Compounds > 2-piperidone
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2-piperidone and l 691121

2-piperidone has been researched along with l 691121 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldwin, JJ; Buhrow, SA; Butcher, JW; Claremon, DA; Elliott, JM; Habecker, CN; King, SW; Lynch, JJ; Phillips, BT; Selnick, HG1
Ban, Y; Fujii, T; Kawana, K; Konishi, R; Manson, JM; Nakatsuka, T1
Gilbert, JD; Greber, TF; Hichens, M; Olah, TV; Porras, AG1
Appleby, SD; Baskin, EP; Bear, CM; Gehret, JR; Kothstein, T; Lynch, JJ; Sanguinetti, MC; Stupienski, RF; Van der Gaag, LH; Wallace, AA1
Pollard, AE; Spitzer, KW; Yang, L; Zaniboni, M1

Other Studies

5 other study(ies) available for 2-piperidone and l 691121

ArticleYear
4-Oxospiro[benzopyran-2,4'-piperidines] as class III antiarrhythmic agents. Pharmacological studies on 3,4-dihydro-1'-[2-(benzofurazan-5-yl)- ethyl]-6-methanesulfonamidospiro[(2H)-1-benzopyran-2,4'-piperidin]-4-on e (L-691,121).
    Journal of medicinal chemistry, 1992, Oct-16, Volume: 35, Issue:21

    Topics: Animals; Anti-Arrhythmia Agents; Dogs; Piperidones; Spiro Compounds; Structure-Activity Relationship

1992
Embryotoxic effects of L-691,121, a class III antiarrhythmic agent, in rats.
    Archives of toxicology, 1994, Volume: 69, Issue:1

    Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Cardiomegaly; Dose-Response Relationship, Drug; Edema; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fetal Diseases; Gestational Age; Heart Rate, Fetal; Hematoma; Male; Pericardium; Piperidones; Pregnancy; Rats; Rats, Sprague-Dawley; Spiro Compounds

1994
Determination of L-691,121, a new class III antiarrhythmic, and its principal metabolite in plasma by differential radioimmunoassay.
    Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Antibody Specificity; Cross Reactions; Humans; Indicators and Reagents; Ligands; Piperidones; Rabbits; Radioimmunoassay; Spiro Compounds

1994
Cardiac electrophysiologic and antiarrhythmic actions of 3,4-dihydro-1'-[2-(benzofurazan-5-yl) ethyl]-6-methanesulfonamidospiro [(2H)-1-benzopyran-2,4'-piperidin]-4-one HCl (L-691,121), a novel class III agent.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Function; Cells, Cultured; Dogs; Electrophysiology; Ferrets; Guinea Pigs; Heart Atria; Heart Ventricles; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Ischemia; Piperidones; Spiro Compounds; Ventricular Function

1993
Beat-to-beat repolarization variability in ventricular myocytes and its suppression by electrical coupling.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:3

    Topics: Action Potentials; Animals; Cell Communication; Egtazic Acid; Electric Conductivity; Electric Impedance; Electrophysiology; Guinea Pigs; Heart; Heart Rate; Ion Channels; Membrane Potentials; Patch-Clamp Techniques; Piperidones; Spiro Compounds; Tetrodotoxin; Time Factors; Ventricular Function

2000