20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with 11,12-epoxy-5,8,14-eicosatrienoic acid in 15 studies
| Studies (20-hydroxy-5,8,11,14-eicosatetraenoic acid) | Trials (20-hydroxy-5,8,11,14-eicosatetraenoic acid) | Recent Studies (post-2010) (20-hydroxy-5,8,11,14-eicosatetraenoic acid) | Studies (11,12-epoxy-5,8,14-eicosatrienoic acid) | Trials (11,12-epoxy-5,8,14-eicosatrienoic acid) | Recent Studies (post-2010) (11,12-epoxy-5,8,14-eicosatrienoic acid) |
|---|---|---|---|---|---|
| 640 | 13 | 233 | 255 | 3 | 75 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carroll, MA; Falck, JR; Garcia, MP; McGiff, JC | 1 |
| Ma, YH; Roman, RJ; Schwartzman, ML | 1 |
| Imig, JD; Ortiz de Montellano, PR; Roman, RJ; Sui, Z; Zou, AP | 1 |
| Balazy, M; Mastyugin, V; Roman, RJ; Schwartzman, ML; Stec, DE; Wang, MH; Yang, CS | 1 |
| Funae, Y; Imaoka, S | 1 |
| Falck, JR; Nguyen, X; Reddy, KM; Schwartzman, ML; Wang, MH | 1 |
| Campbell, WB; Ge, ZD; Li, PL; Zhang, DX | 1 |
| Norris, AW; Spector, AA; Van Der Veer, J; Widstrom, RL | 1 |
| Laniado-Schwartzman, M; Miyata, N; Seki, T; Wang, MH | 1 |
| Hollenberg, PF; Kent, UM; Kornilov, AM; Snider, NT | 1 |
| Falck, JR; Huang, Y; Kroetz, DL; Lin, ET; Ng, VY; Reddy, LM | 1 |
| Fava, C; Jiang, H; Lechi, A; McGiff, JC; Minuz, P; Morganti, A; Patrignani, P; Ricci, M; Tacconelli, S; Turolo, L | 1 |
| Certíková Chábová, V; Cervenka, L; Falck, JR; Hammock, BD; Imig, JD; Kompanowska-Jezierska, E; Kopkan, L; Kramer, HJ; Kujal, P; Sadowski, J; Vanecková, I; Vanourková, Z; Vernerová, Z; Walkowska, A | 1 |
| Bolognesi, M; Gaiani, S; Gatta, A; Jiang, H; McGiff, JC; Sacerdoti, D | 1 |
| Althurwi, HN; El-Kadi, AO; Elshenawy, OH | 1 |
1 review(s) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and 11,12-epoxy-5,8,14-eicosatrienoic acid
| Article | Year |
|---|---|
[The physiological role of P450-derived arachidonic acid metabolites].
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Blood Pressure; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Hydroxyeicosatetraenoic Acids; Ion Transport; Mixed Function Oxygenases; Rats; Rats, Inbred SHR; Vasoconstriction | 1998 |
14 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and 11,12-epoxy-5,8,14-eicosatrienoic acid
| Article | Year |
|---|---|
Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Eicosanoids; Free Radicals; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney; Male; Prostaglandin-Endoperoxide Synthases; Rabbits; Renal Circulation; Vascular Resistance | 1992 |
Altered renal P-450 metabolism of arachidonic acid in Dahl salt-sensitive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Drug Resistance; Female; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Prostaglandins; Rats; Rats, Inbred Strains; Sodium Chloride | 1994 |
Cytochrome P-450 inhibitors alter afferent arteriolar responses to elevations in pressure.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arterioles; Cytochrome P-450 Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney; Kidney Cortex; Miconazole; Microsomes; Muscle, Smooth, Vascular; Oxazines; Perfusion; Rats; Rats, Sprague-Dawley; Renal Circulation | 1994 |
Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Baculoviridae; Capillaries; Catalysis; Cell Line; Cloning, Molecular; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; DNA, Complementary; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Hydroxylation; Kidney; Lauric Acids; Microsomes; Mixed Function Oxygenases; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Spodoptera | 1996 |
Kinetic profile of the rat CYP4A isoforms: arachidonic acid metabolism and isoform-specific inhibitors.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Catalysis; Cell Line; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids; Female; Hydroxyeicosatetraenoic Acids; Hydroxylation; Insecta; Kinetics; Male; Mixed Function Oxygenases; Oxidation-Reduction; Protein Isoforms; Rats; Recombinant Proteins | 1999 |
Role of ADP-ribose in 11,12-EET-induced activation of K(Ca) channels in coronary arterial smooth muscle cells.
