2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and diazepam

2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one has been researched along with diazepam in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	57 (89.06)	18.7374
1990's	5 (7.81)	18.2507
2000's	2 (3.13)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adachi, M; Chomei, N; Eigyo, M; Fujishita, T; Kawasaki, K; Matsushita, A; Murata, S; Sasatani, T; Takada, S	1
Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S	1
Kucharik, RF; Lucki, I	1
Dragunow, M	1
Albertson, TE; Joy, RM	1
Carli, M; Prontera, C; Samanin, R	1
Bizière, K; Fournier, M; Keane, P; Santucci, V; Worms, P	1
Cooper, SJ; Estall, LB	1
Eisenberg, RM; Johnson, C	1
Randall, JI; Rodgers, RJ	2
Arbilla, S; Langer, SZ; Lista, A	1
Ebner, J; Ferenci, P; Rzepczynski, D; Zieve, L; Zimmermann, C	1
Bennett, DA	2
Spealman, RD; Wettstein, JG	2
Albertson, TE; Foulke, GE	1
De Deyn, PP; Macdonald, RL	2
Baraldi, M; Penne, A; Pinelli, G; Ricci, P; Santi, M; Zeneroli, ML	1
Kempner, ES; Paul, SM; Schwartz, RD; Skolnick, P; Thomas, JW	1
Caporali, MG; Gatta, F; Lucantoni, D; Massotti, M; Mele, L	1
Shannon, HE; Thompson, WA	1
Meiners, BA; Salama, AI	1
Kulkarni, SK; Kunchandy, J	1
Bender, AS; Hertz, L	1
Zharkovskaia, TA; Zharkovskiĭ, AM	2
Goldstein, JM; Malick, JB; Sutton, EB	1
Martin, WR; McNicholas, LF	1
Katzman, NJ; Shannon, HE	1
Biziere, K; Calassi, R; Chambon, JP; Heaulme, M; Perio, A	1
Sanger, DJ	1
Albertson, TE; Walby, WF	1
Iwasawa, H; Naito, H; Tonoue, T	1
Griffiths, RR; Lamb, RJ	1
Martin, WR; McNicholas, LF; Sloan, JW; Wala, E	1
Bernasconi, R; Klebs, K; Klein, M; Maitre, L; Marescaux, C; Martin, P; Portet, C; Schmutz, M; Vergnes, M	1
Risner, ME; Shannon, HE	1
Kazandjian, A; Spyraki, C; Varonos, D	1
Baraldi, M; Penne, A; Pinelli, G; Ricci, P; Santi, M; Ventura, E; Zeneroli, ML	1
Braestrup, C; Honoré, T; Jensen, LH; Kehr, W; Petersen, EN; Schmiechen, R; Schneider, H; Seidelmann, D; Stephens, DN	1
Brown, C; Jones, B; Martin, I; Oakley, N	1
Mendelson, WB	1
Brown, CL; Martin, IL	1
File, SE; Lister, RG	1
Cherian, S; Martin, WR; McNicholas, LF	1
Herling, S; Shannon, HE	2
Bernard, P; Cassidy, JP; Czernik, AJ; Petrack, B; Yokoyama, N	1
Amato, M; Bizzi, A; Garattini, S; Ricci, MR; Veneroni, E	1
File, SE	1
Davis, T; Mendelson, WB; Paul, SM; Skolnick, P	1
Robertson, HA	1
Barbaz, BS; Bergen, KM; Bernard, PS; Boast, CA	1
Lloyd, HG; Morgan, PF; Stone, TW	1
Schwarz, M; Sontag, KH; Turski, L	1
Schwarz, M; Sontag, KH; Turski, L; Turski, WA	1
Davis, SL; Shannon, HE	1
Cain, M; Cook, J; Paul, S; Schweri, M; Skolnick, P	1
Eisenberg, RM	1
Arilla, E; Martínez, A	1
Arilla-Ferreiro, E; Boyano-Adánez, MC; Izquierdo-Claros, RM; Martínez-Ferrer, A	1

Reviews

3 review(s) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and diazepam

Article	Year
Behavioural pharmacology of food, water and salt intake in relation to drug actions at benzodiazepine receptors. Neuroscience and biobehavioral reviews, 1985,Spring, Volume: 9, Issue:1 Topics: Animals; Anti-Anxiety Agents; Appetite; Appetite Depressants; Benzodiazepines; Benzodiazepinones; Carbolines; Chlordiazepoxide; Chlorides; Choice Behavior; Diazepam; Drinking Behavior; Feeding Behavior; Flumazenil; Food Deprivation; Food Preferences; gamma-Aminobutyric Acid; Ion Channels; Midazolam; Picrotoxin; Punishment; Pyrazoles; Receptors, GABA-A; Satiation; Sodium Chloride; Species Specificity	1985
Pharmacology of the pyrazolo-type compounds: agonist, antagonist and inverse agonist actions. Physiology & behavior, 1987, Volume: 41, Issue:3 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Diazepam; Hypnotics and Sedatives; Muscle Relaxants, Central; Pyrazoles; Rats; Receptors, GABA-A	1987
The neuropharmacology of various diazepam antagonists. Neuropharmacology, 1983, Volume: 22, Issue:12B Topics: Animals; Benzodiazepinones; Caffeine; Carbolines; Diazepam; Flumazenil; Humans; Physostigmine; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A; Theophylline	1983

Other Studies

61 other study(ies) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and diazepam

Article	Year
