2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one has been researched along with 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (84.21) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bianchi, M; Fumagalli, P; Mantegazza, P; Panerai, AE; Rovati, LC; Sacerdote, P | 1 |
| Randall, JI; Rodgers, RJ | 1 |
| Bennett, DA | 2 |
| Boast, CA; Simke, JP; Snowhill, EW | 1 |
| De Deyn, PP; Macdonald, RL | 2 |
| Shannon, HE; Thompson, WA | 1 |
| Meiners, BA; Salama, AI | 1 |
| Bernasconi, R; Klebs, K; Klein, M; Maitre, L; Marescaux, C; Martin, P; Portet, C; Schmutz, M; Vergnes, M | 1 |
| Bernard, PS; Liebman, JM; Pastor, G | 1 |
| Brown, C; Jones, B; Martin, I; Oakley, N | 1 |
| File, SE; Greenblatt, DJ; Lister, RG | 1 |
| Brown, CL; Martin, IL | 1 |
| Williams, M | 1 |
| Bernard, P; Cassidy, JP; Czernik, AJ; Petrack, B; Yokoyama, N | 1 |
| Herling, S; Shannon, HE | 1 |
| Biggio, G; Carotti, A; Carrieri, A; Cinone, N; Maciocco, A; Massarelli, P; Nencini, C; Pellerano, C; Savini, L; Tuligi, G | 1 |
| Loew, GH; Maguire, PA; Perez, JJ; Schove, LT | 1 |
2 review(s) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one
| Article | Year |
|---|---|
Pharmacology of the pyrazolo-type compounds: agonist, antagonist and inverse agonist actions.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Diazepam; Hypnotics and Sedatives; Muscle Relaxants, Central; Pyrazoles; Rats; Receptors, GABA-A | 1987 |
Anxioselective anxiolytics.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Benzodiazepines; Brain Chemistry; Drug Interactions; Etazolate; gamma-Aminobutyric Acid; Humans; Molecular Weight; Piperazines; Pyrazoles; Pyridazines; Quinolines; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship | 1983 |
17 other study(ies) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and 2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3h)-one
| Article | Year |
|---|---|
Benzodiazepines and their antagonists interfere with opioid-dependent stress-induced analgesia.
Topics: Analgesia; Animals; Benzodiazepines; Drug Interactions; Electroshock; Flumazenil; In Vitro Techniques; Male; Mesencephalon; Naloxone; Pain; Pyrazoles; Rats; Rats, Inbred Strains; Sensory Thresholds; Stress, Physiological | 1990 |
Are the analgesic effects of social defeat mediated by benzodiazepine receptors?
Topics: Analgesia; Animals; Behavior, Animal; Carbolines; Diazepam; Flumazenil; Male; Mice; Mice, Inbred DBA; Pyrazoles; Receptors, GABA-A; Social Behavior | 1987 |
The non-sedating anxiolytic CGS 9896 produces discriminative stimuli that may be related to an anxioselective effect.
Topics: Animals; Anti-Anxiety Agents; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Meprobamate; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains | 1985 |
CGS 8216 and CGS 9896, novel pyrazoloquinoline benzodiazepine ligands with benzodiazepine agonist and antagonist properties.
Topics: Animals; Anti-Anxiety Agents; Autoradiography; Brain; Cerebellum; Convulsants; Flunitrazepam; Hippocampus; Male; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Effects of non-sedative anxiolytic drugs on responses to GABA and on diazepam-induced enhancement of these responses on mouse neurones in cell culture.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Buspirone; Carbolines; Cells, Cultured; Convulsants; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Quinolines; Spinal Cord | 1988 |
Pyrazoloquinoline benzodiazepine receptor ligands: effects on schedule-controlled behavior in dogs.
Topics: Animals; Conditioning, Operant; Convulsants; Diazepam; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Ligands; Male; Pyrazoles; Receptors, GABA-A; Reinforcement Schedule | 1985 |
Enhancement of GABA binding by the benzodiazepine partial agonist CGS9896.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Calcium Chloride; Diazepam; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Pyrazoles; Pyridazines; Rats; Receptors, GABA-A | 1985 |
CGS 9896 and ZK 91296, but not CGS 8216 and RO 15-1788, are pure benzodiazepine receptor antagonists on mouse neurons in culture.
Topics: Animals; Brain; Carbolines; Cells, Cultured; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Receptors, GABA-A; Spinal Cord | 1987 |
Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models.
Topics: Animals; Anticonvulsants; Brain; Diazepam; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Male; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
CGS 8216, a benzodiazepine antagonist, reduces food intake in food-deprived rats.
Topics: Administration, Oral; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Eating; Food Deprivation; Injections, Intraperitoneal; Male; Pyrazoles; Rats; Rats, Inbred Strains | 1986 |
In vivo determination of efficacy of pyrazoloquinolinones at the benzodiazepine receptor.
Topics: Animals; Binding, Competitive; Brain; Convulsants; Diazepam; Flunitrazepam; Male; Mice; Pentylenetetrazole; Pyrazoles; Receptors, GABA-A | 1984 |
A pharmacokinetic study of CGS-8216, a benzodiazepine receptor ligand, in the rat.
Topics: Animals; Behavior, Animal; Brain; Convulsants; Kinetics; Pyrazoles; Rats; Receptors, GABA-A; Spectrophotometry, Ultraviolet | 1984 |
Modification of pyrazoloquinolinone affinity by GABA predicts efficacy at the benzodiazepine receptor.
Topics: Animals; Diazepam; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred Strains; Pentylenetetrazole; Pyrazoles; Radioligand Assay; Receptors, GABA-A; Seizures | 1984 |
Benzodiazepine receptor ligands with opposing pharmacologic actions.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Diazepam; Flumazenil; Flunitrazepam; Kinetics; Ligands; Membranes; Models, Psychological; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Temperature | 1983 |
Antagonism of the discriminative effects of diazepam by pyrazoloquinolines in rats.
Topics: Animals; Diazepam; Discrimination Learning; Male; Pyrazoles; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
High affinity central benzodiazepine receptor ligands: synthesis and structure-activity relationship studies of a new series of pyrazolo[4,3-c]quinolin-3-ones.
Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Culture Techniques; Flunitrazepam; GABA Agonists; GABA Antagonists; Ligands; Magnetic Resonance Spectroscopy; Male; Pyrazoles; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spectrophotometry, Infrared; Structure-Activity Relationship | 1998 |
Comparison of a new class of pyrrole containing benzodiazepine ligands to the pyrazoloquinolinones CGS 9896, 9895, and 8216.
Topics: Animals; Cerebellum; Chemistry, Pharmaceutical; Drug Design; GABA Agonists; GABA-A Receptor Agonists; Ligands; Models, Chemical; Pyrazoles; Rats; Spinal Cord; Structure-Activity Relationship | 1994 |