Page last updated: 2024-08-21

2-piperidone and 3,5-bis(benzylidene)-4-piperidone

2-piperidone has been researched along with 3,5-bis(benzylidene)-4-piperidone in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's9 (75.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Bandy, B; Das, S; Das, U; Dimmock, JR; Stables, JP1
Chu, Q; Das, U; Dimmock, JR; Kawase, M; Sakagami, H; Selvakumar, P; Sharma, RK; Wang, Q1
Anant, S; Awasthi, V; Lagisetty, P; Sahoo, K; Vilekar, P1
Agashe, H; Awasthi, V; Lagisetty, P; Sahoo, K1
Das, S; Das, U; Dimmock, JR; Gorecki, DK; Iwamoto, S; Kawase, M; Matsuta, T; Molnár, J; Sakagami, H; Serly, J; Umemura, N1
Bandy, B; Das, U; Dimmock, JR; Helal, M; Islam, A; Nazarali, AJ1
Alcorn, J; Das, U; Dimmock, JR; Hickman, MR; Lee, PJ; Leed, SE; Roncal, N; Sciotti, RJ; Singh, RS1
Awasthi, S; Awasthi, V; King, C; Lagisetty, P; Vilekar, P1
Baráth, Z; Csonka, Á; Das, U; Dimmock, JR; Molnár, J; Pati, HN1
Balzarini, J; Das, U; De Clercq, E; Dimmock, JR; Hossain, M; Kawase, M; Sakagami, H; Umemura, N1
Das, S; Das, U; Dimmock, JR; Doroudi, A; Hossain, M; Zhu, J1
Aguilera, RJ; Amano, S; Borrego, EA; Chhikara, A; Das, S; Das, U; Dimmock, JR; Guerena, CD; Hernandez, CR; Roayapalley, PK; Sakagami, H; Satoh, K; Uesawa, Y1

Other Studies

12 other study(ies) available for 2-piperidone and 3,5-bis(benzylidene)-4-piperidone

ArticleYear
N-Aroyl-3,5-bis(benzylidene)-4-piperidones: a novel class of antimycobacterial agents.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Mice; Molecular Structure; Mycobacterium tuberculosis; Piperidones; Rats; Structure-Activity Relationship

2008
3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride: a lead tumor-specific cytotoxin which induces apoptosis and autophagy.
    Bioorganic & medicinal chemistry letters, 2010, Feb-01, Volume: 20, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cytotoxins; Drug Screening Assays, Antitumor; HL-60 Cells; HT29 Cells; Humans; Piperidones; Quantitative Structure-Activity Relationship

2010
CLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Adenocarcinoma; Antineoplastic Agents; Autophagy; Benzylidene Compounds; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Piperidones; Structure-Activity Relationship

2010
Cyclodextrin-mediated entrapment of curcuminoid 4-[3,5-bis(2-chlorobenzylidene-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid] or CLEFMA in liposomes for treatment of xenograft lung tumor in rats.
    Colloids and surfaces. B, Biointerfaces, 2011, Jun-01, Volume: 84, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cyclodextrins; Disease Models, Animal; Drug Delivery Systems; Liposomes; Lung Neoplasms; Piperidones; Rats

2011
Dimeric 3,5-bis(benzylidene)-4-piperidones: a novel cluster of tumour-selective cytotoxins possessing multidrug-resistant properties.
    European journal of medicinal chemistry, 2012, Volume: 51

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dimerization; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; Piperidones

2012
Mitochondrial dysfunction contributes to the cytotoxicity of some 3,5-bis(benzylidene)-4-piperidone derivatives in colon HCT-116 cells.
    Bioorganic & medicinal chemistry letters, 2013, Feb-15, Volume: 23, Issue:4

    Topics: Animals; Colonic Neoplasms; Glutathione; HCT116 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Piperidones; Reactive Oxygen Species

2013
3,5-bis(benzylidene)-4-piperidones and related N-acyl analogs: a novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Animals; Antimalarials; Drug Resistance; Hep G2 Cells; Humans; Liver; Malaria; Malaria, Falciparum; Mice; Piperidones; Plasmodium berghei; Plasmodium falciparum

2013
Antibacterial activity of synthetic curcumin derivatives: 3,5-bis(benzylidene)-4-piperidone (EF24) and EF24-dimer linked via diethylenetriaminepentacetic acid (EF2DTPA).
    Applied biochemistry and biotechnology, 2014, Volume: 172, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Cell Line; Curcumin; Dendritic Cells; Dimerization; Mice; Pentetic Acid; Phagocytosis; Piperidones

2014
1-[3-(2-Hydroxyethylsulfanyl)propanoyl]-3,5-bis(benzylidene)-4-piperidones: A novel cluster of P-glycoprotein dependent multidrug resistance modulators.
    Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Mice; Piperidones; Protein Binding; Structure-Activity Relationship

2016
Tumour-specific cytotoxicity and structure-activity relationships of novel 1-[3-(2-methoxyethylthio)propionyl]-3,5-bis(benzylidene)-4-piperidones.
    Bioorganic & medicinal chemistry, 2016, 05-15, Volume: 24, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Mice; Neoplasms; Piperidones; Structure-Activity Relationship

2016
Novel hybrid molecules of 3,5-bis(benzylidene)-4-piperidones and dichloroacetic acid which demonstrate potent tumour-selective cytotoxicity.
    Bioorganic & medicinal chemistry letters, 2020, 02-01, Volume: 30, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Crystallography, X-Ray; Dichloroacetic Acid; Drug Screening Assays, Antitumor; Humans; Membrane Potential, Mitochondrial; Molecular Conformation; Piperidones; Quantitative Structure-Activity Relationship; Reactive Oxygen Species

2020
Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity.
    Molecules (Basel, Switzerland), 2022, Oct-09, Volume: 27, Issue:19

    Topics: Antineoplastic Agents; Apoptosis; Carbon; Caspase 3; Cell Line, Tumor; Humans; Piperidones

2022