2-piperidone has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burton, MJ; Collin, L; Gaster, LM; Ho, M; Jones, BJ; Middlemiss, DN; Price, GW; Scott, C; Selkirk, JV; Watson, J | 1 |
| Gaster, LM; Hagan, JJ; Ham, P; Joiner, GF; King, FD; Middlemiss, DN; Mulholland, KR; Price, GW; Roberts, C; Routledge, C; Selkirk, J; Slade, PD; Wyman, PA | 1 |
| Bakker, MH; Bonaventure, P; Cras, P; Langlois, X; Leysen, JE; Luyten, WH; Megens, AA; Serneels, L; Umans, L; Van Leuven, F | 1 |
| Audinot, V; Millan, MJ; Newman-Tancredi, A | 1 |
| Cussac, D; Marini, L; Millan, MJ; Newman-Tancredi, A; Touzard, M | 1 |
| Ahlgren, C; Eriksson, A; Malmberg, A; Ross, SB; Stenfors, C; Tellefors, P | 1 |
| Castro, ME; Mostany, R; Pazos, A | 1 |
| Bartoszyk, GD; Dawson, LA; Hagan, JJ; Hill, M; Hughes, ZA; Langmead, CJ; Middlemiss, DN; Starr, KR | 1 |
8 other study(ies) available for 2-piperidone and guanosine 5'-o-(3-thiotriphosphate)
| Article | Year |
|---|---|
SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.
Topics: Animals; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Piperidones; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Spiro Compounds; Sulfur Radioisotopes | 1998 |
The selective 5-HT1B receptor inverse agonist SB-224289, potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
Topics: Animals; Body Temperature Regulation; Cerebral Cortex; CHO Cells; Cricetinae; Dentate Gyrus; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; Oxadiazoles; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Spiro Compounds; Sumatriptan; Transfection | 1998 |
Humanization of mouse 5-hydroxytryptamine1B receptor gene by homologous recombination: in vitro and in vivo characterization.
Topics: Animals; Benzamides; Benzopyrans; Binding Sites; Brain; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypothermia; In Situ Hybridization; Indoles; Mice; Mice, Transgenic; Motor Activity; Piperidones; Propylamines; Pyridines; Pyrimidines; Pyrroles; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombination, Genetic; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Tritium | 1999 |
Constitutive activity at serotonin 5-HT(1D) receptors: detection by homologous GTPgammaS versus [(35)S]-GTPgammaS binding isotherms.
Topics: Animals; Benzamides; Binding, Competitive; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Methiothepin; Piperidones; Pyridines; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiro Compounds; Sulfur Radioisotopes; Thermodynamics; Transfection | 2001 |
h5-HT(1B) receptor-mediated constitutive Galphai3-protein activation in stably transfected Chinese hamster ovary cells: an antibody capture assay reveals protean efficacy of 5-HT.
Topics: Animals; Benzopyrans; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Dioxins; GTP-Binding Protein gamma Subunits; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Methiothepin; Piperazines; Piperidines; Piperidones; Propylamines; Pyrimidines; Radionuclide Imaging; Receptor, Serotonin, 5-HT1B; Serotonin; Spiro Compounds; Sulfur Radioisotopes | 2003 |
In vitro characterization of AR-A000002, a novel 5-hydroxytryptamine(1B) autoreceptor antagonist.
Topics: Animals; Autoreceptors; Benzamides; Binding, Competitive; Cell Line; Cell Membrane; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; In Vitro Techniques; Indoles; Morpholines; Piperidones; Pyridines; Rabbits; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Saphenous Vein; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Spiro Compounds; Sulfur Radioisotopes; Sumatriptan; Transfection; Tritium; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Autoradiographic characterisation of [35S]GTPgammaS binding stimulation mediated by 5-HT1B receptor in postmortem human brain.
Topics: Aged; Autoradiography; Binding, Competitive; Biphenyl Compounds; Brain; Dipeptides; Drug Interactions; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Oxadiazoles; Piperazines; Piperidones; Postmortem Changes; Protein Binding; Pyridines; Pyrroles; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfur Isotopes | 2005 |
Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzofurans; Benzylamines; Binding, Competitive; Cell Membrane; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Frontal Lobe; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Indoles; Male; Microdialysis; Norepinephrine; Paroxetine; Piperazines; Piperidones; Pyridines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfur Radioisotopes; Time Factors; Tritium; Vilazodone Hydrochloride | 2005 |