Compounds > 2-piperidone

Page last updated: 2024-08-21

2-piperidone and bortezomib

2-piperidone has been researched along with bortezomib in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	9 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brnjic, S; D'Arcy, P; De Cesare, M; Fryknäs, M; Hassan, M; Larsson, R; Linder, S; Lindsten, K; Olofsson, MH; Perego, P; Sadeghi, B	1
Amerik, AY; Issaenko, OA	1
Brnjic, S; D'Arcy, P; Fryknäs, M; Larsson, R; Linder, S; Mazurkiewicz, M; Sun, C; Zhang, X	1
Anderson, KC; Carrasco, RD; Chauhan, D; D'Arcy, P; Hu, Y; Linder, S; Ray, A; Richardson, P; Tai, YT; Tian, Z; Wang, X	1
Anchoori, RK; Chen, X; Hung, CF; Jiang, R; Karanam, B; Matsui, W; Orlowski, RZ; Peng, S; Roden, RB; Rudek, MA; Tanno, T; Walters, KJ; Wang, JW; Zhao, M	1
Bergqvist, M; Bergström, S; Ekman, S; Gullbo, J; Lennartsson, J; Sooman, L	1
Brnjic, S; D'Arcy, P; Hillert, EK; Linder, S; Mazurkiewicz, M; Mofers, A; Saei, AA; Selvaraju, K; Zhang, X; Zubarev, R	1
Arnér, ES; D'Arcy, P; Linder, S; Saei, AA; Selvaraju, K; Zhang, X; Zubarev, RA	1
Altdörfer, V; Dörfel, D; Fuchs, AR; Grünebach, F; Kropp, KN; Maurer, S; Müller, MR; Rittig, SM; Salih, HR; Schmidt, M; Schnitte, S	1

Other Studies

9 other study(ies) available for 2-piperidone and bortezomib

Article	Year
Inhibition of proteasome deubiquitinating activity as a new cancer therapy. Nature medicine, 2011, Nov-06, Volume: 17, Issue:12 Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Boronic Acids; Bortezomib; Breast Neoplasms; Carboxypeptidases; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Microarray Analysis; Multiple Myeloma; Piperidones; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin; Ubiquitin Thiolesterase; Ubiquitination	2011
Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes. Cell cycle (Georgetown, Tex.), 2012, 05-01, Volume: 11, Issue:9 Topics: Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Boronic Acids; Bortezomib; Breast Neoplasms; Catalytic Domain; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Chalcone; Cyclin D1; Cysteine; Dose-Response Relationship, Drug; Endopeptidases; Female; HeLa Cells; Humans; Ovarian Neoplasms; Phenotype; Piperidones; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitins	2012
Induction of tumor cell apoptosis by a proteasome deubiquitinase inhibitor is associated with oxidative stress. Antioxidants & redox signaling, 2014, Dec-10, Volume: 21, Issue:17 Topics: Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Line, Tumor; Gene Expression Profiling; Humans; Oxidative Stress; Piperidones; Polymerase Chain Reaction; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Reactive Oxygen Species; Transcription, Genetic; Ubiquitin-Specific Proteases	2014
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance. Blood, 2014, Jan-30, Volume: 123, Issue:5 Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Drug Resistance, Neoplasm; Endoplasmic Reticulum Stress; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Multiple Myeloma; Piperidones; Protease Inhibitors; Pyrazines; Ubiquitin Thiolesterase; Up-Regulation	2014
A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer. Cancer cell, 2013, Dec-09, Volume: 24, Issue:6 Topics: Animals; Boronic Acids; Bortezomib; Cell Line, Tumor; Endoplasmic Reticulum Stress; Female; Genes, p53; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms; Piperidones; Proteasome Inhibitors; Pyrazines; Ubiquitination	2013
Synergistic effects of combining proteasome inhibitors with chemotherapeutic drugs in lung cancer cells. BMC research notes, 2017, Nov-02, Volume: 10, Issue:1 Topics: Adenocarcinoma; Antineoplastic Agents; Bortezomib; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Deoxycytidine; Drug Therapy, Combination; Gefitinib; Gemcitabine; Humans; Piperidones; Proteasome Inhibitors; Quinazolines; Small Cell Lung Carcinoma; Vinblastine; Vinorelbine	2017
Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation. Cancer letters, 2019, 04-28, Volume: 448 Topics: Apoptosis; Bortezomib; Cell Death; Cell Line, Tumor; Colonic Neoplasms; Endoplasmic Reticulum Stress; Histone Deacetylase Inhibitors; Humans; Piperidones; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Ubiquitin	2019
Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug. Biochimie, 2019, Volume: 162 Topics: Antineoplastic Agents; Auranofin; Bortezomib; Drug Repositioning; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Mitochondria; Oxidative Stress; Piperidones; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Selenoproteins; Thioredoxin Reductase 1; Thioredoxin Reductase 2; Ubiquitin Thiolesterase	2019
The Deubiquitinase Inhibitor b-AP15 and Its Effect on Phenotype and Function of Monocyte-Derived Dendritic Cells. Neoplasia (New York, N.Y.), 2019, Volume: 21, Issue:7 Topics: Apoptosis; Bortezomib; Cell Line, Tumor; Dendritic Cells; Deubiquitinating Enzymes; Enzyme Inhibitors; Humans; Monocytes; Neoplasms; Piperidones; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ubiquitin	2019