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2-phenyloxazolone and oxazolone

2-phenyloxazolone has been researched along with oxazolone in 75 studies

Research

Studies (75)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (24.00)	18.7374
1990's	41 (54.67)	18.2507
2000's	10 (13.33)	29.6817
2010's	6 (8.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kaartinen, M; Karjalainen, K; Mäkelä, O; Pelkonen, JL	1
Kaartinen, M; Karjalainen, K; Näkelä, O; Pelkonen, JL	1
David, V; Folk, NL; Maizels, N	1
Gherardi, E; Milstein, C	1
Chan, EY; Lane, PJ; Liu, YJ; MacLennan, IC; Zhang, J	1
Apel, M; Berek, C; Berger, A	1
Alfthan, K; Immonen, T; Kaartinen, M; Knowles, JK; Laukkanen, ML; Sizmann, D; Takkinen, K; Teeri, TT; Vanne, L	1
Cavanagh, J; McManus, S; Riechmann, L	1
Gherardi, E; Gupta, SK; Milstein, C; Rada, C	1
Foote, J; Milstein, C	1
Clackson, T; Griffiths, AD; Hoogenboom, HR; Winter, G	1
McManus, S; Riechmann, L	1
Milstein, C; Neuberger, M; Pannell, R; Sharpe, MJ; Surani, MA	1
Alzari, PM; Boulot, G; Jarvis, JM; Mariuzza, RA; Milstein, C; Poljak, RJ; Spinelli, S	1
Apel, M; Berek, C	1
Holm, L; Kaartinen, M; Knowles, JK; Laaksonen, L; Teeri, TT	1
Kaartinen, M; Mäkelä, O; Solin, ML	1
Kaartinen, M; Mäkelä, O; Pelkonen, J	1
Kaartinen, M; Mäkelä, O	1
Berek, C; Jarvis, JM; Milstein, C	1
Even, J; Kaartinen, M; Mäkelä, O; Pelkonen, E	1
Berek, C; Milstein, C	1
Milstein, C	1
Berek, C; Even, J; Griffiths, GM; Milstein, C	1
Berek, C; Boulot, G; Guillon, V; Jarvis, JM; Mariuzza, RA; Milstein, C; Poljak, RJ	1
Griffiths, GM; Hamlyn, PH; Kaartinen, M; Karjalainen, K; Mäkelä, O; Markham, AF; Milstein, C; Pelkonen, JL	1
Breschkin, AM; McKimm-Breschkin, JL	1
Karjalainen, K; Mäkelä, O; Pelkonen, J; Taylor, BA	1
Ferreira, AM; Hurme, M; Kaartinen, M; Mäkelä, O	2
Binz, H; Günther, E; Laukola, U; Mäkelä, O; Pelkonen, J	1
Litman, GW; Mäkelä, O; Sarvas, HO; Stolen, JS	1
Alzari, PM; Spinelli, S	1
Geiser, M; Kretzschmar, T	1
Berek, C; Ziegner, M	1
Harkki, A; Keränen, S; Knowles, JK; Nyyssönen, E; Penttilä, M; Saloheimo, A	1
Berek, C; Lange, H; Lemke, H	1
Alfthan, K; Keinänen, K; Laukkanen, ML	1
Berek, C; Steinhauser, G; Ziegner, M	1
Gray, D; Källberg, E; Leanderson, T	2
Figini, M; Griffiths, AD; Marks, JD; Winter, G	1
Keinänen, K; Laukkanen, ML; Teeri, TT	1
Holliger, P; Prospero, T; Winter, G	1
Riechmann, L; Weill, M	1
Candussio, A; Laukkanen, ML; Saloheimo, M; Sizmann, D; Takkinen, K; Teeri, TT; Veijola-Bailey, P	1
Jarvis, JM; Lozano, F; Milstein, C; Rada, C	1
Alfthan, K; Immonen, T; Kaartinen, M; Keränen, S; Knowles, JK; Seppälä, I; Sizmann, D; Takkinen, K; Teeri, TT; Vanne, L	1
Alfthan, K; Sizmann, D; Söderlund, H; Takkinen, K; Teeri, TT	1
Gray, D; Jainandunsing, S; Källberg, E; Leanderson, T	1
Lange, H; Lemke, H	1
Holliger, PH; Low, NM; Winter, G	1
Aizawa, M; Haruyama, T; Keinänen, K; Kobatake, E; Laukkanen, ML; Sasakura, H	1
González-Fernández, A; Milstein, C	1
Duncan, AR; FitzGerald, K; Hoogenboom, HR; Mahoney, W; McGuinness, BT; Schuler, P; Walter, G	1
Bertocci, B; Delbos, F; Frey, S; Quint, L; Reynaud, CA; Weill, JC	1
White, HN	1
Andersson, K; Leanderson, T; Wrammert, J	1
Hansen, H; Henningsen, M; Kobarg, J; Lange, H; Lemke, H; Solterbeck, M; Yazynin, S	1
Gray, D; White, H	1
Alfthan, K; Mottershead, DG; Ojala, K; Oker-Blom, C; Takkinen, K	1
Kleinstein, SH; Singh, JP	1
Hansen, H; Lange, H; Lemke, H	1
Aune, R; Aune, TE; Brautaset, T; Ellingsen, TE; Hakvåg, S; Hellebust, H; Nedal, A; Sletta, H; Valla, S	1
Foote, J; O'Hear, CE	1
Butch, AW; Kelly, KA	1
Abe, R; Azuma, T; Banri-Koike, C; Endo, K; Furukawa, K; Murakami, A; Oda, M; Ogawa, S; Osaka, Y; Shimizu, T; Yoshida, M	1
Lange, H; Lemke, H; Menning, H; Tanasa, RI; Trad, A; Weiss, T; Zemlin, M	1
Fozooni, S; Hamidian, H; Tikdari, AM	1
Klein, A; Or-Guil, M; Schuchhardt, J; Sibila, M; Weber, TS; Weiser, AA; Wittenbrink, N; Zuschratter, W	1
Claës, A; Roche, B; Rougeon, F	1
Bhagwat, AS	1
Berek, C; Chu, VT	1
Klein, A; Or-Guil, M; Schuchhardt, J; Weiser, AA; Wittenbrink, N	1
Dong, H; Li, J; Ouyang, L; Song, S; Xu, C; Zhang, H	1

Reviews

2 review(s) available for 2-phenyloxazolone and oxazolone

Article	Year
Mutation drift and repertoire shift in the maturation of the immune response. Immunological reviews, 1987, Volume: 96 Topics: Animals; Antibody Affinity; Antibody Diversity; B-Lymphocytes; Cell Differentiation; Gene Frequency; Immunoglobulin Variable Region; Mice; Mutation; Oxazolone	1987
