2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one has been researched along with gamma-aminobutyric acid in 21 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (95.24) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albertson, TE; Joy, RM | 1 |
| Cooper, SJ; Estall, LB | 1 |
| Green, S; Hodges, H | 1 |
| Arbilla, S; Langer, SZ; Lista, A | 1 |
| Ebner, J; Ferenci, P; Rzepczynski, D; Zieve, L; Zimmermann, C | 1 |
| Harris, C; Lal, H | 1 |
| Danchev, N | 1 |
| De Deyn, PP; Macdonald, RL | 2 |
| Meiners, BA; Salama, AI | 1 |
| Zharkovskaia, TA; Zharkovskiĭ, AM | 1 |
| Bernasconi, R; Klebs, K; Klein, M; Maitre, L; Marescaux, C; Martin, P; Portet, C; Schmutz, M; Vergnes, M | 1 |
| Baraldi, M; Penne, A; Pinelli, G; Ricci, P; Santi, M; Ventura, E; Zeneroli, ML | 1 |
| Braestrup, C; Honoré, T; Jensen, LH; Kehr, W; Petersen, EN; Schmiechen, R; Schneider, H; Seidelmann, D; Stephens, DN | 1 |
| Brown, CL; Martin, IL | 1 |
| Williams, M | 1 |
| Haefely, W | 2 |
| Brundish, DE; Cash, WD; Czernik, AJ; Granat, FR; Kalinsky, HJ; Lovell, RA; Petrack, B; Psychoyos, S; Rinehart, RK; Tsai, C; Wade, R | 1 |
| Gee, KW; Morelli, M; Yamamura, HI | 1 |
| Gurley, D; White, G | 1 |
3 review(s) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and gamma-aminobutyric acid
| Article | Year |
|---|---|
Behavioural pharmacology of food, water and salt intake in relation to drug actions at benzodiazepine receptors.
Topics: Animals; Anti-Anxiety Agents; Appetite; Appetite Depressants; Benzodiazepines; Benzodiazepinones; Carbolines; Chlordiazepoxide; Chlorides; Choice Behavior; Diazepam; Drinking Behavior; Feeding Behavior; Flumazenil; Food Deprivation; Food Preferences; gamma-Aminobutyric Acid; Ion Channels; Midazolam; Picrotoxin; Punishment; Pyrazoles; Receptors, GABA-A; Satiation; Sodium Chloride; Species Specificity | 1985 |
Anxioselective anxiolytics.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Benzodiazepines; Brain Chemistry; Drug Interactions; Etazolate; gamma-Aminobutyric Acid; Humans; Molecular Weight; Piperazines; Pyrazoles; Pyridazines; Quinolines; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship | 1983 |
Antagonists of benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Binding, Competitive; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Humans; Models, Chemical; Molecular Conformation; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Transmission | 1983 |
18 other study(ies) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and gamma-aminobutyric acid
| Article | Year |
|---|---|
Modification of evoked hippocampal dentate inhibition by diazepam and three antagonists in urethane-anesthetized rats.
Topics: Anesthesia; Animals; Diazepam; Evoked Potentials; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Isoquinolines; Male; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Urethane | 1989 |
Are the effects of benzodiazepines on discrimination and punishment dissociable?
Topics: Amygdala; Animals; Behavior, Animal; Benzodiazepines; Carbolines; Chlordiazepoxide; Discrimination, Psychological; Ethanolamines; Flumazenil; gamma-Aminobutyric Acid; Midazolam; Punishment; Pyrazoles; Rats; Receptors, GABA-A | 1987 |
Modulation of the electrically evoked release of 5-[3H]hydroxytryptamine from rat cerebral cortex: effects of alpidem, CL 218872, and diazepam.
Topics: Animals; Benzodiazepines; Carbolines; Cerebral Cortex; Diazepam; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Monoamine Oxidase Inhibitors; Pargyline; Pyrazoles; Pyridazines; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1988 |
A benzodiazepine antagonist does not alter the course of hepatic encephalopathy or neural gamma-aminobutyric acid (GABA) binding.