Topics: 8,11,14-Eicosatrienoic Acid; Adenosine Diphosphate Ribose; Animals; Arachidonic Acid; Arterioles; Cattle; Coronary Vessels; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Nitroprusside; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Vasodilation | 2002 |
Fatty acid-binding proteins inhibit hydration of epoxyeicosatrienoic acids by soluble epoxide hydrolase.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acids; Binding, Competitive; Carrier Proteins; Epoxide Hydrolases; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Hydroxyeicosatetraenoic Acids; Kinetics; Ligands; Linoleic Acid; Models, Chemical; Myocardium; Neoplasm Proteins; Nerve Tissue Proteins; Oleic Acid; Rats; Recombinant Proteins; Solubility; Water | 2003 |
Cytochrome P450 4A isoform inhibitory profile of N-hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine (HET0016), a selective inhibitor of 20-HETE synthesis.
Topics: 8,11,14-Eicosatrienoic Acid; Amidines; Animals; Arachidonic Acid; Cell Membrane; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Kinetics; Oxidation-Reduction; Rats | 2005 |
Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides.
Topics: 8,11,14-Eicosatrienoic Acid; Arachidonic Acids; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Endocannabinoids; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Kidney; Kinetics; Microsomes, Liver; Polyunsaturated Alkamides; Spectrometry, Mass, Electrospray Ionization | 2007 |
Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Apolipoprotein A-I; Apolipoprotein A-II; Aryl Hydrocarbon Hydroxylases; Cell Line, Tumor; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Cytochrome P450 Family 4; Dose-Response Relationship, Drug; Eicosanoids; Epoxide Hydrolases; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Hydroxyeicosatetraenoic Acids; Peroxisome Proliferators; PPAR alpha; PPAR gamma; Pyrimidines; Rats; Rats, Sprague-Dawley; Response Elements; Retinoid X Receptors; RNA, Messenger; Steroid 16-alpha-Hydroxylase; Transcriptional Activation; Transfection | 2007 |
Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease.
Topics: 8,11,14-Eicosatrienoic Acid; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Arachidonic Acids; Case-Control Studies; Creatinine; Cross-Sectional Studies; Cytochrome P-450 Enzyme System; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Hypertension, Renovascular; Male; Middle Aged; Renal Artery Obstruction | 2008 |
Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.
Topics: 8,11,14-Eicosatrienoic Acid; Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Evaluation, Preclinical; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Multiple Organ Failure; Norepinephrine; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renal Circulation; Sulfones; Vasoconstrictor Agents | 2010 |
11,12-EET increases porto-sinusoidal resistance and may play a role in endothelial dysfunction of portal hypertension.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Endothelin-1; Hepatic Veins; Hydroxyeicosatetraenoic Acids; Hypertension, Portal; Infusion Pumps; Liver; Liver Cirrhosis, Experimental; Male; Miconazole; Organ Culture Techniques; Oxidoreductases; Phenylephrine; Portal Pressure; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction; Vasodilation | 2011 |
Fenofibrate modulates cytochrome P450 and arachidonic acid metabolism in the heart and protects against isoproterenol-induced cardiac hypertrophy.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cardiomegaly; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Fenofibrate; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Hypolipidemic Agents; Isoproterenol; Male; Rats; Rats, Sprague-Dawley | 2014 |