Page last updated: 2024-08-21

2-piperidone and nsc 4347

2-piperidone has been researched along with nsc 4347 in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (28.57)29.6817
2010's13 (61.90)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Alves, AP; Bezerra, DP; Castro, FO; Costa-Lotufo, LV; Elmiro, FJ; Lima, MA; Moraes, MO; Pessoa, C; Silveira, ER1
Bezerra, DP; Costa-Lotufo, LV; de Castro, FO; de Moraes, MO; Elmiro, FJ; Lima, MA; Militão, GC; Pessoa, C; Silveira, ER1
Alexandre Silveira, J; Cícero Bezerra Felipe, F; de Barros Viana, GS; de Oliveira Souza, LE; Deusdênia Loiola Pessoa, O; Esdras de Andrade Uchoa, D; Rocha Silveira, E; Trajano Sousa Filho, J1
Kato, MJ; Lago, JH1
Bezerra, DP; Costa-Lotufo, LV; de Moraes, MO; de Vasconcellos, MC; e Silva, AC; Henriques, JA; Lima, MA; Moura, DJ; Rosa, RM; Saffi, J; Silveira, ER1
Jyothi, D; Madhusudana Rao, J; Mangala Gowri, P; Rama Subba Rao, V; Sreedhar, AS; Vanathi, P1
Kato, MJ; Kawano, T; Lopes, PO; Moraes, Jd; Nakano, E; Nascimento, C; Yamaguchi, LF1
Frébault, F; Maulide, N1
de Moraes, J; Kato, MJ; Nakano, E; Nascimento, C; Yamaguchi, LF1
Akileshwari, C; Babu, KH; Babu, KS; Chandra Kumar, RS; Muthenna, P; Petrash, JM; Prasad, KR; Rao, JM; Rao, VR; Reddy, GB; Shankaraiah, G; Suresh, G; Yadav, PA1
Huang, CG; Huang, XZ; Jiang, ZY; Liu, WF1
Bezerra, DP; Costa-Lotufo, LV; de Moraes, MO; Pessoa, C; Saker-Neto, N; Silveira, ER1
Baggio, CH; Burci, LM; da Silva, LM; Facundo, VA; Marques, MC; Militão, JS; Pereira, IT; Rodrigues, RV; Santos, AR; Werner, MF1
Babu, KS; Kumar, JU; Kumar, RS; Pitke, VV; Poornima, B; Rao, GT; Shankaraiah, G; Sreedhar, AS1
Borrely, SI; Fokoue, HH; Kato, MJ; Lopes, PO; Marques, JV; Nakano, E; Ohlweiler, FP; Pereira, CA; Pinheiro, Ade S; Rapado, LN; Scotti, MT; Yamaguchi, LF1
Ferreira, B; Guimarães, A; Kato, M; Maleck, M; Mallet, J1
Bezerra, DP; Chammas, R; de Aquino, NC; Ferreira, PM; Machado, CM; Pessoa, C; Silveira, ER1
Devadasu, E; Subramanyam, R; Yadav, SA; Yeggoni, DP1
Gunia-Krzyżak, A; Koczurkiewicz, P; Pękala, E; Piska, K; Wójcik-Pszczoła, K1
Antar, GM; Cogo, RM; Lago, JHG; Mazloum, SF; Mendonça, PS; Mengarda, AC; Moraes, J; Morais, CS; Morais, TR; Salvadori, MC; Teixeira, FS1
Barbosa-Filho, JM; Bezerra, DP; Contessoto, NSA; Cornélio, ML; da Silveira, NJF; Girol, AP; Henrique, T; Oliani, SM; Silveira, ER; Stefanini, ACB; Tajara, EH; Zanon, CF1

Reviews

2 review(s) available for 2-piperidone and nsc 4347

ArticleYear
Overview of the therapeutic potential of piplartine (piperlongumine).
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Feb-14, Volume: 48, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Drugs, Investigational; Fruit; Humans; Medicine, Ayurvedic; Neoplasms; Patents as Topic; Piper; Piperidones

2013
Piperlongumine (piplartine) as a lead compound for anticancer agents - Synthesis and properties of analogues: A mini-review.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Animals; Antineoplastic Agents, Phytogenic; Chemistry Techniques, Synthetic; Dioxolanes; Drug Discovery; Humans; Neoplasms; Piper; Piperidones; Structure-Activity Relationship

2018

Other Studies

19 other study(ies) available for 2-piperidone and nsc 4347

ArticleYear
In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2006, Volume: 39, Issue:6

    Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Benzodioxoles; Cell Proliferation; Disease Models, Animal; Female; Kidney; Liver; Mice; Neoplasm Transplantation; Piper; Piperidines; Piperidones; Plant Extracts; Plant Roots; Polyunsaturated Alkamides; Sarcoma 180; Spleen

2006
Piplartine induces inhibition of leukemia cell proliferation triggering both apoptosis and necrosis pathways.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Activation; HL-60 Cells; Humans; In Vitro Techniques; K562 Cells; Leukemia; Leukemia, T-Cell; Microscopy, Fluorescence; Monocytes; Necrosis; Nucleic Acid Conformation; Piper; Piperidones; Signal Transduction

2007
Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2007, Volume: 14, Issue:9

    Topics: Alkaloids; Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Maze Learning; Mice; Pentylenetetrazole; Phytotherapy; Piper; Piperidones; Plant Extracts; Plant Roots; Seizures

2007
3alpha,4alpha-Epoxy-2-piperidone, a new minor derivative from leaves of Piper crassinervium Kunth (Piperaceae).
    Natural product research, 2007, Volume: 21, Issue:10

