20-hydroxy-5,8,11,14-eicosatetraenoic acid and 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide in 2 studies

Compound Research Comparison

Studies (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Trials (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Recent Studies (post-2010) (20-hydroxy-5,8,11,14-eicosatetraenoic acid)	Studies (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)	Trials (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)	Recent Studies (post-2010) (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
640	13	233	73	0	8

Protein Interaction Comparison

Protein	Taxonomy	20-hydroxy-5,8,11,14-eicosatetraenoic acid (IC50)	5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide (IC50)
Endothelin-1 receptor	Homo sapiens (human)		0.23
Endothelin-1 receptor	Rattus norvegicus (Norway rat)		0.015

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hercule, HC; Oyekan, AO	2

Other Studies

2 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide

Article	Year
Cytochrome P450 omega/omega-1 hydroxylase-derived eicosanoids contribute to endothelin(A) and endothelin(B) receptor-mediated vasoconstriction to endothelin-1 in the rat preglomerular arteriole. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3 Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arterioles; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dansyl Compounds; Endothelin-1; Hydroxyeicosatetraenoic Acids; Kidney; Male; Mixed Function Oxygenases; Oligopeptides; Piperidines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction	2000
Role of NO and cytochrome P-450-derived eicosanoids in ET-1-induced changes in intrarenal hemodynamics in rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6 Topics: Animals; Blood Pressure; Cytochrome P-450 Enzyme System; Dansyl Compounds; Eicosanoids; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Hemodynamics; Hydroxyeicosatetraenoic Acids; Indomethacin; Kidney Cortex; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Regional Blood Flow; Renal Artery; Renal Circulation; Vascular Resistance	2000

Article

Year

Cytochrome P450 omega/omega-1 hydroxylase-derived eicosanoids contribute to endothelin(A) and endothelin(B) receptor-mediated vasoconstriction to endothelin-1 in the rat preglomerular arteriole.

The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3

Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arterioles; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dansyl Compounds; Endothelin-1; Hydroxyeicosatetraenoic Acids; Kidney; Male; Mixed Function Oxygenases; Oligopeptides; Piperidines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction

2000

Role of NO and cytochrome P-450-derived eicosanoids in ET-1-induced changes in intrarenal hemodynamics in rats.

American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6

Topics: Animals; Blood Pressure; Cytochrome P-450 Enzyme System; Dansyl Compounds; Eicosanoids; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Hemodynamics; Hydroxyeicosatetraenoic Acids; Indomethacin; Kidney Cortex; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Regional Blood Flow; Renal Artery; Renal Circulation; Vascular Resistance

2000