Synthesis and structure--activity relationships of fused imidazopyridines: a new series of benzodiazepine receptor ligands. Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14 Topics: Animals; Anticonvulsants; Diazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Imidazoles; Ligands; Male; Mice; Pyridines; Quinolines; Rats; Rats, Wistar; Receptors, GABA-A; Structure-Activity Relationship	1996
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach. Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1 Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship	2000
Increased sensitivity to benzodiazepine antagonists in rats following chronic treatment with a low dose of diazepam. Psychopharmacology, 1990, Volume: 102, Issue:3 Topics: Animals; Anti-Anxiety Agents; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Food; Male; Pyrazoles; Rats; Rats, Inbred Strains; Reinforcement Schedule; Reinforcement, Psychology	1990
Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline. Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4 Topics: Adenosine; Aminophylline; Amygdala; Animals; Brain; Carbolines; Diazepam; Flumazenil; Kindling, Neurologic; Male; Picrotoxin; Pyrazoles; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Purinergic; Rolipram; Seizures; Theophylline; Xanthines	1990
Modification of evoked hippocampal dentate inhibition by diazepam and three antagonists in urethane-anesthetized rats. Experimental neurology, 1989, Volume: 106, Issue:2 Topics: Anesthesia; Animals; Diazepam; Evoked Potentials; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Isoquinolines; Male; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Urethane	1989
Effect of 5-HT1A agonists on stress-induced deficit in open field locomotor activity of rats: evidence that this model identifies anxiolytic-like activity. Neuropharmacology, 1989, Volume: 28, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Desipramine; Diazepam; Male; Models, Biological; Motor Activity; Pyrazoles; Rats; Receptors, Serotonin; Stress, Psychological; Tetrahydronaphthalenes	1989
Cerebral-activating (EEG) properties of two inverse agonists and of an antagonist at the benzodiazepine receptor in the rat. Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:1 Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Central Nervous System Stimulants; Chlorpromazine; Diazepam; Electroencephalography; Flumazenil; Imipramine; Male; Pentobarbital; Pyrazoles; Pyridazines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, GABA-A	1989
Effects of beta-carboline-ethyl ester on plasma corticosterone--a parallel with antagonist-precipitated diazepam withdrawal. Life sciences, 1989, Volume: 44, Issue:20 Topics: Animals; Behavior, Animal; Benzodiazepines; Carbolines; Corticosterone; Diazepam; Kinetics; Male; Pyrazoles; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome	1989
Are the analgesic effects of social defeat mediated by benzodiazepine receptors? Physiology & behavior, 1987, Volume: 41, Issue:3 Topics: Analgesia; Animals; Behavior, Animal; Carbolines; Diazepam; Flumazenil; Male; Mice; Mice, Inbred DBA; Pyrazoles; Receptors, GABA-A; Social Behavior	1987
Modulation of the electrically evoked release of 5-[3H]hydroxytryptamine from rat cerebral cortex: effects of alpidem, CL 218872, and diazepam. Journal of neurochemistry, 1988, Volume: 51, Issue:5 Topics: Animals; Benzodiazepines; Carbolines; Cerebral Cortex; Diazepam; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Monoamine Oxidase Inhibitors; Pargyline; Pyrazoles; Pyridazines; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin	1988
A benzodiazepine antagonist does not alter the course of hepatic encephalopathy or neural gamma-aminobutyric acid (GABA) binding. Metabolic brain disease, 1987, Volume: 2, Issue:3 Topics: Animals; Benzodiazepines; Brain; Diazepam; gamma-Aminobutyric Acid; Hepatic Artery; Hepatic Encephalopathy; Ischemia; Kinetics; Liver Circulation; Male; Portacaval Shunt, Surgical; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values	1987