Topics: Animals; Benzodiazepines; Brain; Diazepam; gamma-Aminobutyric Acid; Hepatic Artery; Hepatic Encephalopathy; Ischemia; Kinetics; Liver Circulation; Male; Portacaval Shunt, Surgical; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values | 1987 |
Interoceptive stimuli produced by an anxiogenic drug are mimicked by benzodiazepine antagonists in rats pretreated with isoniazid.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Brain Chemistry; Convulsants; Discrimination, Psychological; Flumazenil; gamma-Aminobutyric Acid; Humans; Isoniazid; Male; Pentobarbital; Pentylenetetrazole; Pyrazoles; Rats | 1985 |
[Benzodiazepines and benzodiazepine receptors].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Brain; Flumazenil; gamma-Aminobutyric Acid; Mice; Muscle Relaxants, Central; Pyrazoles; Rats; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Transmission | 1986 |
Effects of non-sedative anxiolytic drugs on responses to GABA and on diazepam-induced enhancement of these responses on mouse neurones in cell culture.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Buspirone; Carbolines; Cells, Cultured; Convulsants; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Quinolines; Spinal Cord | 1988 |
Enhancement of GABA binding by the benzodiazepine partial agonist CGS9896.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Calcium Chloride; Diazepam; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Pyrazoles; Pyridazines; Rats; Receptors, GABA-A | 1985 |
[Antiabstinent action of fenibut and baclofen on a model of abstinence induced by the benzodiazepine receptor antagonist CGS 8216 in rats receiving diazepam].
Topics: Animals; Baclofen; Behavior, Animal; Diazepam; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Isoxazoles; Male; Pyrazoles; Rats; Receptors, GABA-A; Substance Withdrawal Syndrome; Tranquilizing Agents | 1987 |
CGS 9896 and ZK 91296, but not CGS 8216 and RO 15-1788, are pure benzodiazepine receptor antagonists on mouse neurons in culture.
Topics: Animals; Brain; Carbolines; Cells, Cultured; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Receptors, GABA-A; Spinal Cord | 1987 |
Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models.
Topics: Animals; Anticonvulsants; Brain; Diazepam; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Male; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
Supersensitivity of benzodiazepine receptors in hepatic encephalopathy due to fulminant hepatic failure in the rat: reversal by a benzodiazepine antagonist.
Topics: Animals; Benzodiazepines; Brain; Diazepam; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Kinetics; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Evaluation of the beta-carboline ZK 93 426 as a benzodiazepine receptor antagonist.
Topics: Animals; Anticonvulsants; Ataxia; Benzodiazepinones; Binding, Competitive; Carbolines; Diazepam; Discrimination, Psychological; Drinking; Exploratory Behavior; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Mice; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Sleep | 1984 |
Modification of pyrazoloquinolinone affinity by GABA predicts efficacy at the benzodiazepine receptor.
Topics: Animals; Diazepam; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred Strains; Pentylenetetrazole; Pyrazoles; Radioligand Assay; Receptors, GABA-A; Seizures | 1984 |
Antagonists of benzodiazepines: functional aspects.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Carbolines; Chlorides; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channels; Narcotic Antagonists; Parasympathomimetics; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A; Substance-Related Disorders; Xanthines | 1983 |
CGS 8216: receptor binding characteristics of a potent benzodiazepine antagonist.
Topics: Animals; Benzodiazepines; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Temperature; Tritium | 1982 |
The effect of GABA on in vitro binding of two novel non-benzodiazepines, PK 8165 and CGS 8216, to benzodiazepine receptors in the rat brain.
Topics: Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pyrazoles; Quinolines; Rats; Receptors, Drug; Receptors, GABA-A | 1982 |
Benzodiazepine site inverse agonists can selectively inhibit subtypes of the GABAA receptor.
Topics: Animals; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Oocytes; Patch-Clamp Techniques; Pyrazoles; Receptors, GABA-A; Xenopus | 1995 |