Compounds > 2-piperidone
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2-piperidone and brl 15572

2-piperidone has been researched along with brl 15572 in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (33.33)18.2507
2000's6 (33.33)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gaster, L; Hagan, JJ; Hatcher, JP; Jeffrey, P; Middlemiss, DN; Slade, PD1
Brown, AM; Hundeshagen, AG; Kaumann, AJ; Schindler, M; Verheggen, R1
Centurión, D; De Vries, P; Heiligers, JP; Sánchez-López, A; Saxena, PR; Villalón, CM1
Marcoli, M; Maura, G; Munari, C; Raiteri, M; Ruelle, A1
De Vries, P; Heiligers, JP; Saxena, PR; Villalón, CM; Willems, EW1
Heeley, RP; Kirk, A; MacLean, MR; Morecroft, I; Prentice, HM1
Dekeyne, A; Gobert, A; Millan, MJ1
Centurión, D; Sánchez-López, A; Saxena, PR; Villalón, CM1
Arulmani, U; Centurión, D; Sánchez-López, A; Saxena, PR; Vázquez, E; Villalón, CM1
Arulmani, U; Centurión, D; Saxena, PR; Valdivia, LF; Villalón, CM1
Castro, ME; Mostany, R; Pazos, A1
Centurión, D; González-Hernández, A; Lozano-Cuenca, J; Maassenvandenbrink, A; Muñoz-Islas, E; Ramírez-Rosas, MB; Sánchez-López, A; Villalón, CM1
Ribeiro, CA; Silva, SA1
Argüelles, CF; Godínez-Chaparro, B; Granados-Soto, V; López-Santillán, FJ; Villalón, CM1
Cervantes-Durán, C; Granados-Soto, V; Murbartián, J; Quiñonez-Bastidas, GN; Rocha-González, HI1
Chan, KY; Danser, AH; de Vries, R; Dirven, C; Garrelds, IM; Labruijere, S; MaassenVanDenBrink, A; Ramírez Rosas, MB; van den Bogaerdt, A; Villalón, CM1
Anguiano-Robledo, L; Lacivita, E; Leopoldo, M; López-Sánchez, P; Sánchez-Maldonado, C; Terrón, JA1
Coen, A; de Los Monteros-Zuñiga, E; Godínez-Chaparro, B; Izquierdo, T; Mata-Bermudez, A1

Other Studies

18 other study(ies) available for 2-piperidone and brl 15572

ArticleYear
Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig.
    European journal of pharmacology, 1997, Jul-23, Volume: 331, Issue:2-3

    Topics: Animals; Benzamides; Biphenyl Compounds; Body Temperature; Dose-Response Relationship, Drug; Guinea Pigs; Hypothermia; Indoles; Male; Oxadiazoles; Piperazines; Piperidones; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds

1997
5-HT1B receptor-mediated contractions in human temporal artery: evidence from selective antagonists and 5-HT receptor mRNA expression.
    British journal of pharmacology, 1998, Volume: 124, Issue:7

    Topics: Adolescent; Adult; Aged; Base Sequence; Biphenyl Compounds; DNA Primers; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Spiro Compounds; Sumatriptan; Temporal Arteries

1998
The canine external carotid vasoconstrictor 5-HT1 receptor: blockade by 5-HT1B (SB224289), but not by 5-HT1D (BRL15572) receptor antagonists.
    European journal of pharmacology, 1998, Nov-27, Volume: 362, Issue:1

    Topics: Anesthesia; Animals; Biphenyl Compounds; Blood Pressure; Carotid Artery, External; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Ergolines; Heart Rate; Norepinephrine; Piperazines; Piperidones; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiro Compounds; Sumatriptan; Sympathectomy; Vagotomy; Vasoconstriction

1998
Pharmacological diversity between native human 5-HT1B and 5-HT1D receptors sited on different neurons and involved in different functions.
    British journal of pharmacology, 1999, Volume: 126, Issue:3

    Topics: Adult; Aged; Binding Sites; Biphenyl Compounds; Cerebral Cortex; Female; Glutamic Acid; Humans; Male; Middle Aged; Neurons; Oxadiazoles; Piperazines; Piperidones; Potassium Chloride; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiro Compounds; Synaptosomes; Tritium

1999
Investigation of the role of 5-HT1B and 5-HT1D receptors in the sumatriptan-induced constriction of porcine carotid arteriovenous anastomoses.
    British journal of pharmacology, 1999, Volume: 127, Issue:2

    Topics: Animals; Arteriovenous Anastomosis; Biphenyl Compounds; Carotid Arteries; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sumatriptan; Swine; Sympathectomy; Vagotomy; Vasoconstrictor Agents

1999
5-hydroxytryptamine receptors mediating contraction in human small muscular pulmonary arteries: importance of the 5-HT1B receptor.
    British journal of pharmacology, 1999, Volume: 128, Issue:3

    Topics: Base Sequence; Benzamides; Biphenyl Compounds; DNA Primers; Humans; Ketanserin; Muscle Contraction; Piperazines; Piperidones; Pulmonary Artery; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; Serotonin Antagonists; Spiro Compounds

1999
The ability of WAY100,635 to potentiate the neurochemical and functional actions of fluoxetine is enhanced by co-administration of SB224,289, but not BRL15572.
    Neuropharmacology, 2000, Jul-10, Volume: 39, Issue:9

