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2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and cl 218872

2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one has been researched along with cl 218872 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's2 (14.29)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S1
Damgaard, I; Saederup, E; Schousboe, A; Squires, RF1
Arbilla, S; Langer, SZ; Lista, A1
File, SE; Pellow, S; Wilks, L1
Bennett, DA1
File, SE; Pellow, S2
Spealman, RD; Wettstein, JG1
Gardner, CR; James, V1
Meiners, BA; Salama, AI1
DeLorenzo, RJ; Ishiguro, K; Sartorelli, AC; Taft, WC1
Williams, M1
Gee, KW; Yamamura, HI1
Hadingham, KL; Palmer, KJ; Thompson, SA; Wafford, KA; Whiting, PJ1

Reviews

1 review(s) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and cl 218872

ArticleYear
Anxioselective anxiolytics.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:5

    Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Benzodiazepines; Brain Chemistry; Drug Interactions; Etazolate; gamma-Aminobutyric Acid; Humans; Molecular Weight; Piperazines; Pyrazoles; Pyridazines; Quinolines; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship

1983

Other Studies

13 other study(ies) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and cl 218872

ArticleYear
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
    Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1

    Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship

2000
Development of benzodiazepine and picrotoxin (t-butylbicyclophosphorothionate) binding sites in rat cerebellar granule cells in culture.
    Journal of neurochemistry, 1990, Volume: 54, Issue:2

    Topics: Animals; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cells, Cultured; Cerebellum; Flunitrazepam; Granulocytes; Isoxazoles; Pyrazoles; Pyridazines; Pyridines; Rats

1990
Modulation of the electrically evoked release of 5-[3H]hydroxytryptamine from rat cerebral cortex: effects of alpidem, CL 218872, and diazepam.
    Journal of neurochemistry, 1988, Volume: 51, Issue:5

    Topics: Animals; Benzodiazepines; Carbolines; Cerebral Cortex; Diazepam; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Monoamine Oxidase Inhibitors; Pargyline; Pyrazoles; Pyridazines; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin

1988
The sedative effects of CL 218,872, like those of chlordiazepoxide, are reversed by benzodiazepine antagonists.
    Psychopharmacology, 1985, Volume: 85, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepinones; Chlordiazepoxide; Convulsants; Flumazenil; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pyrazoles; Pyridazines

1985
The non-sedating anxiolytic CGS 9896 produces discriminative stimuli that may be related to an anxioselective effect.
    Life sciences, 1985, Aug-26, Volume: 37, Issue:8

    Topics: Animals; Anti-Anxiety Agents; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Meprobamate; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains

1985
Pro- and anti-convulsant drug effects in combination with the convulsant benzodiazepine Ro 5-4864.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:8

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepinones; Carbolines; Convulsants; Drug Interactions; Male; Mice; Mice, Inbred Strains; Pyrazoles; Pyridazines; Quinolines

1985
Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Benzodiazepinones; Buspirone; Carbolines; Convulsants; Exploratory Behavior; Flumazenil; Male; Pyrazoles; Pyridazines; Pyrimidines; Quinolines; Rats

1986
Behavioral effects of zopiclone, CL 218,872 and diazepam in squirrel monkeys: antagonism by Ro 15-1788 and CGS 8216.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepinones; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Piperazines; Pyrazoles; Pyridazines; Saimiri

1986
Actions and interactions of benzodiazepine agonists, antagonists and inverse agonists on suprahyoid muscle twitching.
    European journal of pharmacology, 1985, Jul-17, Volume: 113, Issue:2

    Topics: Amphetamine; Animals; Benzodiazepines; Carbolines; In Vitro Techniques; Male; Muscle Contraction; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A

1985
Enhancement of GABA binding by the benzodiazepine partial agonist CGS9896.
    European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Calcium Chloride; Diazepam; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Pyrazoles; Pyridazines; Rats; Receptors, GABA-A

1985
The role of benzodiazepine receptors in the induction of differentiation of HL-60 leukemia cells by benzodiazepines and purines.
    Journal of cellular physiology, 1987, Volume: 131, Issue:2

    Topics: Benzodiazepines; Benzodiazepinones; Cell Differentiation; Cell Line; Humans; Isoquinolines; Leukemia, Myeloid, Acute; Purines; Pyrazoles; Pyridazines; Receptors, GABA-A

1987
Selective anxiolytics: are the actions related to partial "agonist" activity or a preferential affinity for benzodiazepine receptor subtypes?
    Advances in biochemical psychopharmacology, 1983, Volume: 38

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Cerebral Cortex; Drug Interactions; Flunitrazepam; Male; Postural Balance; Pyrazoles; Pyridazines; Quinolines; Rats; Receptors, Cell Surface; Receptors, GABA-A; Reflex; Temperature

1983
Expression and pharmacology of human GABAA receptors containing gamma 3 subunits.
    European journal of pharmacology, 1995, Nov-30, Volume: 291, Issue:3

    Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Base Sequence; Benzodiazepines; Benzodiazepinones; Carbolines; Flumazenil; Flunitrazepam; GABA Modulators; Humans; Molecular Sequence Data; Pyrazoles; Pyridazines; Pyridines; Receptors, GABA-A; Recombinant Proteins; Sequence Homology, Amino Acid; Triazolam; Xenopus; Zolpidem

1995