2-phenylglycine and glycine

2-phenylglycine has been researched along with glycine in 74 studies

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19906 (8.11)18.7374
1990's10 (13.51)18.2507
2000's24 (32.43)29.6817
2010's29 (39.19)24.3611
2020's5 (6.76)2.80

Authors

AuthorsStudies
Isobe, A; Izumi, Y; Kanzaki, H; Yamada, H1
Kobow, M; Schulz, E; Sprung, WD1
Bouhadir, K; Clark, CR; DeRuiter, J; Mayfield, CA1
Kobayashi, T; Masuzawa, T; Nagakura, N; Shimizu, T; Yanagihara, Y1
Falzoi, M; Franchini, I; Lucertini, S; Mutti, A; Romanelli, A1
Katzenellenbogen, JA; Kinder, DH1
Bedingfield, JS; Jane, DE; Kemp, MC; Roberts, PJ; Tse, HW; Watkins, JC1
Bastawde, KB; Gaikwad, BG; Gokhale, DV; Jogdand, VV; Joshi, RA; Joshi, RR; Kalkote, UR; Nene, S; Patil, SG; Ravindranathan, T1
Meevootisom, V; Wiyakrutta, S1
Abu-Lafi, S; Turujman, SA2
Bossi, A; Cretich, M; Righetti, PG1
Abbott, NJ; Begley, DJ; Reichel, A1
Svedas, VK; Youshko, MI1
Brady, L; Jones, SD; Liebeschuetz, JW; Mahler, J; Martin, H; Morgan, PJ; Murray, CW; Rimmer, AD; Roscoe, JM; Waszkowycz, B; Welsh, PM; Wilkinson, K; Wylie, WA; Young, SC1
Bossu', E; Cotichini, V; Farina, A; Gostoli, G1
Hoeben, MA; Jauregi, P; Kwant, G; van der Lans, RG; van der Wielen, LA1
Altamura, S; Bazzo, R; Bianchi, E; Cicero, D; Cortese, R; Fattori, D; Ingallinella, P; Koch, U; Pessi, A; Steinkühler, C1
Hatanaka, T; Nabuchi, Y; Ushio, H1
de Vroom, E; Sheldon, RA; Svedas, VK; van Langen, LM; van Rantwijk, F; Youshko, MI1
Liu, JN; Shen, Y; Yi, DN1
Busch, KW; Busch, MA; Fakayode, SO; Swamidoss, IM1
KATSUNO, K; KAWAHARA, S1
KAWAHARA, S; KAWAKAMI, H1
KAWAHARA, S1
Ebert, B; Madsen, U; Vestergaard, HT; Vogensen, SB1
Ishida, T; Kamigauchi, M; Nagata, H; Nishi, H1
Ackermann, J; Alig, L; Banner, DW; Böhm, HJ; Hilpert, K; Kühne, H; Lavé, T; Obst-Sander, U; Riederer, MA; Stahl, M; Tschopp, TB; Weber, L; Wessel, HP; Zbinden, KG1
Alonso, JL; Caminati, W; Cortijo, V; López, JC; Sanz, ME1
Barends, TR; Dijkstra, BW; Janssen, DB; Jekel, PA; Polderman-Tijmes, JJ; Williams, C; Wybenga, G1
Hoeben, MA; Kwant, G; van der Lans, RG; van der Wielen, LA; van Hee, P1
Bovenberg, R; Gunsior, M; Kremer, S; Müller, U; Orf, S; Schipper, D; Sonke, T; Townsend, CA; van Assema, F; Wagemans, A; Wubbolts, M1
Anderson, DJ; Bunnelle, WH; Gopalakrishnan, M; Honore, P; Jarvis, MF; Lee, CH; Lynch, JJ; Marsh, KC; Mortell, KH; Wade, CL; Xu, H; Zhong, C; Zhu, CZ1
Fransson, R; Gossas, T; Helena Danielson, U; Karlén, A; Kerblom, E; Lindeberg, G; Ortqvist, P; Peterson, SD; Sabnis, YA; Sandström, A1