Structural implications of somatic mutations during the immune response to 2-phenyloxazolone. Research in immunology, 1994, Volume: 145, Issue:1 Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Binding Sites, Antibody; Epitopes; Immunoglobulin Variable Region; Molecular Sequence Data; Mutation; Oxazolone	1994

Other Studies

73 other study(ies) available for 2-phenyloxazolone and oxazolone

Article	Year
A hapten-specific Ir gene. Journal of immunology (Baltimore, Md. : 1950), 1979, Volume: 123, Issue:4 Topics: Animals; Antibody Formation; Chickens; Chromosome Mapping; Dose-Response Relationship, Immunologic; Epitopes; Female; Genes, MHC Class II; H-2 Antigens; Haptens; Major Histocompatibility Complex; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oxazolone; Serum Albumin	1979
Inheritance of antibody specificity V. Anti-2-phenyloxazolone in the mouse. The Journal of experimental medicine, 1978, Dec-01, Volume: 148, Issue:6 Topics: Animals; Antibody Specificity; Female; Haptens; Immunoglobulin Allotypes; Immunoglobulin Idiotypes; Immunologic Memory; Isoelectric Focusing; Mice; Mice, Inbred Strains; Oxazoles; Oxazolone; Species Specificity; Structure-Activity Relationship	1978
Germ line variable regions that match hypermutated sequences in genes encoding murine anti-hapten antibodies. Genetics, 1992, Volume: 132, Issue:3 Topics: Animals; Base Sequence; DNA Probes; Gene Conversion; Gene Rearrangement, B-Lymphocyte; Genes, Immunoglobulin; Genetic Variation; Immunoglobulin Variable Region; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Oxazolone; Sequence Alignment	1992
Original and artificial antibodies. Nature, 1992, May-21, Volume: 357, Issue:6375 Topics: Animals; Antibodies, Monoclonal; B-Lymphocytes; Base Sequence; Cell Fusion; Enzyme-Linked Immunosorbent Assay; Genes, Immunoglobulin; Hybridomas; Immunoglobulin Heavy Chains; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Oxazolone; Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Nucleic Acid	1992
Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. European journal of immunology, 1991, Volume: 21, Issue:12 Topics: Animals; Antigens, T-Independent; B-Lymphocytes; Dinitrobenzenes; Haptens; Hemocyanins; Immunologic Memory; Lipopolysaccharides; Lymphocyte Activation; Lymphocyte Cooperation; Oxazolone; Plasma Cells; Rats; Rats, Inbred Strains; Spleen	1991
Maturation of the immune response in germinal centers. Cell, 1991, Dec-20, Volume: 67, Issue:6 Topics: Amino Acid Sequence; Antibody Affinity; B-Lymphocyte Subsets; Base Sequence; Clone Cells; DNA Mutational Analysis; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Gene Rearrangement, B-Lymphocyte, Light Chain; Genes, Immunoglobulin; Immunoglobulin kappa-Chains; Lectins; Molecular Sequence Data; Oxazolone; Peanut Agglutinin; Sequence Alignment; Spleen	1991
An active single-chain antibody containing a cellulase linker domain is secreted by Escherichia coli. Protein engineering, 1991, Volume: 4, Issue:7 Topics: Amino Acid Sequence; Antibody Specificity; Base Sequence; Cellulose 1,4-beta-Cellobiosidase; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Glycoside Hydrolases; Hydrogen-Ion Concentration; Immunoglobulin G; Molecular Sequence Data; Oxazolone; Protein Conformation; Protein Denaturation; Recombinant Fusion Proteins; Trichoderma	1991
Uniform labeling of a recombinant antibody Fv-fragment with 15N and 13C for heteronuclear NMR spectroscopy. FEBS letters, 1991, Aug-05, Volume: 287, Issue:1-2 Topics: Base Sequence; Carbon Isotopes; Escherichia coli; Gene Expression; Immunoglobulin Fragments; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrogen Isotopes; Oxazolone; Plasmids; Recombinant Proteins; Transformation, Bacterial	1991
Mutation and selection during the secondary response to 2-phenyloxazolone. Proceedings of the National Academy of Sciences of the United States of America, 1991, Jul-01, Volume: 88, Issue:13 Topics: Amino Acid Sequence; Animals; Antibody Diversity; Antibody-Producing Cells; B-Lymphocytes; Base Sequence; Genes, Immunoglobulin; Haptens; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Immunologic Memory; Mice; Molecular Sequence Data; Mutation; Oligonucleotides; Oxazolone; Polymerase Chain Reaction	1991
Kinetic maturation of an immune response. Nature, 1991, Aug-08, Volume: 352, Issue:6335 Topics: Animals; gamma-Aminobutyric Acid; Genes, Immunoglobulin; Haptens; Hybridomas; Immunity; Immunoglobulin Heavy Chains; Immunoglobulin kappa-Chains; Oxazolone	1991