    Topics: Antifungal Agents; Cladosporium; Humans; Microbial Sensitivity Tests; Phytotherapy; Piper; Piperidones; Plant Extracts; Plant Leaves

2007
Evaluation of the genotoxicity of piplartine, an alkamide of Piper tuberculatum, in yeast and mammalian V79 cells.
    Mutation research, 2008, Apr-30, Volume: 652, Issue:2

    Topics: Animals; Apoptosis; Cell Cycle; Cell Line; Comet Assay; Cricetinae; Cricetulus; DNA Damage; Dose-Response Relationship, Drug; Membrane Potential, Mitochondrial; Mutagenicity Tests; Piper; Piperidones; Saccharomyces cerevisiae

2008
Diferuloylmethane augments the cytotoxic effects of piplartine isolated from Piper chaba.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression; HSP70 Heat-Shock Proteins; Humans; Mice; Piper; Piperidones; Plant Roots; Rats; Stereoisomerism

2009
Schistosoma mansoni: In vitro schistosomicidal activity of piplartine.
    Experimental parasitology, 2011, Volume: 127, Issue:2

    Topics: Animals; Biomphalaria; Cell Survival; Chlorocebus aethiops; Cricetinae; Female; Male; Mesocricetus; Microscopy, Confocal; Piper; Piperidones; Plant Extracts; Schistosoma mansoni; Vero Cells

2011
Total synthesis and structural revision of the piperarborenines: when photochemistry meets C-H activation.
    Angewandte Chemie (International ed. in English), 2012, Mar-19, Volume: 51, Issue:12

    Topics: Carbon; Dimerization; Hydrogen; Photochemical Processes; Piper; Piperidones

2012
Schistosoma mansoni: in vitro schistosomicidal activity and tegumental alterations induced by piplartine on schistosomula.
    Experimental parasitology, 2012, Volume: 132, Issue:2

    Topics: Animals; Biomphalaria; Cricetinae; Larva; Mesocricetus; Microscopy, Confocal; Piper; Piperidones; Plant Extracts; Praziquantel; Schistosoma mansoni; Schistosomicides; Time Factors

2012
Synthesis and biological evaluation of new piplartine analogues as potent aldose reductase inhibitors (ARIs).
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Aldehyde Reductase; Biological Transport; Drug Design; Enzyme Assays; Enzyme Inhibitors; Erythrocytes; Humans; Hypoglycemic Agents; Indoles; Molecular Docking Simulation; Piper; Piperidones; Plant Extracts; Plant Roots; Recombinant Proteins; Sorbitol; Structure-Activity Relationship

2012
New amide alkaloids from Piper longum.
    Fitoterapia, 2013, Volume: 84

    Topics: Alkaloids; Amides; Antiviral Agents; Biological Assay; Cell Line; Fruit; Hepatitis B virus; Hepatocytes; Humans; Molecular Structure; Piper; Piperidones

2013
Antiulcer and gastric antisecretory effects of dichloromethane fraction and piplartine obtained from fruits of Piper tuberculatum Jacq. in rats.
    Journal of ethnopharmacology, 2013, Jun-21, Volume: 148, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Ethanol; Female; Fruit; Gastric Acid; Gastric Mucosa; Glutathione; H(+)-K(+)-Exchanging ATPase; Methylene Chloride; Mice; Mucus; Phytotherapy; Piper; Piperidones; Plant Extracts; Rabbits; Rats; Rats, Wistar; Solvents; Stomach Ulcer

2013
Synthesis, anticancer, and antibacterial activities of piplartine derivatives on cell cycle regulation and growth inhibition.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:6

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Cell Cycle; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Piper; Piperidones; Pseudomonas aeruginosa; Staphylococcus aureus

2013
Schistosomiasis control using piplartine against Biomphalaria glabrata at different developmental stages.
    PLoS neglected tropical diseases, 2013, Volume: 7, Issue:6

    Topics: Animals; Antiparasitic Agents; Biological Assay; Biomphalaria; Magnetic Resonance Spectroscopy; Piper; Piperidones; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Survival Analysis

2013
Cytotoxicity of piperamides towards Aedes aegypti (Diptera: Culicidae).
    Journal of medical entomology, 2014, Volume: 51, Issue:2

    Topics: Aedes; Animals; Dioxolanes; Insecticides; Larva; Lethal Dose 50; Piper; Piperidones; Plant Extracts

2014
Antitumour efficacy of Piper tuberculatum and piplartine based on the hollow fiber assay.
    Planta medica, 2015, Volume: 81, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Mice, Inbred BALB C; Mice, Nude; Piper; Piperidones; Plant Extracts; Plant Roots; Polyvinyls

2015
Molecular binding mechanism of 5-hydroxy-1-methylpiperidin-2-one with human serum albumin.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:3

    Topics: Binding Sites; Circular Dichroism; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Multiprotein Complexes; Piper; Piperidones; Plants, Medicinal; Protein Binding; Serum Albumin, Human; Spectroscopy, Fourier Transform Infrared

2018
Antiparasitic activity of piplartine (piperlongumine) in a mouse model of schistosomiasis.
    Acta tropica, 2020, Volume: 205

    Topics: Animals; Disease Models, Animal; Female; Mice; Piper; Piperidones; Schistosomiasis mansoni; Schistosomicides

2020
Biological and physical approaches on the role of piplartine (piperlongumine) in cancer.
    Scientific reports, 2020, 12-17, Volume: 10, Issue:1

    Topics: Alkaloids; Annexin A1; Anti-Inflammatory Agents; Antineoplastic Agents; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CCL2; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Neoplasm Invasiveness; Neoplasms; Piper; Piperidones; Tumor Microenvironment

2020