Page last updated: 2024-09-03

20-hydroxy-5,8,11,14-eicosatetraenoic acid and 1-aminobenzotriazole

20-hydroxy-5,8,11,14-eicosatetraenoic acid has been researched along with 1-aminobenzotriazole in 17 studies

Compound Research Comparison

Studies
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Trials
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Recent Studies (post-2010)
(20-hydroxy-5,8,11,14-eicosatetraenoic acid)
Studies
(1-aminobenzotriazole)
Trials
(1-aminobenzotriazole)
Recent Studies (post-2010) (1-aminobenzotriazole)
64013233222077

Protein Interaction Comparison

ProteinTaxonomy20-hydroxy-5,8,11,14-eicosatetraenoic acid (IC50)1-aminobenzotriazole (IC50)
Cytochrome P450 3A4Homo sapiens (human)0.45

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's11 (64.71)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaushal, KM; Kroetz, DL; Su, P1
Alonso-Galicia, M; Falck, JR; Henderson, L; Maier, KG; Narayanan, J; Roman, RJ1
Laniado-Schwartzman, M; Nasjletti, A; Wang, MH; Zand, BA1
Alonso-Galicia, M; Cowley, AW; Greene, AS; Maier, KG; Roman, RJ1
Flasch, AK; Hoagland, KM; Roman, RJ1
Dahly-Vernon, AJ; Dos Santos, EA; Hoagland, KM; Roman, RJ1
Akhtar, S; Benter, IF; Canatan, H; Yousif, MH1
Cowley, AW; Ito, O; Ito, S; Kohzuki, M; Mori, T; Roman, RJ; Sarkis, A; Verbalis, J1
Blanton, A; Hercule, H; Nsaif, R; Oyekan, A1
Flasch, AK; Lopez, B; Roman, RJ; Ryan, RP; Sarkis, A; Williams, JM1
Badzyńska, B; Kompanowska-Jezierska, E; Kuczeriszka, M1
Akhtar, S; Benter, IF; Dahly-Vernon, AJ; Dunn, KM; Roman, RJ; Yousif, MH1
Blair, IA; Christmas, P; Cooper, PR; Douaidy, K; Mesaros, AC; Mittelman, MA; Panettieri, RA; Soberman, RJ; Stark, CM; Zhang, J1
Baker, R; Davis, DD; Fan, F; Lima, R; Moulana, M; Reckelhoff, JF; Roman, RJ; Romero, DG; Ryan, MJ; Yanes, LL; Yuan, K; Zhang, H1
Fernandez, MM; Gonzalez, D; Nowicki, S; Roman, RJ; Williams, JM1
Baker, RC; Chen, BB; Fan, F; Johnson, DA; Liu, H; Orozco, LD; Perkins, E; Roman, RJ1
Červenka, L; Dobrowolski, L; Hammock, BD; Kompanowska-Jezierska, E; Kuczeriszka, M; Olszyñski, KH; Sadowski, J; Walkowska, A1

Other Studies

17 other study(ies) available for 20-hydroxy-5,8,11,14-eicosatetraenoic acid and 1-aminobenzotriazole

ArticleYear
Inhibition of renal arachidonic acid omega-hydroxylase activity with ABT reduces blood pressure in the SHR.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Animals; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Kinetics; Male; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Reference Values; Triazoles

1998
Fluorescent HPLC assay for 20-HETE and other P-450 metabolites of arachidonic acid.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:2

    Topics: Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Indicators and Reagents; Kidney Cortex; Microsomes; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Triazoles

2000
Renal 20-hydroxyeicosatetraenoic acid synthesis during pregnancy.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:2

    Topics: Animals; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Hydroxyeicosatetraenoic Acids; Isoenzymes; Kidney; Loop of Henle; Microcirculation; Mixed Function Oxygenases; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Sodium; Triazoles

2002
Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 283, Issue:1

    Topics: Amides; Angiotensin II; Animals; Arachidonic Acid; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfones; Triazoles; Vasoconstriction; Vasoconstrictor Agents

2002
Inhibitors of 20-HETE formation promote salt-sensitive hypertension in rats.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:4

    Topics: Amidines; Animals; Arachidonic Acid; Blood Pressure; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Triazoles

2003
Inhibition of the formation of EETs and 20-HETE with 1-aminobenzotriazole attenuates pressure natriuresis.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 287, Issue:1

    Topics: Animals; Arachidonic Acid; Blood Pressure; Blotting, Western; Centrifugation, Density Gradient; Cytochrome P-450 Enzyme Inhibitors; Eicosanoids; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Immunohistochemistry; Kidney; Kidney Cortex; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Triazoles