Making antibody fragments using phage display libraries. Nature, 1991, Aug-15, Volume: 352, Issue:6336 Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Affinity; Base Sequence; Chromatography, Affinity; Cloning, Molecular; Gene Library; Genes, Immunoglobulin; Haptens; Immunoglobulin Heavy Chains; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Mice; Molecular Sequence Data; Oxazolone; Polymerase Chain Reaction	1991
Use of 2D NMR, protein engineering, and molecular modeling to study the hapten-binding site of an antibody Fv fragment against 2-phenyloxazolone. Biochemistry, 1991, Jun-18, Volume: 30, Issue:24 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites, Antibody; Cell Line; Escherichia coli; Genes, Immunoglobulin; Haptens; Immunoglobulin Variable Region; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Oxazolone; Protein Conformation; Protein Engineering; Restriction Mapping	1991
Lack of somatic mutation in a kappa light chain transgene. European journal of immunology, 1990, Volume: 20, Issue:6 Topics: Amino Acid Sequence; Animals; Base Sequence; Gene Rearrangement, B-Lymphocyte, Light Chain; Hybridomas; Immunization; Immunoglobulin Heavy Chains; Immunoglobulin kappa-Chains; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oxazolone	1990
Three-dimensional structure determination of an anti-2-phenyloxazolone antibody: the role of somatic mutation and heavy/light chain pairing in the maturation of an immune response. The EMBO journal, 1990, Volume: 9, Issue:12 Topics: Amino Acid Sequence; Antibodies, Monoclonal; Crystallization; Haptens; Immunoglobulin Fab Fragments; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Ligands; Models, Molecular; Molecular Sequence Data; Mutation; Oxazolone; Protein Conformation; X-Ray Diffraction	1990
Somatic mutations in antibodies expressed by germinal centre B cells early after primary immunization. International immunology, 1990, Volume: 2, Issue:9 Topics: Animals; Antibodies; Antibody Diversity; Antigens; B-Lymphocytes; Hybridomas; Immunization; Mice; Mutation; Oxazolone	1990
Molecular modelling study of antigen binding to oxazolone-specific antibodies: the Ox1 idiotypic IgG and its mature variant with increased affinity to 2-phenyloxazolone. Protein engineering, 1990, Volume: 3, Issue:5 Topics: Amino Acid Sequence; Antibody Affinity; Antigen-Antibody Reactions; Antigens; Binding Sites; Haptens; Immunoglobulin G; Immunoglobulin Idiotypes; Models, Molecular; Molecular Sequence Data; Mutation; Oxazoles; Oxazolone; Protein Conformation	1990
'Allelic' forms of immunoglobulin V genes in different strains of mice. The EMBO journal, 1989, Volume: 8, Issue:6 Topics: Alleles; Animals; Antibodies, Monoclonal; Base Sequence; Genes, Immunoglobulin; Haptens; Immunoglobulin Idiotypes; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oxazolone; RNA, Messenger; Species Specificity	1989
Several V genes participate in the early phenyloxazolone response in various combinations. European journal of immunology, 1986, Volume: 16, Issue:1 Topics: Amino Acid Sequence; Animals; Antibody Formation; Base Sequence; Haptens; Immunoglobulin Heavy Chains; Immunoglobulin Idiotypes; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Immunologic Memory; Mice; Oxazoles; Oxazolone; RNA, Messenger	1986
Functional analogues of the VKOx1 gene in different strains of mice: evolutionary conservation but diversity based on V-J joining. Journal of immunology (Baltimore, Md. : 1950), 1987, Mar-01, Volume: 138, Issue:5 Topics: Amino Acid Sequence; Animals; Antibody Diversity; Base Sequence; Biological Evolution; Genes; Immunoglobulin Idiotypes; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Mice; Mice, Inbred Strains; Oxazolone	1987
Activation of memory and virgin B cell clones in hyperimmune animals. European journal of immunology, 1987, Volume: 17, Issue:8 Topics: Amino Acid Sequence; Animals; Antibody Affinity; Antibody Diversity; B-Lymphocytes; Clone Cells; Dose-Response Relationship, Immunologic; Immunoglobulin Heavy Chains; Immunoglobulin kappa-Chains; Immunoglobulin M; Immunoglobulin Variable Region; Immunologic Memory; Lymphocyte Activation; Mice; Mutation; Oxazolone	1987
V genes of the primary antibody response of C57BL/10 mice to the hapten phenyloxazolone. European journal of immunology, 1988, Volume: 18, Issue:7 Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Base Sequence; Genes, Immunoglobulin; Immunoglobulin Heavy Chains; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Sequence Data; Oxazoles; Oxazolone; RNA, Messenger	1988