The non-sedating anxiolytic CGS 9896 produces discriminative stimuli that may be related to an anxioselective effect. Life sciences, 1985, Aug-26, Volume: 37, Issue:8 Topics: Animals; Anti-Anxiety Agents; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Meprobamate; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains	1985
Behavioral effects of zopiclone, CL 218,872 and diazepam in squirrel monkeys: antagonism by Ro 15-1788 and CGS 8216. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2 Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepinones; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Piperazines; Pyrazoles; Pyridazines; Saimiri	1986
Interactions of aminophylline and three benzodiazepine compounds with amygdala-kindled seizures in rats. Experimental neurology, 1987, Volume: 97, Issue:3 Topics: Aminophylline; Amygdala; Animals; Anti-Anxiety Agents; Diazepam; Drug Interactions; Flumazenil; Kindling, Neurologic; Male; Pyrazoles; Rats; Rats, Inbred Strains; Seizures	1987
Effects of non-sedative anxiolytic drugs on responses to GABA and on diazepam-induced enhancement of these responses on mouse neurones in cell culture. British journal of pharmacology, 1988, Volume: 95, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Buspirone; Carbolines; Cells, Cultured; Convulsants; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Quinolines; Spinal Cord	1988
Evidence that 2-phenylpyrazolo[4,3-c]-quinolin-3(5H)-one antagonises pharmacological, electrophysiological and biochemical effects of diazepam in rats. Neuropharmacology, 1985, Volume: 24, Issue:2 Topics: Animals; Binding, Competitive; Brain; Cerebral Cortex; Diazepam; Evoked Potentials, Visual; In Vitro Techniques; Male; Motor Activity; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A	1985
Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex. Journal of neurochemistry, 1985, Volume: 45, Issue:1 Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Flumazenil; Flunitrazepam; Ionophores; Male; Molecular Weight; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A	1985
Supraspinal convulsions induced by inverse benzodiazepine agonists in rabbits. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:1 Topics: Animals; Benzodiazepinones; Carbolines; Diazepam; Electroencephalography; Flumazenil; Male; Pyrazoles; Rabbits; Receptors, GABA-A; Seizures	1985
Pyrazoloquinoline benzodiazepine receptor ligands: effects on schedule-controlled behavior in dogs. Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:2 Topics: Animals; Conditioning, Operant; Convulsants; Diazepam; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Ligands; Male; Pyrazoles; Receptors, GABA-A; Reinforcement Schedule	1985
Enhancement of GABA binding by the benzodiazepine partial agonist CGS9896. European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2 Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Calcium Chloride; Diazepam; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Pyrazoles; Pyridazines; Rats; Receptors, GABA-A	1985
Apparent pA2 estimation of benzodiazepine receptor antagonists. Methods and findings in experimental and clinical pharmacology, 1986, Volume: 8, Issue:9 Topics: Animals; Diazepam; Drug Interactions; Female; Flumazenil; Male; Pentylenetetrazole; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures	1986
Dissimilarities between benzodiazepine-binding sites and adenosine uptake sites in astrocytes and neurons in primary cultures. Journal of neuroscience research, 1987, Volume: 17, Issue:2 Topics: Adenosine; Animals; Astrocytes; Benzodiazepines; Binding Sites; Cells, Cultured; Diazepam; Flumazenil; Isoquinolines; Neurons; Pyrazoles; Receptors, GABA-A	1987
[Antiabstinent action of fenibut and baclofen on a model of abstinence induced by the benzodiazepine receptor antagonist CGS 8216 in rats receiving diazepam]. Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:6 Topics: Animals; Baclofen; Behavior, Animal; Diazepam; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Isoxazoles; Male; Pyrazoles; Rats; Receptors, GABA-A; Substance Withdrawal Syndrome; Tranquilizing Agents	1987
