2-piperidone has been researched along with thalidomide in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Koch, H; Pischek, G | 1 |
| Kyogoku, Y; Yu, NT | 1 |
| Koch, H; Köhler, F | 1 |
| Shull, GE | 1 |
| SOMERS, GF | 1 |
| PARKASH, O | 1 |
| BERITIC, T; MARKICEVIC, A | 1 |
| FRATTA, I; SIGG, EB; WUEST, HM | 1 |
| Duveau, DY; Figg, WD; Lepper, ER; Luzzio, FA | 1 |
| Meng, Y; Tian, C; Wang, Z; Xiu, P; Zhao, W; Zhou, R | 1 |
| Czarnik, AW; DeWitt, SH; Jacques, V; Judge, TM; Van der Ploeg, LH | 1 |
| Amantangelo, MD; Barnes, L; Bjorklund, C; Breider, M; Cai, T; Chiu, H; Chopra, R; Couto, S; Daniel, TO; Fontanillo, C; Gandhi, AK; Hagner, PR; Havens, CG; Kang, J; Khambatta, G; Klippel, A; Kosek, J; Lopez-Girona, A; Lu, G; Man, HW; Narla, RK; Pourdehnad, M; Raymon, H; Rychak, E; Schafer, PH; Thakurta, A; Trotter, M; Waldman, M; Wang, M | 1 |
| Haq, W; Tiwari, VS; Yadav, SR | 1 |
| Amatangelo, M; Bjorklund, CC; Chiu, H; Couto, S; Flynt, JE; Kang, J; Katz, M; Ortiz, M; Pierceall, W; Polonskaia, A; Ren, Y; Thakurta, A; Towfic, F; Wang, M | 1 |
1 trial(s) available for 2-piperidone and thalidomide
| Article | Year |
|---|---|
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; B-Lymphocytes; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Ikaros Transcription Factor; Interferon Regulatory Factor-7; Interferons; Lenalidomide; Lentivirus; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, SCID; Molecular Mimicry; Peptide Hydrolases; Piperidones; Proteolysis; Quinazolinones; RNA, Small Interfering; Signal Transduction; T-Lymphocytes; Thalidomide; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2015 |
13 other study(ies) available for 2-piperidone and thalidomide
| Article | Year |
|---|---|
[The biologic half-life of the thalidomide-like compound K-2004 (author's transl)].
Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Half-Life; Hypnotics and Sedatives; Intestinal Absorption; Male; Piperidines; Piperidones; Rats; Thalidomide | 1975 |
Specific H-bonding of glutarimides and hydantoins to derivatives of RNA bases in chloroform solution.
Topics: Bemegride; Chemical Phenomena; Chemistry; Chloroform; Cycloheximide; Ethosuximide; Glutethimide; Hydantoins; Pemoline; Phenobarbital; Phenytoin; Piperidines; Piperidones; Primidone; RNA; Spectrophotometry, Infrared; Thalidomide | 1973 |
[Teratological study on the thalidomide-like compounds K-2004 and K-2604 in the mouse and rat].
Topics: Abnormalities, Drug-Induced; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Drug Evaluation, Preclinical; Female; Fetus; Hypnotics and Sedatives; Imides; Injections, Intraperitoneal; Mice; Piperidines; Piperidones; Pregnancy; Rats; Teratogens; Thalidomide | 1974 |
Differential inhibition of protein synthesis: a possible biochemical mechanism of thalidomide teratogenesis.
Topics: Abnormalities, Drug-Induced; Acylation; Animals; Chemical Phenomena; Chemistry; Cycloheximide; Embryonic and Fetal Development; Gene Expression Regulation; Humans; Imides; Models, Biological; Piperidones; Polyamines; Protein Biosynthesis; Pyrimidines; Rabbits; RNA, Messenger; Teratogens; Thalidomide | 1984 |
Pharmacological properties of thalidomide (alpha-phthalimido glutarimide), a new sedative hypnotic drug.
Topics: Animals; Barbiturates; Central Nervous System Depressants; Glutamates; Hypnotics and Sedatives; Mice; Piperidones; Sleep; Thalidomide; Tranquilizing Agents | 1960 |
[Abnormalities caused by Contergan (thalidomide, N-phtalimido-glutarimide) in Drosophila melanogaster].
Topics: Animals; Congenital Abnormalities; Drosophila; Drosophila melanogaster; Piperidones; Thalidomide | 1962 |
[Teratogenic effects of glutarimide derivatives].
Topics: Ectromelia; Piperidones; Thalidomide | 1962 |
PHARMACOLOGICAL PROPERTIES AND TERATOGENIC ACTION OF 2-(HEXAHYDROPHTHALIMIDO) GLUTARIMIDE AND 2-PHTHALIMIDO-N-METHYLGLUTARIMIDE.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Mice; Piperidines; Piperidones; Pregnancy; Pregnancy, Animal; Rabbits; Research; Thalidomide; Toxicology | 1964 |
Synthesis of racemic cis-5-hydroxy-3-phthalimidoglutarimide. A metabolite of thalidomide isolated from human plasma.
Topics: Humans; Molecular Structure; Phthalimides; Piperidones; Stereoisomerism; Thalidomide | 2005 |
Enantiomerization mechanism of thalidomide and the role of water and hydroxide ions.
Topics: Catalysis; Hydroxides; Molecular Conformation; Piperidones; Quantum Theory; Stereoisomerism; Thalidomide; Thermodynamics; Water | 2012 |
Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Female; Humans; Inflammation; Leukocytes, Mononuclear; Mice; Mice, SCID; Models, Chemical; Neoplasm Transplantation; Neoplasms; Piperidones; Quinazolinones; Stereoisomerism; Thalidomide; Tumor Necrosis Factor-alpha | 2015 |
Stereoselective Synthesis of (R)-3-Methylthalidomide by Piperidin-2-one Ring Assembly Approach.
Topics: Chemistry Techniques, Synthetic; Hydrogen-Ion Concentration; Piperidines; Piperidones; Stereoisomerism; Thalidomide | 2015 |
Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with dysregulated CRBN.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Resistance, Neoplasm; Heterocyclic Compounds, 4 or More Rings; Humans; Lenalidomide; Leukocytes, Mononuclear; Morpholines; Multiple Myeloma; Phthalimides; Piperidones; Thalidomide; Tumor Cells, Cultured; Ubiquitin-Protein Ligases | 2020 |