Diversity and the genesis of high affinity antibodies. Biochemical Society transactions, 1987, Volume: 15, Issue:5 Topics: Animals; Antibodies; Antibody Affinity; Antibody Diversity; Haptens; Immunoglobulin Joining Region; Mutation; Oxazolone	1987
Light chain germ-line genes and the immune response to 2-phenyloxazolone. The EMBO journal, 1985, Dec-16, Volume: 4, Issue:13A Topics: Animals; Antibody Diversity; Cloning, Molecular; DNA; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Mice; Mutation; Oxazoles; Oxazolone	1985
Preliminary crystallographic study of the Fab fragments of two monoclonal anti-2-phenyloxazolone antibodies. The Journal of biological chemistry, 1985, Aug-25, Volume: 260, Issue:18 Topics: Animals; Antibodies, Monoclonal; Crystallization; Haptens; Immunoglobulin Fab Fragments; Mice; Oxazoles; Oxazolone; Protein Conformation; X-Ray Diffraction	1985
Anti-oxazolone hybridomas and the structure of the oxazolone idiotype. Journal of immunology (Baltimore, Md. : 1950), 1983, Volume: 130, Issue:2 Topics: Amino Acid Sequence; Animals; Antibody Formation; Chemical Phenomena; Chemistry; Hybridomas; Immunoglobulin Heavy Chains; Immunoglobulin Idiotypes; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Oxazoles; Oxazolone; RNA, Messenger	1983
Anti-oxazolone hybridomas and strain distribution of the oxazolone idiotype. Scandinavian journal of immunology, 1983, Volume: 18, Issue:5 Topics: Animals; Antibodies, Anti-Idiotypic; Antibody Specificity; Ascitic Fluid; Binding Sites, Antibody; Binding, Competitive; Cross Reactions; Hybridomas; Immune Sera; Immunoglobulin Idiotypes; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Oxazoles; Oxazolone; Species Specificity	1983
Map position of Igh-Oxa gene within the Igh region of the DBA/2 mouse strain. Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 129, Issue:1 Topics: Animals; Antibodies, Anti-Idiotypic; Binding Sites, Antibody; Chromosome Mapping; Crossing Over, Genetic; Female; Haploidy; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Oxazoles; Oxazolone; Recombination, Genetic	1982
Fine-specificity of the immune response to oxazolones. II. Cytolytic T cells. Journal of immunology (Baltimore, Md. : 1950), 1981, Volume: 127, Issue:6 Topics: Animals; Cytotoxicity, Immunologic; Female; Haptens; Immunity, Cellular; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Oxazolone; Receptors, Antigen, T-Cell; T-Lymphocytes	1981
An immunoglobulin V gene polymorphism in the rat. European journal of immunology, 1982, Volume: 12, Issue:3 Topics: Animals; Antibodies; Crosses, Genetic; Female; Genes; Immunization; Immunoelectrophoresis; Immunoglobulin Idiotypes; Male; Oxazolone; Polymorphism, Genetic; Rats; Rats, Inbred Strains	1982
The range and fine specificity of the anti-hapten immune response: phylogenetic studies. Journal of immunogenetics, 1982, Volume: 9, Issue:6 Topics: Animals; Antibody Diversity; Antibody Formation; Antibody Specificity; Female; Fishes; Haptens; Male; Oxazolone; Phylogeny; Sharks	1982
Fine-specificity of the immune response to oxazolone. I. Contact sensitivity and early antibodies. Journal of immunology (Baltimore, Md. : 1950), 1981, Volume: 127, Issue:6 Topics: Animals; Antibody Formation; Antibody Specificity; Cyclophosphamide; Dermatitis, Contact; Female; Hypersensitivity, Delayed; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Oxazoles; Oxazolone; Piperazines; Time Factors	1981
Evaluation of antibodies fused to minor coat protein III and major coat protein VIII of bacteriophage M13. Gene, 1995, Mar-21, Volume: 155, Issue:1 Topics: Amino Acid Sequence; Antibodies; Bacteriophage M13; Blotting, Western; Capsid; Capsid Proteins; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Immunoglobulin Fragments; Membrane Proteins; Molecular Sequence Data; Oxazolone; Recombinant Fusion Proteins	1995
Analysis of germinal centres in the immune response to oxazolone. Advances in experimental medicine and biology, 1994, Volume: 355 Topics: Animals; Antibody Affinity; Chickens; Clone Cells; DNA; Gene Rearrangement, B-Lymphocyte; Immunization; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Lymphocyte Activation; Lymphocyte Cooperation; Mice; Mice, Inbred BALB C; Oxazolone; Plasma Cells; Polymerase Chain Reaction; Serum Albumin; Spleen; T-Lymphocyte Subsets	1994