2004
Inhibition of Ca2+/calmodulin-dependent protein kinase II, RAS-GTPase and 20-hydroxyeicosatetraenoic acid attenuates the development of diabetes-induced vascular dysfunction in the rat carotid artery.
    Pharmacological research, 2005, Volume: 52, Issue:3

    Topics: Amidines; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carotid Arteries; Carotid Artery Diseases; Diabetes Mellitus, Experimental; Hydroxyeicosatetraenoic Acids; Monomeric GTP-Binding Proteins; Organophosphonates; Protein Kinase Inhibitors; Rats; Rats, Wistar; Streptozocin; Sulfonamides; Triazoles; Vascular Diseases; Vasoconstriction; Vasodilation

2005
Cytochrome P-450-dependent metabolism of arachidonic acid in the kidney of rats with diabetes insipidus.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cytochrome P-450 CYP4A; Dehydration; Diabetes Insipidus; Hydroxyeicosatetraenoic Acids; Kidney; Male; Oxytocin; Rats; Rats, Inbred BB; Rats, Long-Evans; Triazoles

2005
Nitric oxide/cytochrome P450 interactions in cyclosporin A-induced effects in the rat.
    Journal of hypertension, 2006, Volume: 24, Issue:9

    Topics: Amidines; Animals; Arginine; Blood Pressure; Bradykinin; Cyclosporine; Cytochrome P-450 Enzyme System; Endothelin-1; Hydroxyeicosatetraenoic Acids; Kidney; Male; Microsomes; Nitric Oxide; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Triazoles

2006
Elevations in renal interstitial hydrostatic pressure and 20-hydroxyeicosatetraenoic acid contribute to pressure natriuresis.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:3

    Topics: Amidines; Animals; Arachidonic Acids; Blood Pressure; Enzyme Inhibitors; Hydrostatic Pressure; Hydroxyeicosatetraenoic Acids; Kidney Cortex; Male; Natriuresis; Rats; Triazoles

2007
Cytochrome P-450 monooxygenases in control of renal haemodynamics and arterial pressure in anaesthetized rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 11

    Topics: Amidines; Animals; Arachidonic Acid; Blood Pressure; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hemodynamics; Hydroxyeicosatetraenoic Acids; Kidney; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Male; Nitric Oxide; Rats; Rats, Wistar; Renal Circulation; Triazoles; Vasoconstrictor Agents; Vasodilation

2006
Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes.
    Autonomic & autacoid pharmacology, 2009, Volume: 29, Issue:1-2

    Topics: Amidines; Angiotensin II; Animals; Blood Glucose; Body Weight; Carbachol; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Histamine; Hydroxyeicosatetraenoic Acids; Kidney; Male; Mesenteric Arteries; Microsomes; Nitroprusside; Norepinephrine; Perfusion; Rats; Rats, Wistar; Renal Artery; Triazoles; Vasoconstriction; Vasodilation

2009
20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice.
    PloS one, 2010, Apr-20, Volume: 5, Issue:4

    Topics: Animals; Bronchial Hyperreactivity; Carbachol; Hydroxyeicosatetraenoic Acids; Lipid Peroxidation; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Neutrophils; Ozone; Respiratory Hypersensitivity; Triazoles

2010
Postmenopausal hypertension: role of 20-HETE.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:6

    Topics: Aging; Animals; Blood Pressure; Cytochrome P-450 CYP4A; Disease Models, Animal; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Postmenopause; Rats; Rats, Inbred SHR; Triazoles

2011
Inhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine.
    European journal of pharmacology, 2012, Jul-05, Volume: 686, Issue:1-3

    Topics: Amidines; Animals; Cytochrome P-450 CYP4A; Dopamine; Glomerular Filtration Rate; Hydroxyeicosatetraenoic Acids; Kidney Cortex; Liver; Male; Natriuretic Agents; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Triazoles

2012
20-Hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 346, Issue:1

    Topics: Amidines; Angioplasty, Balloon, Coronary; Animals; Carotid Artery Injuries; Carotid Artery, Common; Carotid Stenosis; Cell Movement; Cell Proliferation; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Disease Models, Animal; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hyperplasia; Male; Muscle, Smooth, Vascular; Neointima; Rats; Rats, Sprague-Dawley; Triazoles; Tunica Intima

2013
High salt intake increases blood pressure in normal rats: putative role of 20-HETE and no evidence on changes in renal vascular reactivity.
    Kidney & blood pressure research, 2015, Volume: 40, Issue:3

    Topics: Acetylcholine; Animals; Arterial Pressure; Blood Pressure; Epoxide Hydrolases; Hydroxyeicosatetraenoic Acids; Male; Nitric Oxide; Norepinephrine; Osmolar Concentration; Rats; Rats, Wistar; Renal Circulation; Sodium, Dietary; Triazoles

2015