McLeish, MJ; Meevootisom, V; Rojanarata, T; Saehuan, C; Wiyakrutta, S1
Ohashi, T; Shimada, H; Shimizu, S; Takahashi, S; Tani, Y; Yamada, H1
Han, KY; Kim, GS; Kim, HM; Kim, SK; Park, J1
Han, KY; Kim, HM; Kim, SK; Kim, ZH; Park, J1
Arous, N; Caci, E; Caputo, A; Di Duca, M; Fanen, P; Galietta, LJ; Hinzpeter, A; Pedemonte, N; Zegarra-Moran, O1
Butler, JD; Kurth, MJ; Mills, AD; Verkman, AS; Yang, B; Yoo, C1
Akazome, M; Doba, A; Matsumoto, S; Ogura, K1
Almeida Medeiros, I; Barbosa Filho, JM; de Athayde-Filho, PF; de Sousa Luis, JA; dos Anjos, RM; Dos Santos, AF; Freitas Lira, B; Soares de Oliveira, C; Soares Lima de Morais, LC1
Haurena, C; Le Gall, E; Martens, T; Sengmany, S; Troupel, M1
Fan, YB; Lu, HH; Tsai, MC; Tsai, TH; Wang, CL; Wang, HP1
Ogura, Y; Shionoya, M; Tashiro, S; Tsuboyama, K; Tsuboyama, S1
Mast, YJ; Schinko, E; Wohlleben, W1
Chen, JL; Syu, HJ1
Jiao, S; Tang, B; Wang, C; Xie, E; Xu, K; Yao, W1
Cao, Y; Pan, Y; Wang, L; Ye, LJ1
Brittain, HG1
Korczynska, M; Kumaran, D; Narindoshvili, T; Ornelas, A; Ragumani, S; Raushel, FM; Shoichet, BK; Swaminathan, S1
Honma, Y; Takenaka, S; Yoshida, K1
Gontarska, M; Kowalska, T; Sajewicz, M1
Takenaka, S; Tanaka, K; Yoshida, K1
Cai, WW; Qiu, J; Su, EZ; Wang, HL; Wang, W; Wei, DZ1
Kapinos, LE; Lim, RY; Schleicher, KD; Schoch, RL; Wagner, RS1
Ding, ZY; El-Rotail, AA; Gu, ZH; Liu, RX; Liu, SP; Shi, GY; Zhang, L1
Borba, A; Fausto, R; Gómez-Zavaglia, A1
Bai, YP; Fan, CW; Ma, BD; Xu, GC; Xu, JH; Zhang, J1
Nandel, FS; Shafique, M1
Feng, R; Ge, M; Jiang, W; Lu, Y; Ruan, L; Tian, J; Zhao, Y; Zheng, G1
Dastbaravardeh, N; Farmer, ME; Toba, T; Yu, JQ1
Hou, J; Huang, Y; Li, X; Xu, W; Zhang, Y1
Gao, S; Hou, J; Li, J; Li, X; Wang, X; Xu, W; Zang, J; Zhang, Y1
Bennati, M; Diederichsen, U; Halbmair, K; Wegner, J1
Foster, AC; Li, YX; Penjwini, M; Rangel-Diaz, N; Staubli, U; Viswanath, V; Yang, JY1
Ganeshpurkar, A; Kumar, D; Singh, SK1
Kulik, A; Mast, Y; Osipenkov, N1
Chen, F; Chen, X; Fan, L; Li, H; Li, Y; Liu, J; Su, X; Tang, X; Yan, J; Yang, D1
Alcázar, V; Fuentes de Arriba, ÁL; Garrido-González, JJ; Lithgow, AM; Morán, JR; Sanz, F; Simón, L; Turiel, MG1
Handel, F; Hennrich, O; Kocadinc, S; Kulik, A; Mast, Y; Mokeev, V; Moosmann, D; Ort-Winklbauer, R; Osipenkov, N; Sprenger, GA; Youn, JW1
Jia, YY; Kan, YC; Li, X; Shi, HL; Tang, CD; Wang, LF; Xu, JH; Yao, LG1
Yuan, J; Zhu, Y1
Li, R; Liu, Y; Meng, X; Shen, Y; Wang, H; Wei, D; Yang, L1