Efficient production of antibody fragments by the filamentous fungus Trichoderma reesei. Bio/technology (Nature Publishing Company), 1993, Volume: 11, Issue:5 Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cellulase; Endopeptidases; Genetic Engineering; Genetic Vectors; Immunoglobulin Fab Fragments; Immunoglobulin G; Mice; Molecular Sequence Data; Oxazolone; Plasmids; Recombinant Fusion Proteins; Transfection; Trichoderma	1993
Maternal immunization modulates the primary immune response to 2-phenyl-oxazolone in BALB/c mice. European journal of immunology, 1994, Volume: 24, Issue:12 Topics: Animals; Antibody Affinity; Antibody Formation; Female; Immunity, Maternally-Acquired; Immunoglobulin G; Immunoglobulin M; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Oxazolone; Pregnancy; Serum Albumin	1994
Functional immunoliposomes harboring a biosynthetically lipid-tagged single-chain antibody. Biochemistry, 1994, Sep-27, Volume: 33, Issue:38 Topics: Antibodies; Base Sequence; Drug Delivery Systems; Escherichia coli; Haptens; Lipoproteins; Liposomes; Molecular Sequence Data; Oxazolone; Protein Engineering; Recombinant Fusion Proteins	1994
Development of antibody diversity in single germinal centers: selective expansion of high-affinity variants. European journal of immunology, 1994, Volume: 24, Issue:10 Topics: Amino Acid Sequence; Animals; Antibody Affinity; Antibody Diversity; B-Lymphocytes; Base Sequence; Clone Cells; DNA Primers; Gene Rearrangement, B-Lymphocyte, Light Chain; Genes, Immunoglobulin; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Oxazolone; Sequence Alignment; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Spleen	1994
Kinetics of somatic mutation in lymph node germinal centres. Scandinavian journal of immunology, 1994, Volume: 40, Issue:5 Topics: Animals; Apoptosis; B-Lymphocytes; Base Sequence; Cells, Cultured; DNA; Gene Rearrangement, B-Lymphocyte; Haptens; Histocompatibility Antigens Class II; Immunoenzyme Techniques; Immunoglobulin kappa-Chains; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Transgenic; Molecular Sequence Data; Mutation; Oxazolone; Spleen	1994
In vitro assembly of repertoires of antibody chains on the surface of phage by renaturation. Journal of molecular biology, 1994, May-27, Volume: 239, Issue:1 Topics: Amino Acid Sequence; Animals; Antibody Affinity; Antibody Diversity; Base Sequence; Binding Sites, Antibody; Cloning, Molecular; Coliphages; Gene Library; Genes, Immunoglobulin; Genetic Vectors; Haptens; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Mice; Molecular Sequence Data; Oxazolone; Sequence Analysis, DNA	1994
Lipid-tagged antibodies: bacterial expression and characterization of a lipoprotein-single-chain antibody fusion protein. Protein engineering, 1993, Volume: 6, Issue:4 Topics: Amino Acid Sequence; Antibodies; Base Sequence; Cell Membrane; Escherichia coli; Gene Expression; Immunoglobulin Fragments; Immunoglobulin Variable Region; Lipoproteins; Liposomes; Molecular Sequence Data; Octoxynol; Oxazolone; Palmitic Acid; Palmitic Acids; Polyethylene Glycols; Recombinant Fusion Proteins; Transformation, Bacterial	1993
"Diabodies": small bivalent and bispecific antibody fragments. Proceedings of the National Academy of Sciences of the United States of America, 1993, Jul-15, Volume: 90, Issue:14 Topics: Animals; Antibody Affinity; Antibody Specificity; Base Sequence; Escherichia coli; Genetic Vectors; Haptens; Immunoglobulin Fragments; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Mice; Models, Molecular; Molecular Sequence Data; Muramidase; Oxazolone; Recombinant Proteins	1993
Analysis of somatic mutation activity in multiple V kappa genes involved in the response to 2-phenyl-5-oxazolone. International immunology, 1993, Volume: 5, Issue:6 Topics: Animals; B-Lymphocytes; Base Sequence; DNA; DNA Mutational Analysis; Gene Rearrangement, B-Lymphocyte, Light Chain; Genes, Immunoglobulin; Immunization; Immunoglobulin kappa-Chains; Immunoglobulin Variable Region; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Ovalbumin; Oxazolone; Point Mutation	1993
Phage display and selection of a site-directed randomized single-chain antibody Fv fragment for its affinity improvement. Biochemistry, 1993, Aug-31, Volume: 32, Issue:34 Topics: Amino Acid Sequence; Antibody Specificity; Bacteriophages; Base Sequence; Binding Sites; Cloning, Molecular; Haptens; Immunoglobulin Fragments; Immunoglobulin Variable Region; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oxazolone; Spectrum Analysis	1993
