Compounds > 2-pyrrolino-dox
Page last updated: 2024-09-03

2-pyrrolino-dox and verapamil

2-pyrrolino-dox has been researched along with verapamil in 1 studies

Compound Research Comparison

Studies
(2-pyrrolino-dox)		Trials
(2-pyrrolino-dox)		Recent Studies (post-2010)
(2-pyrrolino-dox)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
280217,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomy2-pyrrolino-dox (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blanc, E; Castex, C; Clair, P; Merida, P; Rees, AR; Temsamani, J1

Other Studies

1 other study(ies) available for 2-pyrrolino-dox and verapamil

ArticleYear
2-Pyrrolinodoxorubicin and its peptide-vectorized form bypass multidrug resistance.
    Anti-cancer drugs, 2004, Volume: 15, Issue:6

    Topics: Adjuvants, Pharmaceutic; Biological Transport; Carrier Proteins; Cell Division; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Gene Expression; Genes, MDR; Humans; Intracellular Fluid; K562 Cells; Pyrroles; Tumor Cells, Cultured; Verapamil

2004