Other Studies

74 other study(ies) available for 2-phenylglycine and glycine

ArticleYear
Production of benzoylformic acid from phenylglycine by Saccharomycopsis lipolytica.
    Agricultural and biological chemistry, 1990, Volume: 54, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Fructose; Glucose; Glycerol; Glycine; Glyoxylates; Kinetics; Mandelic Acids; Nitrogen; Saccharomycopsis; Stereoisomerism

1990
[The pharmacologic activity of p-substituted DL-2-phenylglycine octyl esters].
    Die Pharmazie, 1990, Volume: 45, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Caprylates; Carrageenan; Edema; Female; Glycine; Guinea Pigs; In Vitro Techniques; Lethal Dose 50; Male; Mice; Parasympatholytics; Rats; Rats, Inbred Strains

1990
Diastereoisomeric derivatization and liquid chromatographic analysis of N-(phenylsulfonyl)-2-phenylglycine aldose reductase inhibitors.
    Journal of chromatographic science, 1990, Volume: 28, Issue:8

    Topics: Aldehyde Reductase; Amides; Anti-Inflammatory Agents, Non-Steroidal; Benzylamines; Chromatography, Liquid; Glycine

1990
Cross-antigenicity between penams and cephems by intradermal skin test and leucocyte migration test in guinea pigs.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:5

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Cell Migration Inhibition; Cephalexin; Cephalosporins; Cephalothin; Cloxacillin; Cross Reactions; Drug Hypersensitivity; Glycine; Guinea Pigs; Hypersensitivity, Delayed; Male; Penicillin G; Skin Tests; Structure-Activity Relationship

1990
Styrene metabolism and striatal dopamine depletion in rabbits.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1985, Volume: 8

    Topics: Animals; Corpus Striatum; Dopamine; Glycine; Glyoxylates; Homovanillic Acid; Male; Mandelic Acids; Nervous System Diseases; Norepinephrine; Rabbits; Styrene; Styrenes; Tyrosine 3-Monooxygenase

1985
Acylamino boronic acids and difluoroborane analogues of amino acids: potent inhibitors of chymotrypsin and elastase.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:12

    Topics: Acylation; Alanine; Amino Acids; Binding, Competitive; Boranes; Boronic Acids; Chemical Phenomena; Chemistry; Chymotrypsin; Glycine; Hydrolysis; Isoleucine; Pancreatic Elastase; Phenylalanine; Structure-Activity Relationship; Valine

1985
Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs).
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Glycine; Inositol Phosphates; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Structure-Activity Relationship

1995
Chemoenzymatic synthesis of D(-)phenylglycine using hydantoinase of Pseudomonas desmolyticum resting cells.
    Enzyme and microbial technology, 1996, Volume: 18, Issue:5

    Topics: Amidohydrolases; Bicarbonates; Biotransformation; Borates; Dipeptides; Glycine; Hydantoins; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Molecular Structure; Nitrous Acid; Phenylacetates; Pseudomonas; Stereoisomerism; Temperature; Urea

1996
A stereo-inverting D-phenylglycine aminotransferase from Pseudomonas stutzeri ST-201: purification, characterization and application for D-phenylglycine synthesis.
    Journal of biotechnology, 1997, Jul-04, Volume: 55, Issue:3

    Topics: Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glutamic Acid; Glycine; Glyoxylates; Hydrogen-Ion Concentration; Isoelectric Point; Ketoglutaric Acids; Mandelic Acids; Molecular Weight; Pseudomonas; Stereoisomerism; Substrate Specificity; Temperature; Transaminases

1997
A chiral HPLC method for the simultaneous separation of configurational isomers of the predominant cis/trans forms of astaxanthin.
    Enantiomer, 1997, Volume: 2, Issue:1

    Topics: Adjuvants, Immunologic; Animals; beta Carotene; Chromatography, High Pressure Liquid; Glycine; Reproducibility of Results; Salmon; Solvents; Stereoisomerism; Xanthophylls

1997
Production of D-phenylglycine from racemic (D,L)-phenylglycine via isoelectrically-trapped penicillin G acylase.
    Biotechnology and bioengineering, 1998, Nov-20, Volume: 60, Issue:4

    Topics: Electrophoresis, Capillary; Enzymes, Immobilized; Glycine; Ion Exchange Resins; Isoelectric Focusing; Isomerism; Kinetics; Penicillin Amidase

1998
Reproducibility of the separation of astaxanthin stereoisomers on Pirkle covalent L-leucine and D-phenylglycine columns.
    Journal of chromatography. A, 1999, Sep-03, Volume: 855, Issue:1

    Topics: beta Carotene; Chromatography, High Pressure Liquid; Glycine; Leucine; Reproducibility of Results; Spectrophotometry, Ultraviolet; Stereoisomerism; Xanthophylls

1999
Carrier-mediated delivery of metabotrophic glutamate receptor ligands to the central nervous system: structural tolerance and potential of the L-system amino acid transporter at the blood-brain barrier.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:1

    Topics: Amino Acid Transport Systems; Animals; Biological Transport; Blood-Brain Barrier; Carrier Proteins; Cell Line; Central Nervous System; Glycine; Histidine; Intracellular Membranes; Ligands; Rats; Receptors, Metabotropic Glutamate

2000
Kinetics of ampicillin synthesis catalyzed by penicillin acylase from E. coli in homogeneous and heterogeneous systems. Quantitative characterization of nucleophile reactivity and mathematical modeling of the process.
    Biochemistry. Biokhimiia, 2000, Volume: 65, Issue:12