High-level production of an active single-chain Fv fragment in the culture supernatant of Escherichia coli. The Year in immunology, 1993, Volume: 7 Topics: Amino Acid Sequence; Antibodies, Monoclonal; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Cloning, Molecular; Culture Media; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Immunoglobulin Variable Region; Molecular Sequence Data; Oxazolone; Polysaccharide-Lyases; Protein Processing, Post-Translational; Protein Sorting Signals; Recombinant Fusion Proteins; Staphylococcal Protein A	1993
Affinity maturation leads to differential expression of multiple copies of a kappa light-chain transgene. Nature, 1993, May-20, Volume: 363, Issue:6426 Topics: Amino Acid Sequence; Animals; Antibody Affinity; Base Sequence; Cloning, Molecular; DNA; Down-Regulation; Gene Deletion; Gene Expression Regulation; Gene Rearrangement, B-Lymphocyte, Light Chain; Haptens; Hybridomas; Immunoglobulin kappa-Chains; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oxazolone; Rats; Restriction Mapping; RNA, Messenger	1993
Efficient secretion of murine Fab fragments by Escherichia coli is determined by the first constant domain of the heavy chain. Gene, 1993, Jun-30, Volume: 128, Issue:2 Topics: Animals; Antibody Affinity; Cell Membrane; Disulfides; Escherichia coli; Gene Expression Regulation, Bacterial; Haptens; Hot Temperature; Immunoglobulin Constant Regions; Immunoglobulin Fab Fragments; Immunoglobulin G; Immunoglobulin Heavy Chains; Mice; Oxazolone; Protein Conformation; Protein Denaturation; Protein Engineering; Recombinant Fusion Proteins	1993
Properties of a single-chain antibody containing different linker peptides. Protein engineering, 1995, Volume: 8, Issue:7 Topics: Amino Acid Sequence; Antibodies; Antibody Affinity; Cloning, Molecular; Escherichia coli; Haptens; Hydrolysis; Immunoglobulin Fragments; Molecular Sequence Data; Oxazolone; Peptide Fragments; Recombinant Proteins	1995
Somatic mutation of immunoglobulin V genes in vitro. Science (New York, N.Y.), 1996, Mar-01, Volume: 271, Issue:5253 Topics: Amino Acid Sequence; Animals; B-Lymphocytes; Base Sequence; CD40 Antigens; CD40 Ligand; Cells, Cultured; Coculture Techniques; Genes, Immunoglobulin; Haptens; Hybridomas; Immunoglobulin Variable Region; Lipopolysaccharides; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Ovalbumin; Oxazolone; Receptors, Antigen, B-Cell; Th2 Cells; Transfection	1996
Induction of a non-oscillating, long-lasting humoral immune response to an internal network antigen. International immunology, 1996, Volume: 8, Issue:5 Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Haptens; Hemocyanins; Immunoglobulin Idiotypes; Immunoglobulin kappa-Chains; Immunoglobulin M; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Oxazolone; Serum Albumin; Time Factors	1996
Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain. Journal of molecular biology, 1996, Jul-19, Volume: 260, Issue:3 Topics: Amino Acid Sequence; Bacteriophages; Base Sequence; DNA, Recombinant; Escherichia coli; Haptens; Humans; Immunoglobulin Fragments; Molecular Sequence Data; Mutation; Oxazolone; Recombinant Proteins	1996
A fluoroimmunoassay based on immunoliposomes containing genetically engineered lipid-tagged antibody. Analytical chemistry, 1997, Apr-01, Volume: 69, Issue:7 Topics: Binding, Competitive; Fluoresceins; Fluorescent Dyes; Fluoroimmunoassay; Genetic Engineering; Haptens; Liposomes; Oxazolone	1997
Low antigen dose favours selection of somatic mutants with hallmarks of antibody affinity maturation. Immunology, 1998, Volume: 93, Issue:2 Topics: Animals; Antibody Affinity; B-Lymphocytes; Cell Differentiation; Clone Cells; Dose-Response Relationship, Immunologic; Haptens; Immunization; Immunoglobulin Light Chains; Mice; Mice, Inbred BALB C; Mutation; Oxazolone; Polymerase Chain Reaction	1998
Phage diabody repertoires for selection of large numbers of bispecific antibody fragments. Nature biotechnology, 1996, Volume: 14, Issue:9 Topics: Animals; Antibodies, Bispecific; Bacteriophages; Base Sequence; Binding Sites, Antibody; Biotechnology; Cloning, Molecular; Digoxigenin; DNA, Recombinant; Epitopes; Humans; Immunoglobulin Fragments; Mice; Oxazolone; Polymerase Chain Reaction	1996
Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process. Immunity, 1998, Volume: 9, Issue:1 Topics: Adenosine Triphosphatases; Animals; B-Lymphocytes; Base Sequence; Cell Line; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Genes, Immunoglobulin; Germinal Center; Haptens; Mice; Mice, Knockout; Microsatellite Repeats; Mismatch Repair Endonuclease PMS2; Molecular Sequence Data; Mutation; MutS Homolog 2 Protein; Oxazolone; Peyer's Patches; Proteins; Proto-Oncogene Proteins	1998
Restriction-PCR fingerprinting of the immunoglobulin VH repertoire: direct detection of an immune response and global analysis of B cell clonality. European journal of immunology, 1998, Volume: 28, Issue:10 Topics: Amino Acid Sequence; Animals; B-Lymphocytes; Base Sequence; DNA Fingerprinting; DNA, Complementary; Female; Genes, Immunoglobulin; Haptens; Immunoglobulin Heavy Chains; Immunoglobulin Isotypes; Immunoglobulin Variable Region; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Oxazolone; Polymerase Chain Reaction; Restriction Mapping	1998
Repertoire shift occurs during the memory maintenance phase of the immune responses and is not affinity-driven. Scandinavian journal of immunology, 1999, Volume: 49, Issue:1 Topics: Animals; Antibody Affinity; B-Lymphocyte Subsets; Binding Sites, Antibody; Gene Rearrangement, B-Lymphocyte; Genes, Immunoglobulin; Haptens; Immunoglobulin Variable Region; Immunologic Memory; Mice; Mice, Inbred BALB C; Ovalbumin; Oxazolone	1999
Genetic analysis of the maternally induced affinity enhancement in the non-Ox1 idiotypic antibody repertoire of the primary immune response to 2-phenyloxazolone. Scandinavian journal of immunology, 1999, Volume: 49, Issue:1 Topics: Amino Acid Sequence; Animals; Antibodies, Anti-Idiotypic; Antibody Affinity; Base Sequence; Female; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Gene Rearrangement, B-Lymphocyte, Light Chain; Haptens; Immune Sera; Immunization; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Oxazolone; Pregnancy	1999
Analysis of immunoglobulin (Ig) isotype diversity and IgM/D memory in the response to phenyl-oxazolone. The Journal of experimental medicine, 2000, Jun-19, Volume: 191, Issue:12 Topics: Animals; B-Lymphocytes; Female; Immunization; Immunization, Secondary; Immunoglobulin D; Immunoglobulin Heavy Chains; Immunoglobulin Isotypes; Immunoglobulin M; Immunoglobulin Variable Region; Immunologic Memory; Mice; Mice, Inbred BALB C; Oxazolone; Reverse Transcriptase Polymerase Chain Reaction; Spleen	2000
Baculoviral display of functional scFv and synthetic IgG-binding domains. Biochemical and biophysical research communications, 2000, Aug-18, Volume: 275, Issue:1 Topics: Animals; Antibody Specificity; Baculoviridae; Binding Sites, Antibody; Blotting, Western; Carcinoembryonic Antigen; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Immunoglobulin Fragments; Immunoglobulin G; Mice; Oxazolone; Peptide Library; Recombinant Fusion Proteins; Spodoptera; Viral Fusion Proteins	2000
Why are there so few key mutant clones? The influence of stochastic selection and blocking on affinity maturation in the germinal center. International immunology, 2003, Volume: 15, Issue:7 Topics: Amino Acid Sequence; Animals; Antibody Affinity; Base Sequence; Clone Cells; Computer Simulation; Germinal Center; Haptens; Models, Genetic; Models, Immunological; Molecular Sequence Data; Mutation; Nitrophenols; Oxazolone; Phenylacetates; Selection, Genetic; Stochastic Processes	2003
Non-genetic inheritable potential of maternal antibodies. Vaccine, 2003, Jul-28, Volume: 21, Issue:24 Topics: Animals; Antibodies; Antibodies, Monoclonal; Female; Immunoglobulin E; Immunoglobulin G; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Ovomucin; Oxazolone; Phospholipases A; Pregnancy	2003
Broad-host-range plasmid pJB658 can be used for industrial-level production of a secreted host-toxic single-chain antibody fragment in Escherichia coli. Applied and environmental microbiology, 2004, Volume: 70, Issue:12 Topics: Biotechnology; Culture Media; Escherichia coli; Fermentation; Gene Expression Regulation, Bacterial; Genetic Vectors; Haptens; Immunoglobulin Fragments; Oxazolone; Plasmids; Recombination, Genetic	2004
Antibody buffering of a ligand in vivo. Proceedings of the National Academy of Sciences of the United States of America, 2005, Jan-04, Volume: 102, Issue:1 Topics: Antibodies, Monoclonal; gamma-Aminobutyric Acid; Ligands; Oxazolone; Pharmaceutical Preparations; Pharmacokinetics; Time Factors; Tritium	2005
