Page last updated: 2024-08-21

2-piperidone and sulphostin

2-piperidone has been researched along with sulphostin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Abe, M; Akiyama, T; Aoyagi, T; Hamada, M; Harada, S; Homma, Y; Kojima, F; Muraoka, Y; Naganawa, H; Sawa, R; Takahashi, Y; Takeuchi, T; Yamaguchi, A1
Abe, M; Akiyama, T; Harada, S; Kojima, F; Muraoka, Y; Nakamura, H1
Abe, M; Akiyama, T; Ichikawa, Y; Muraoka, Y; Nagai, M; Umezawa, Y; Yamamoto, K; Yamazaki, H1
Abe, F; Abe, M; Ichimura, E; Ichinei, M; Muraoka, Y; Nishimura, C; Ogasawara, A; Saino, T1
Hu, Y; Liu, T; Liu, Y1
Bechtold, M; Femmer, C; Held, M; Panke, S1

Reviews

1 review(s) available for 2-piperidone and sulphostin

ArticleYear
Recent advances in non-peptidomimetic dipeptidyl peptidase 4 inhibitors: medicinal chemistry and preclinical aspects.
    Current medicinal chemistry, 2012, Volume: 19, Issue:23

    Topics: Amines; Chemistry, Pharmaceutical; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Evaluation, Preclinical; Humans; Hypoglycemic Agents; Organophosphorus Compounds; Peptidomimetics; Piperidones; Quinolizines; Xanthines

2012

Other Studies

5 other study(ies) available for 2-piperidone and sulphostin

ArticleYear
Sulphostin, a potent inhibitor for dipeptidyl peptidase IV from Streptomyces sp. MK251-43F3.
    The Journal of antibiotics, 2001, Volume: 54, Issue:9

    Topics: Dipeptidyl Peptidase 4; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphorus Compounds; Piperidones; Protease Inhibitors; Streptomyces

2001
First synthesis and determination of the absolute configuration of sulphostin, a novel inhibitor of dipeptidyl peptidase IV.
    Journal of natural products, 2004, Volume: 67, Issue:6

    Topics: Animals; Catalysis; Crystallography, X-Ray; Dipeptidyl Peptidase 4; Inhibitory Concentration 50; Molecular Conformation; Molecular Structure; Organophosphorus Compounds; Piperidones; Protease Inhibitors; Rats; Stereoisomerism; Streptomyces; Structure-Activity Relationship

2004
Synthesis and biological activity of sulphostin analogues, novel dipeptidyl peptidase IV inhibitors.
    Bioorganic & medicinal chemistry, 2005, Feb-01, Volume: 13, Issue:3

    Topics: Animals; Dipeptidyl Peptidase 4; Drug Design; Enzyme Inhibitors; Kidney; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Piperidones; Rats

2005
Sulphostin, a novel inhibitor of dipeptidyl peptidases IV (DPPIV) that stimulates hematopoiesis in mice.
    The Journal of antibiotics, 2005, Volume: 58, Issue:2

    Topics: Alkylating Agents; Animals; Bone Marrow Cells; Cyclophosphamide; Cytokines; Dipeptidyl Peptidase 4; Enzyme-Linked Immunosorbent Assay; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Leukocyte Count; Leukopenia; Male; Mice; Mice, Inbred ICR; Neutrophils; Organophosphorus Compounds; Piperidones; Protease Inhibitors; Stimulation, Chemical

2005
In vivo directed enzyme evolution in nanoliter reactors with antimetabolite selection.
    Metabolic engineering, 2020, Volume: 59

    Topics: Amino Acid Isomerases; Antimetabolites; Directed Molecular Evolution; Organophosphorus Compounds; Piperidones; Protein Engineering

2020