CGS 9896 and ZK 91296, but not CGS 8216 and RO 15-1788, are pure benzodiazepine receptor antagonists on mouse neurons in culture. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1 Topics: Animals; Brain; Carbolines; Cells, Cultured; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Receptors, GABA-A; Spinal Cord	1987
Interactions of Ro 15-1788, CGS 8216 and diazepam on head-turning in rats. Life sciences, 1986, Feb-03, Volume: 38, Issue:5 Topics: Animals; Benzodiazepinones; Diazepam; Drug Interactions; Electric Stimulation; Flumazenil; Head; Male; Movement; Muscimol; Pyrazoles; Rats; Rats, Inbred Strains	1986
Benzodiazepine antagonist, CGS-8216, in diazepam- or pentobarbital-dependent and non-dependent rats. Drug and alcohol dependence, 1986, Volume: 17, Issue:4 Topics: Animals; Arousal; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; Pentobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders	1986
CGS 8216: agonist and diazepam-antagonist effects in rodents. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1 Topics: Animals; Ataxia; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Male; Mice; Pentylenetetrazole; Pyrazoles; Rats; Rats, Inbred F344; Reinforcement, Psychology	1986
Evaluation of two anticonvulsant amino-pyridazine derivatives in the conflict test in rats. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2 Topics: Animals; Anticonvulsants; Conflict, Psychological; Diazepam; Flumazenil; Meprobamate; Mice; Papio; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Valproic Acid	1986
Investigation of the actions of the benzodiazepine antagonists Ro 15-1788 and CGS 8216 using the schedule-controlled behavior of rats. Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:3 Topics: Animals; Anxiety; Behavior, Animal; Benzodiazepines; Diazepam; Drug Interactions; Flumazenil; Male; Pyrazoles; Pyridines; Rats; Rats, Inbred Strains; Zolpidem	1986
Effects of the benzodiazepine antagonists RO 15-1788, CGS-8216 and PK-11195 on amygdaloid kindled seizures and the anticonvulsant efficacy of diazepam. Neuropharmacology, 1986, Volume: 25, Issue:11 Topics: Amygdala; Animals; Diazepam; Flumazenil; Isoquinolines; Kindling, Neurologic; Male; Pyrazoles; Rats; Rats, Inbred Strains	1986
Benzodiazepine ligands, nociception and 'defeat' analgesia in male mice. Psychopharmacology, 1987, Volume: 91, Issue:3 Topics: Analgesia; Animals; Appetite Depressants; Benzodiazepines; Carbolines; Chlordiazepoxide; Diazepam; Flumazenil; Male; Mice; Mice, Inbred DBA; Nociceptors; Pyrazoles	1987
Diazepam and endorphin independently inhibit ultrasonic distress calls in rats. European journal of pharmacology, 1987, Oct-06, Volume: 142, Issue:1 Topics: Animals; Convulsants; Depression, Chemical; Diazepam; Endorphins; Flumazenil; Injections, Subcutaneous; Male; Pyrazoles; Rats; Rats, Inbred Strains; Ultrasonics; Vocalization, Animal	1987
Effects of Ro 15-1788 and CGS 8216 in diazepam-dependent baboons. European journal of pharmacology, 1987, Nov-10, Volume: 143, Issue:2 Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Papio; Pyrazoles; Substance Withdrawal Syndrome; Substance-Related Disorders	1987
Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1 Topics: Analysis of Variance; Animals; Diazepam; Dogs; Flumazenil; Nordazepam; Oxazepam; Pyrazoles; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders	1988
Distinctive behavioral effects of the pyrazoloquinoline CGS 8216 in squirrel monkeys. Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:4 Topics: Animals; Behavior, Animal; Benzodiazepines; Clonidine; Diazepam; Flumazenil; Male; Pyrazoles; Saimiri	1988
Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models. Journal of neural transmission, 1988, Volume: 71, Issue:1 Topics: Animals; Anticonvulsants; Brain; Diazepam; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Male; Pyrazoles; Rats; Rats, Inbred Strains	1988
[Characteristics of the abstinence syndrome induced by the administration of the benzodiazepine antagonist CGS 8216 to rats following chronic treatment with diazepam]. Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:9 Topics: Animals; Benzodiazepines; Diazepam; Male; Pyrazoles; Rats; Substance Withdrawal Syndrome	1987