Antigen-specific immunoglobulin E+ B cells are preferentially localized within germinal centres. Immunology, 2007, Volume: 120, Issue:3 Topics: Animals; B-Lymphocytes; Epitopes, B-Lymphocyte; Female; Gene Expression Regulation; Germinal Center; Haptens; Immunoglobulin E; Immunoglobulin G; Mice; Mice, Inbred BALB C; Microdissection; Oxazolone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2007
T cells specific to hapten carrier but not to carrier alone assist in the production of anti-hapten and anti-carrier antibodies. International immunology, 2007, Volume: 19, Issue:10 Topics: Animals; Antibodies; Antibody Formation; Antigens; B-Lymphocytes; CD4-Positive T-Lymphocytes; Haptens; Immunization; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Ovalbumin; Oxazolone	2007
Thymus-independent type 2 antigen induces a long-term IgG-related network memory. Molecular immunology, 2008, Volume: 45, Issue:10 Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Affinity; Antigens, T-Independent; Clone Cells; Cross-Priming; Female; Immunization; Immunoglobulin G; Immunoglobulin Variable Region; Immunologic Memory; Mice; Mice, Inbred BALB C; Models, Immunological; Molecular Sequence Data; Mutation; Oxazolone; Somatic Hypermutation, Immunoglobulin; Thymus Gland; Time Factors	2008
Dodecatungstophosphoric acid (H3PW 12O40), samarium and ruthenium (III) chloride catalyzed synthesis of unsaturated 2-phenyl-5(4H)-oxazolone derivatives under solvent-free conditions. Molecules (Basel, Switzerland), 2008, Dec-18, Volume: 13, Issue:12 Topics: Catalysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxazolone; Phosphoric Acids; Ruthenium Compounds; Samarium; Solvents; Spectrophotometry, Infrared; Time Factors; Tungsten Compounds	2008
Broad volume distributions indicate nonsynchronized growth and suggest sudden collapses of germinal center B cell populations. Journal of immunology (Baltimore, Md. : 1950), 2010, Feb-01, Volume: 184, Issue:3 Topics: Animals; B-Lymphocyte Subsets; Cell Adhesion; Cell Aggregation; Cell Differentiation; Cell Proliferation; Cross-Sectional Studies; Cytokinesis; Germinal Center; Haptens; Mice; Mice, Inbred BALB C; Models, Immunological; Oxazolone; Spleen; Stochastic Processes	2010
Deoxyuridine triphosphate incorporation during somatic hypermutation of mouse VkOx genes after immunization with phenyloxazolone. Journal of immunology (Baltimore, Md. : 1950), 2010, Oct-15, Volume: 185, Issue:8 Topics: Animals; Deoxyuracil Nucleotides; Genes, Immunoglobulin; Immunoglobulin kappa-Chains; Mice; Mice, Inbred BALB C; Oxazolone; Polymerase Chain Reaction; Somatic Hypermutation, Immunoglobulin	2010
Comment on "Deoxyuridine triphosphate incorporation during somatic hypermutation of mouse VkOx genes after immunization with phenyloxazolone". Journal of immunology (Baltimore, Md. : 1950), 2010, Dec-15, Volume: 185, Issue:12 Topics: Animals; Deoxyuracil Nucleotides; Genes, Immunoglobulin; Immunoglobulin kappa-Chains; Mice; Mice, Inbred BALB C; Oxazolone; Polymerase Chain Reaction; Somatic Hypermutation, Immunoglobulin	2010
Immunization induces activation of bone marrow eosinophils required for plasma cell survival. European journal of immunology, 2012, Volume: 42, Issue:1 Topics: Adjuvants, Immunologic; Animals; Bone Marrow Cells; Cell Survival; Eosinophils; Freund's Adjuvant; Immunization; Interleukins; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Oxazolone; Plasma Cells; RNA, Messenger; Tumor Necrosis Factor Ligand Superfamily Member 13; Tumor Necrosis Factor-alpha	2012
Is there a typical germinal center? A large-scale immunohistological study on the cellular composition of germinal centers during the hapten-carrier-driven primary immune response in mice. Journal of immunology (Baltimore, Md. : 1950), 2011, Dec-15, Volume: 187, Issue:12 Topics: Animals; Apoptosis; B-Lymphocyte Subsets; Carrier Proteins; Cell Compartmentation; Cell Proliferation; Clone Cells; Cross-Sectional Studies; Fluorescent Antibody Technique; Germinal Center; Haptens; Immunohistochemistry; Macrophages; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Oxazolone; Serum Albumin; Spleen; T-Lymphocyte Subsets	2011
The discovery of oxazolones-grafted spirooxindoles via three-component diversity oriented synthesis and their preliminary biological evaluation. Bioorganic & medicinal chemistry letters, 2015, Sep-01, Volume: 25, Issue:17 Topics: Antineoplastic Agents; Azo Compounds; Benzylidene Compounds; Cell Line, Tumor; Cycloaddition Reaction; Drug Discovery; Humans; Indoles; Models, Molecular; Neoplasms; Oxazolone; Oxindoles; Pyrrolidines; Spiro Compounds; Stereoisomerism; Thiosemicarbazones	2015