2-piperidone has been researched along with lactimidomycin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 14 (70.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hatori, M; Kamei, H; Komiyama, N; Konishi, M; Moriyama, T; Nishiyama, Y; Oki, T; Sawada, Y; Sugawara, K; Toda, S | 1 |
| Jiang, H; Ju, J; Lim, SK; Seo, JW; Shen, B | 1 |
| Her, Y; Ju, J; Lim, SK; Seo, JW; Shen, B | 1 |
| Hoffmann, FM; Ju, J; Lim, SK; Peters, NR; Rajski, SR; Seo, JW; Shen, B | 2 |
| Fürstner, A; Micoine, K | 1 |
| Fürstner, A; Gallenkamp, D | 1 |
| Huang, SX; Lee, S; Liu, B; Qian, SB; Shen, B | 1 |
| Kaji, A; Kaji, H; Kurata, S; Liu, JO; Shen, B; Takeuchi, N | 1 |
| Fürstner, A; Lam, MH; Llaveria, J; Loganzo, F; Maderna, A; Micoine, K; Persich, P | 1 |
| Larsen, BJ; Nagorny, P; Sun, Z | 1 |
| Kuwahara, S; Nagasawa, T | 1 |
| Garreau de Loubresse, N; Holtkamp, W; Prokhorova, I; Rodnina, MV; Yusupov, M; Yusupova, G | 1 |
| Cleveland, J; Farnet, CM; Jiang, H; Ju, J; Kwong, T; Lim, SK; Lohman, JR; Ma, M; Seo, JW; Shen, B; Yang, C; Zazopoulos, E | 1 |
| Georg, GI; Li, W | 1 |
| Pan, G; Shen, B; Xiang, W; Yan, Y; Yang, D; Zhang, B | 1 |
| Khomutnyk, Y; Lachacz, E; Larsen, BJ; Nagorny, P; Soellner, MB; Sun, Z | 1 |
| Carocci, M; Yang, PL | 1 |
| Brar, GA; Cheng, Z | 1 |
| Gerashchenko, MV; Gladyshev, VN; Peterfi, Z; Yim, SH | 1 |
20 other study(ies) available for 2-piperidone and lactimidomycin
| Article | Year |
|---|---|
Lactimidomycin, a new glutarimide group antibiotic. Production, isolation, structure and biological activity.
Topics: Animals; Antibiotics, Antineoplastic; Antifungal Agents; Female; Macrolides; Magnetic Resonance Spectroscopy; Male; Mice; Microbial Sensitivity Tests; Neoplasms, Experimental; Piperidones; Streptomyces | 1992 |
Iso-migrastatin congeners from Streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and NK30424 scaffolds.
Topics: Antibiotics, Antineoplastic; Lactones; Macrolides; Magnetic Resonance Spectroscopy; Molecular Structure; Piperidones; Streptomyces | 2005 |
New lactimidomycin congeners shed insight into lactimidomycin biosynthesis in Streptomyces amphibiosporus.
Topics: Biological Products; Chromatography, High Pressure Liquid; Macrolides; Molecular Structure; Piperidones; Streptomyces | 2007 |
Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency.
Topics: Animals; Antibiotics, Antineoplastic; Cell Movement; Drug Design; Female; Humans; Macrolides; Mice; Molecular Structure; Piperidones; Structure-Activity Relationship | 2008 |
Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.
Topics: Animals; Biological Products; Cell Line, Tumor; Cell Movement; Cell Survival; Humans; Macrolides; Mice; Molecular Structure; Piperidones; Structure-Activity Relationship | 2009 |
Concise total synthesis of the potent translation and cell migration inhibitor lactimidomycin.
Topics: Animals; Cell Movement; Humans; Macrolides; Piperidones; Protein Biosynthesis | 2010 |
Stereoselective synthesis of E,Z-configured 1,3-dienes by ring-closing metathesis. Application to the total synthesis of lactimidomycin.
Topics: Alkenes; Macrolides; Piperidones; Stereoisomerism; Substrate Specificity | 2011 |
Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution.
Topics: Animals; Codon, Initiator; Cycloheximide; DNA Primers; DNA, Complementary; HEK293 Cells; Humans; Immunoblotting; Macrolides; Mice; Peptide Chain Initiation, Translational; Piperidones; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Ribosomes; RNA, Messenger; Sequence Analysis, DNA; Transcriptome | 2012 |
Possible steps of complete disassembly of post-termination complex by yeast eEF3 deduced from inhibition by translocation inhibitors.