Behavioral effects of CGS 8216 alone, and in combination with diazepam and pentobarbital in dogs. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4 Topics: Administration, Oral; Animals; Conditioning, Operant; Diazepam; Dogs; Drug Interactions; Injections, Intravenous; Pentobarbital; Pyrazoles; Reinforcement Schedule	1986
Diazepam-induced place preference conditioning: appetitive and antiaversive properties. Psychopharmacology, 1985, Volume: 87, Issue:2 Topics: Animals; Appetitive Behavior; Avoidance Learning; Cocaine; Conditioning, Operant; Convulsants; Diazepam; Male; Meprobamate; Naloxone; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Valproic Acid	1985
Supersensitivity of benzodiazepine receptors in hepatic encephalopathy due to fulminant hepatic failure in the rat: reversal by a benzodiazepine antagonist. Clinical science (London, England : 1979), 1984, Volume: 67, Issue:2 Topics: Animals; Benzodiazepines; Brain; Diazepam; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Kinetics; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A	1984
Evaluation of the beta-carboline ZK 93 426 as a benzodiazepine receptor antagonist. Psychopharmacology, 1984, Volume: 83, Issue:3 Topics: Animals; Anticonvulsants; Ataxia; Benzodiazepinones; Binding, Competitive; Carbolines; Diazepam; Discrimination, Psychological; Drinking; Exploratory Behavior; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Mice; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Sleep	1984
In vivo determination of efficacy of pyrazoloquinolinones at the benzodiazepine receptor. European journal of pharmacology, 1984, Aug-03, Volume: 103, Issue:1-2 Topics: Animals; Binding, Competitive; Brain; Convulsants; Diazepam; Flunitrazepam; Male; Mice; Pentylenetetrazole; Pyrazoles; Receptors, GABA-A	1984
The benzodiazepine receptor and sleep. Psychiatric developments, 1984,Autumn, Volume: 2, Issue:3 Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Calcium; Carbolines; Diazepam; Flumazenil; Flurazepam; Humans; Motor Activity; Nifedipine; Phenobarbital; Pyrazoles; Rats; Receptors, GABA-A; Sleep; Synaptosomes	1984
Modification of pyrazoloquinolinone affinity by GABA predicts efficacy at the benzodiazepine receptor. European journal of pharmacology, 1984, Oct-30, Volume: 106, Issue:1 Topics: Animals; Diazepam; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred Strains; Pentylenetetrazole; Pyrazoles; Radioligand Assay; Receptors, GABA-A; Seizures	1984
Quinolines and anxiety: anxiogenic effects of CGS 8216 and partial anxiolytic profile of PK 9084. Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:2 Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Humans; Male; Motor Activity; Pyrazoles; Quinolines; Rats; Social Behavior	1983
Physical dependence on diazepam and lorazepam in the dog. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:3 Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Dogs; Female; Gait; Humans; Lorazepam; Pyrazoles; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Tremor	1983
Discriminative stimulus effects of diazepam in rats: evidence for a maximal effect. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1 Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Cyproheptadine; Diazepam; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Male; Pentobarbital; Phencyclidine; Pyrazoles; Rats	1983
Benzodiazepine receptor ligands with opposing pharmacologic actions. Advances in biochemical psychopharmacology, 1983, Volume: 38 Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Diazepam; Flumazenil; Flunitrazepam; Kinetics; Ligands; Membranes; Models, Psychological; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Temperature	1983
Benzodiazepine receptor antagonists reverse the effect of diazepam on plasma corticosterone in stressed rats. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:2 Topics: Animals; Benzodiazepinones; Corticosterone; Diazepam; Flumazenil; Male; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stress, Physiological	1984