    Topics: Animals; Behavior, Animal; Biphenyl Compounds; Dialysis Solutions; Dopamine; Drug Synergism; Fluoxetine; Frontal Lobe; Head Movements; Male; Norepinephrine; Piperazines; Piperidones; Pyridines; Rats; Rats, Wistar; Serotonin; Serotonin Agents; Spiro Compounds

2000
Unravelling the pharmacological profile of the canine external carotid vasodilator '5-HT1-like' receptors: coexistence of sympatho-inhibitory 5-HT1B and postjunctional 5-HT7 receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1

    Topics: 5-Methoxytryptamine; Acetylcholine; Animals; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Carotid Artery, External; Chromans; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Male; Neuromuscular Junction; Oxadiazoles; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sumatriptan; Sympathetic Nervous System; Vasodilation

2001
Further characterization of the 5-HT1 receptors mediating cardiac sympatho-inhibition in pithed rats: pharmacological correlation with the 5-HT1B and 5-HT1D subtypes.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:2

    Topics: Animals; Biphenyl Compounds; Decerebrate State; Male; Norepinephrine; Oxadiazoles; Piperazines; Piperidones; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Spiro Compounds; Sumatriptan; Sympathomimetics; Tachycardia

2004
5-HT1B receptors, alpha2A/2C- and, to a lesser extent, alpha1-adrenoceptors mediate the external carotid vasoconstriction to ergotamine in vagosympathectomised dogs.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:1

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Carotid Artery, External; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ergotamine; Hypotension; Imidazoles; Indoles; Injections, Intravenous; Isoindoles; Male; Piperazines; Piperidones; Prazosin; Quinolizines; Receptor, Serotonin, 5-HT1B; Receptors, Adrenergic, alpha; Regional Blood Flow; Spiro Compounds; Sympathectomy; Vagotomy; Vasoconstriction; Yohimbine

2004
Autoradiographic characterisation of [35S]GTPgammaS binding stimulation mediated by 5-HT1B receptor in postmortem human brain.
    Neuropharmacology, 2005, Volume: 48, Issue:1

    Topics: Aged; Autoradiography; Binding, Competitive; Biphenyl Compounds; Brain; Dipeptides; Drug Interactions; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Oxadiazoles; Piperazines; Piperidones; Postmortem Changes; Protein Binding; Pyridines; Pyrroles; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfur Isotopes

2005
Spinal sumatriptan inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors.
    European journal of pharmacology, 2009, Aug-01, Volume: 615, Issue:1-3

    Topics: Acetylcholine; Animals; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Capsaicin; Carotid Artery, External; Chromans; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Infusions, Intravenous; Injections, Spinal; Male; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Spiro Compounds; Sumatriptan; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2009
Tachyphylaxis to the sumatriptan-induced contractile effect in the human uterine artery but not in human cerebral blood vessels: pharmacological demonstration of the 5-HT(1B) receptor functionality loss.
    Pharmacology, 2012, Volume: 89, Issue:1-2

    Topics: Adult; Basilar Artery; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Male; Middle Aged; Middle Cerebral Artery; Muscle, Smooth, Vascular; Pindolol; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Spiro Compounds; Sumatriptan; Tachyphylaxis; Time Factors; Uterine Artery

2012
Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats.
    Life sciences, 2013, Jun-13, Volume: 92, Issue:22

    Topics: Acute Pain; Animals; Biphenyl Compounds; Chronic Pain; Dihydroergotamine; Disease Models, Animal; Drug Therapy, Combination; Female; Formaldehyde; Hyperalgesia; Methysergide; Nociceptive Pain; Piperazines; Piperidones; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin Antagonists; Spiro Compounds; Sumatriptan

2013
Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats.
    Life sciences, 2013, Oct-17, Volume: 93, Issue:17

    Topics: Analgesics; Animals; Biphenyl Compounds; Catechin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Glyburide; Hyperalgesia; Indazoles; Methiothepin; Naloxone; NG-Nitroarginine Methyl Ester; Oxadiazoles; Pain Measurement; Piperazines; Piperidones; Pyridines; Quinoxalines; Rats; Spiro Compounds

2013
Cranioselectivity of sumatriptan revisited: pronounced contractions to sumatriptan in small human isolated coronary artery.
    CNS drugs, 2014, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Aged; Biphenyl Compounds; Child; Colforsin; Coronary Vessels; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Male; Meningeal Arteries; Middle Aged; Muscle Contraction; Piperazines; Piperidones; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Spiro Compounds; Sumatriptan; Tissue Culture Techniques; Vasoconstrictor Agents; Vasodilator Agents; Young Adult

2014
GR-127935-sensitive mechanism mediating hypotension in anesthetized rats: are 5-HT5B receptors involved?
    Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:4

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ergotamine; Hypotension; Oxadiazoles; Piperazines; Piperidones; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds

2015
Antiallodynic effect induced by [6]-gingerol in neuropathic rats is mediated by activation of the serotoninergic system and the nitric oxide-cyclic guanosine monophosphate-adenosine triphosphate-sensitive K
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:12

    Topics: Adenosine Triphosphate; Analgesics; Animals; Biphenyl Compounds; Catechols; Cyclic GMP; Fatty Alcohols; Female; Guanosine Monophosphate; Hyperalgesia; Male; Neuralgia; Nitric Oxide; Piperazines; Piperidones; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonergic Neurons; Spiro Compounds

2018