Topics: Adenosine Triphosphate; Cycloheximide; Fungal Proteins; Fusidic Acid; Indenes; Macrolides; Paromomycin; Peptide Chain Termination, Translational; Peptide Elongation Factors; Peptide Termination Factors; Piperidones; Protein Synthesis Inhibitors; Ribosomes; RNA, Messenger; RNA, Transfer; Saccharomyces cerevisiae | 2013 |
Total syntheses and biological reassessment of lactimidomycin, isomigrastatin and congener glutarimide antibiotics.
Topics: Anti-Bacterial Agents; Cell Movement; Female; Humans; Macrolides; Magnetic Resonance Spectroscopy; Piperidones | 2013 |
Synthesis of eukaryotic translation elongation inhibitor lactimidomycin via Zn(II)-mediated Horner-Wadsworth-Emmons macrocyclization.
Topics: Eukaryotic Initiation Factors; Lactones; Macrolides; Molecular Structure; Piperidones; Stereoisomerism; Zinc | 2013 |
Formal total synthesis of lactimidomycin.
Topics: Lactones; Macrolides; Molecular Structure; Piperidones; Polyketides; Stereoisomerism | 2013 |
Structural basis for the inhibition of the eukaryotic ribosome.
Topics: Base Sequence; Binding Sites; Crystallography, X-Ray; Cycloheximide; Drug Resistance; Eukaryotic Cells; Kinetics; Macrolides; Models, Molecular; Molecular Targeted Therapy; Molecular Weight; Peptide Chain Elongation, Translational; Peptidyl Transferases; Piperidones; Protein Synthesis Inhibitors; Ribosome Subunits, Large, Eukaryotic; Ribosomes; RNA, Messenger; RNA, Transfer; Saccharomyces cerevisiae; Species Specificity; Substrate Specificity | 2014 |
Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.
Topics: Antibiotics, Antineoplastic; Bacterial Proteins; Base Sequence; Bioreactors; Cell Line, Tumor; Cell Survival; Drug Design; Gene Silencing; Humans; Macrolides; Models, Biological; Molecular Sequence Data; Molecular Structure; Multigene Family; Mutant Proteins; Neoplasms; Piperidones; Polyketide Synthases; Polyketides; Protein Engineering; Recombinant Proteins; Stereoisomerism; Streptomyces; Structure-Activity Relationship | 2014 |
A concise formal total synthesis of lactimidomycin.
Topics: Biological Products; Macrolides; Molecular Conformation; Piperidones | 2015 |
Overproduction of lactimidomycin by cross-overexpression of genes encoding Streptomyces antibiotic regulatory proteins.
Topics: Anti-Bacterial Agents; Gene Expression; Genes, Regulator; Macrolides; Piperidones; Streptomyces | 2016 |
Synthesis and Biological Evaluation of Lactimidomycin and Its Analogues.
Topics: Antineoplastic Agents; Biological Factors; Cell Movement; Cyclization; Humans; Lactones; Macrolides; Molecular Structure; Piperidones; Stereoisomerism; Zinc | 2015 |
Lactimidomycin is a broad-spectrum inhibitor of dengue and other RNA viruses.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Dengue Virus; Humans; Macrolides; Peptide Chain Elongation, Translational; Piperidones; RNA Viruses; Vero Cells | 2016 |
Global translation inhibition yields condition-dependent de-repression of ribosome biogenesis mRNAs.
Topics: Cycloheximide; Feedback, Physiological; Gene Expression Regulation, Fungal; Macrolides; Piperidones; Promoter Regions, Genetic; Protein Biosynthesis; Protein Synthesis Inhibitors; Repressor Proteins; Ribosomes; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2019 |
Translation elongation rate varies among organs and decreases with age.
Topics: Aging; Animals; Cluster Analysis; Cranial Sinuses; Cycloheximide; Drug Administration Schedule; Harringtonines; High-Throughput Nucleotide Sequencing; Injections, Intravenous; Kidney; Kinetics; Liver; Longevity; Macrolides; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Orbit; Organ Specificity; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Piperidones; Ribosomes; Tail; Transcriptome | 2021 |