Modification of seizures elicited by the benzodiazepine Ro 5-3663--a comparison with picrotoxin. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:12 Topics: Animals; Benzodiazepinones; Chemical Phenomena; Chemistry; Convulsants; Diazepam; Drug Synergism; Flumazenil; Male; Mice; Picrotoxin; Pyrazoles; Quinolines; Seizures	1984
Do benzodiazepine receptors mediate the anticonflict action of pentobarbital? Life sciences, 1983, May-09, Volume: 32, Issue:19 Topics: Animals; Benzodiazepines; Conflict, Psychological; Diazepam; Male; Pentobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Thirst	1983
Antagonism of the discriminative effects of diazepam by pyrazoloquinolines in rats. European journal of pharmacology, 1983, Aug-19, Volume: 92, Issue:1-2 Topics: Animals; Diazepam; Discrimination Learning; Male; Pyrazoles; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, GABA-A	1983
Evidence for distinct benzodiazepine receptors for anticonvulsant and sedative actions: implications for the treatment of temporal lobe epilepsy. Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6 Topics: Amygdala; Animals; Anticonvulsants; Benzodiazepinones; Diazepam; Epilepsy, Temporal Lobe; Flumazenil; Kindling, Neurologic; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A	1983
Benzodiazepine inhibition of adenosine uptake is not prevented by benzodiazepine antagonists. European journal of pharmacology, 1983, Jan-28, Volume: 87, Issue:1 Topics: Adenosine; Animals; Benzodiazepines; Benzodiazepinones; Brain; Diazepam; Flumazenil; Flurazepam; Hexobendine; In Vitro Techniques; Pyrazoles; Rats; Rats, Inbred Strains; Synaptosomes; Temperature	1983
CGS 8216, Ro 15-1788 and methyl-beta-carboline-3-carboxylate, but not EMD 41717 antagonize the muscle relaxant effect of diazepam in genetically spastic rats. Life sciences, 1984, Oct-01, Volume: 35, Issue:14 Topics: Animals; Benzodiazepinones; Carbolines; Convulsants; Diazepam; Electromyography; Female; Flumazenil; Imidazoles; Kinetics; Male; Muscle Contraction; Muscle Relaxation; Muscle Spasticity; Pyrazoles; Rats; Rats, Mutant Strains	1984
A specific benzodiazepine antagonist CGS 8216 reverses the muscle relaxant effect of diazepam but not that of phenobarbitone. European journal of pharmacology, 1984, Mar-02, Volume: 98, Issue:3-4 Topics: Animals; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electromyography; Female; Male; Muscle Contraction; Muscle Relaxation; Muscles; Phenobarbital; Pyrazoles; Rats; Rats, Mutant Strains	1984
CGS8216 noncompetitively antagonizes the discriminative effects of diazepam in rats. Life sciences, 1984, Jun-25, Volume: 34, Issue:26 Topics: Animals; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Pyrazoles; Rats; Rats, Inbred F344; Time Factors	1984
Blockade of 3-carbomethoxy-beta-carboline induced seizures by diazepam and the benzodiazepine antagonists, Ro 15-1788 and CGS 8216. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:3 Topics: Animals; Benzodiazepinones; Carbolines; Convulsants; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Harmaline; Indoles; Male; Mice; Pyrazoles; Seizures; Tremor	1982
Sound vibration, a non-invasive stress: antagonism by diazepam. Psychopharmacology, 1993, Volume: 110, Issue:4 Topics: Acoustic Stimulation; Animals; Benzodiazepines; Corticosterone; Diazepam; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Stress, Psychological; Vibration	1993
The effect of diazepam and the benzodiazepine antagonist CGS 8216 on the somatostatinergic neuronal system. Neuropharmacology, 1993, Volume: 32, Issue:4 Topics: Animals; Benzodiazepines; Diazepam; Hippocampus; In Vitro Techniques; Kinetics; Neurons; Pyrazoles; Radioimmunoassay; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Somatostatin; Somatostatin; Synaptosomes	1993
Diazepam attenuation of somatostatin binding and effect of somatostatin on accumulation of inositol 1,4,5-trisphosphate in the rat frontoparietal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:2 Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Diazepam; Drug Administration Schedule; Frontal Lobe; GABA-A Receptor Antagonists; Inositol 1,4,5-Trisphosphate; Iodine Radioisotopes; Male; Parietal Lobe; Pyrazoles; Rats; Rats, Wistar; Somatostatin; Synaptosomes; Type C Phospholipases	2000