy, Video; Mixed Function Oxygenases; Muscle, Skeletal; Nitroprusside; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sulfones	2000
Angiotensin II modulates ion transport in rat proximal tubules through CYP metabolites. Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2 Topics: Adrenalectomy; Angiotensin II; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Indomethacin; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Ouabain; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes	2000
Angiotensin II releases 20-HETE from rat renal microvessels. American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:3 Topics: Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acids; Arterioles; Capillaries; Cytochrome P-450 Enzyme System; Estrenes; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Imidazoles; Kidney; Losartan; Male; NADP; Phosphodiesterase Inhibitors; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Type C Phospholipases	2000
20-Hydroxyeicosatetraenoic acid mediates angiotensin ii-induced phospholipase d activation in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: Angiotensin II; Animals; Arachidonic Acids; Cells, Cultured; Ceramides; Cyclohexanones; Enzyme Inhibitors; Glycerophospholipids; Hydroxyeicosatetraenoic Acids; Isoenzymes; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Organophosphonates; Phospholipase D; Propranolol; Rabbits	2001
Involvement of cytochrome P450 metabolites in the vascular action of angiotensin II on the afferent arterioles. Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Arterioles; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Male; Miconazole; Norepinephrine; Rabbits; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents	2001
Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II. American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 283, Issue:1 Topics: Amides; Angiotensin II; Animals; Arachidonic Acid; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfones; Triazoles; Vasoconstriction; Vasoconstrictor Agents	2002
Regulation of renal microvascular 20-hydroxyeicosatetraenoic acid (20-HETE) levels. Advances in experimental medicine and biology, 2003, Volume: 525 Topics: Angiotensin II; Animals; Cytochrome P-450 Enzyme System; Hydroxyeicosatetraenoic Acids; Kidney; Rats; Renal Circulation; Sodium Chloride, Dietary	2003
Cytochrome P450 arachidonic acid metabolites modulate renal tubular function. Advances in experimental medicine and biology, 2003, Volume: 525 Topics: Angiotensin II; Animals; Arachidonic Acid; Calcium; Cytochrome P-450 Enzyme System; Hydroxyeicosatetraenoic Acids; Kidney Tubules; Rats	2003
Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:4 Topics: Adamantane; Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Epoxide Hydrolases; Hydroxyeicosatetraenoic Acids; Hypertension; In Vitro Techniques; Lauric Acids; Male; Mice; Mice, Inbred Strains; Natriuresis; Renal Circulation; Solubility; Sulfones; Vasoconstrictor Agents; Vasodilation	2005
Fenofibrate prevents the development of angiotensin II-dependent hypertension in mice. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:4 Topics: Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Fenofibrate; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Vasoconstrictor Agents	2005
Contribution of arachidonic acid metabolites derived via cytochrome P4504A to angiotensin II-induced neointimal growth. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:6 Topics: Angiotensin II; Animals; Arachidonic Acid; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cells, Cultured; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Hydroxyeicosatetraenoic Acids; Leukocyte Common Antigens; Male; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Tunica Intima	2005
Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE. American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:4 Topics: Adaptation, Physiological; Amidines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Dinoprostone; Hydroxyeicosatetraenoic Acids; Imidazoles; Indomethacin; Losartan; Male; Microcirculation; Nephrectomy; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Vasoconstriction; Vasoconstrictor Agents	2006
High dietary salt reduces the contribution of 20-HETE to arteriolar oxygen responsiveness in skeletal muscle. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:3 Topics: Angiotensin II; Animals; Arterioles; Hydroxyeicosatetraenoic Acids; Indomethacin; Male; Models, Animal; Muscle, Skeletal; Muscle, Smooth, Vascular; Norepinephrine; Oxygen; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Vasoconstriction	2007
Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1 Topics: Acetophenones; Angiotensin II; Blotting, Western; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hydroxyeicosatetraenoic Acids; Hypoxia-Inducible Factor 1, alpha Subunit; Reactive Oxygen Species; Signal Transduction; Superoxides; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2007
Endothelial dysfunction and improvement of the angiotensin II-reactivity in hypercholesterolemic rabbits: role of cyclooxygenase metabolites. European journal of pharmacology, 2008, Feb-02, Volume: 580, Issue:1-2 Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cholesterol, Dietary; Cyclooxygenase 1; Dose-Response Relationship, Drug; Electrophysiology; Endothelium, Vascular; Hydroxyeicosatetraenoic Acids; Hypercholesterolemia; Male; Nitric Oxide; Rabbits; Vasoconstriction; Vasoconstrictor Agents	2008
Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes. Autonomic & autacoid pharmacology, 2009, Volume: 29, Issue:1-2 Topics: Amidines; Angiotensin II; Animals; Blood Glucose; Body Weight; Carbachol; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Histamine; Hydroxyeicosatetraenoic Acids; Kidney; Male; Mesenteric Arteries; Microsomes; Nitroprusside; Norepinephrine; Perfusion; Rats; Rats, Wistar; Renal Artery; Triazoles; Vasoconstriction; Vasodilation	2009
Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats. Clinical science (London, England : 1979), 2010, Feb-23, Volume: 118, Issue:10 Topics: 8,11,14-Eicosatrienoic Acid; Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Evaluation, Preclinical; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Multiple Organ Failure; Norepinephrine; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renal Circulation; Sulfones; Vasoconstrictor Agents	2010
CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent. Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:5 Topics: Amidines; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blotting, Western; Cells, Cultured; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Hydroxyeicosatetraenoic Acids; Hypertension; Lentivirus; Lisinopril; Losartan; Mass Spectrometry; Oligonucleotide Array Sequence Analysis; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Time Factors	2010
20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1. American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:4 Topics: Adult; Aged; Amidines; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Platelets; Calcium Channels; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelin-1; Humans; Hydroxyeicosatetraenoic Acids; Imidazoles; Ionophores; Irbesartan; Male; Middle Aged; Neutrophils; Oligopeptides; Peptides, Cyclic; Piperidines; Pyridines; Tetrazoles; Young Adult	2011
Induction of angiotensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction. Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:8 Topics: Acetylcholine; Angiotensin II; Cells, Cultured; Endothelial Cells; Enzyme Induction; Humans; Hydroxyeicosatetraenoic Acids; I-kappa B Kinase; Peptidyl-Dipeptidase A; Protein-Tyrosine Kinases; Renin-Angiotensin System; Superoxides	2012
Roles played by 20-HETE, angiotensin II and endothelin in mediating the hypertension in aging female spontaneously hypertensive rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Volume: 304, Issue:3 Topics: Aging; Angiotensin II; Animals; Blood Pressure; Endothelins; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Rats; Rats, Inbred SHR	2013
Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:11 Topics: Actins; Adaptation, Physiological; Aging; Angiotensin II; Animals; Behavior, Animal; Blood-Brain Barrier; Cerebrovascular Circulation; Cytokines; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microvessels; Middle Cerebral Artery; TRPC Cation Channels; TRPC6 Cation Channel; Up-Regulation	2013
Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice. American journal of physiology. Heart and circulatory physiology, 2013, Volume: 305, Issue:12 Topics: Aging; Angiotensin II; Animals; Calcium; Calcium Signaling; Hydroxyeicosatetraenoic Acids; Hypertension; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Mice; Mice, Inbred C57BL; Middle Cerebral Artery; Muscle Contraction; Muscle, Smooth, Vascular; TRPC Cation Channels; Vasoconstriction	2013
20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels. PloS one, 2013, Volume: 8, Issue:12 Topics: Angiotensin II; Animals; Calcium; Gene Expression; Hydroxyeicosatetraenoic Acids; Ionomycin; Male; Microvessels; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phospholipases A2; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Receptors, Angiotensin; Renal Circulation; Type C Phospholipases; Vasoconstrictor Agents	2013
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension. American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Jul-01, Volume: 309, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Mice, Transgenic; Microvessels; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Time Factors; Vascular Remodeling	2015
20-Hydroxyeicosatetraenoic Acid Is a Key Mediator of Angiotensin II-induced Apoptosis in Cardiac Myocytes. Journal of cardiovascular pharmacology, 2015, Volume: 66, Issue:1 Topics: Angiotensin II; Animals; Apoptosis; Cells, Cultured; Hydroxyeicosatetraenoic Acids; Myocytes, Cardiac; Rats; Rats, Wistar	2015
Angiotensin II upregulates CYP4A isoform expression in the rat kidney through angiotensin II type 1 receptor. Prostaglandins & other lipid mediators, 2018, Volume: 139 Topics: Angiotensin II; Animals; Arachidonic Acid; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cytochrome P-450 CYP4A; Disease Models, Animal; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Protein Isoforms; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles	2018
Thrombin Inhibition Prevents Endothelial Dysfunction and Reverses 20-HETE Overproduction without Affecting Blood Pressure in Angiotensin II-Induced Hypertension in Mice. International journal of molecular sciences, 2021, Aug-12, Volume: 22, Issue:16 Topics: Angiotensin II; Animals; Antithrombins; Chromatography, Liquid; Dabigatran; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Hypertension; Intercellular Adhesion Molecule-1; Male; Mice; Nitric Oxide; Tandem Mass Spectrometry; Vascular Remodeling; von Willebrand Factor	2021