    Topics: Ampicillin; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Theoretical; Penicillanic Acid; Penicillin Amidase; Temperature

2000
The design of phenylglycine containing benzamidine carboxamides as potent and selective inhibitors of factor Xa.
    Bioorganic & medicinal chemistry letters, 2001, Mar-12, Volume: 11, Issue:5

    Topics: Benzamidines; Binding Sites; Combinatorial Chemistry Techniques; Crystallography, X-Ray; Drug Design; Factor Xa; Factor Xa Inhibitors; Glycine; Models, Molecular; Molecular Structure; Protein Structure, Tertiary; Software

2001
Determination of optical purity by nonenantioselective LC using CD detection.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 26, Issue:5-6

    Topics: Anisotropy; Calibration; Chlorpheniramine; Chromatography, High Pressure Liquid; Circular Dichroism; Glycine; Reference Standards; Spectrophotometry, Ultraviolet; Stereoisomerism

2001
Recovery of small bioparticles by interfacial partitioning.
    Biotechnology and bioengineering, 2002, May-20, Volume: 78, Issue:4

    Topics: Ampicillin; Butanols; Chromatography, High Pressure Liquid; Crystallization; Emulsions; Feasibility Studies; Glycine; Hexanols; Models, Chemical; Models, Molecular; Particle Size; Penicillins; Phosphates; Polyethylene Glycols; Rheology; Sensitivity and Specificity; Solubility; Solutions; Surface Tension; Water

2002
Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus.
    Biochemistry, 2002, Apr-30, Volume: 41, Issue:17

    Topics: Amino Acid Sequence; Binding Sites; Carrier Proteins; Circular Dichroism; Combinatorial Chemistry Techniques; Computer Simulation; Dicarboxylic Acids; Endopeptidases; Evolution, Molecular; Glycine; Hepacivirus; Intracellular Signaling Peptides and Proteins; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Peptide Library; Serine Endopeptidases; Serine Proteinase Inhibitors; Structure-Activity Relationship; Viral Nonstructural Proteins; Viral Proteins

2002
A study of the substrate specificity of Na+-dependent and Na+-independent neutral amino acid transport systems in dog intestinal brush-border membrane vesicles using L-alanine analogues.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:4

    Topics: Alanine; Amino Acid Transport Systems, Neutral; Animals; Biological Transport, Active; Carbon; Carbon Radioisotopes; Cell Membrane; Cytoplasmic Vesicles; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Intestine, Small; Microvilli; Phenylalanine; Potassium; Sodium Chloride

2002
Penicillin acylase-catalyzed ampicillin synthesis using a pH gradient: a new approach to optimization.
    Biotechnology and bioengineering, 2002, Jun-05, Volume: 78, Issue:5

    Topics: Ampicillin; Catalysis; Cell Line; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Models, Chemical; Penicillanic Acid; Penicillin Amidase; Protons; Quality Control; Sensitivity and Specificity

2002
[Discussion of the application of three-point interaction principle to the phenylglycine racemic compound in IR spectrometry and its enantiomers separation in HPLC].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:8

    Topics: Chromatography, High Pressure Liquid; Glycine; Orosomucoid; Spectrophotometry, Infrared; Stereoisomerism

2002
Determination of the enantiomeric composition of guest molecules by chemometric analysis of the UV-visible spectra of cyclodextrin guest-host complexes.
    Journal of the American Chemical Society, 2003, Feb-19, Volume: 125, Issue:7

    Topics: Cyclodextrins; Glycine; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet; Stereoisomerism

2003
[Studies on the 2-phenylglycine derivatives having antispasmodic activity and their related compounds. IV. Syntheses of 1-2-alkylaminoethyl)-5-arylhydantoins].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1962, Volume: 82

    Topics: Glycine; Hydantoins; Muscle Relaxants, Central; Parasympatholytics

1962
[Studies on the 2-phenylglycine derivatives having antispasmodic activity and their related compounds. III. Syntheses of 3-substituted 2-piperazinones and their 4-methylated compounds].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1962, Volume: 82

    Topics: Glycine; Muscle Relaxants, Central; Parasympatholytics; Piperazines

1962
[Studies on the 2-phenylglycine derivatives having antispasmodic activity and their related compounds. V. Synthesis of 1-(omega-alkylaminoalkyl)-5-aryl (or 2-thienyl) hydantoins].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1962, Volume: 82

    Topics: Glycine; Hydantoins; Muscle Relaxants, Central; Parasympatholytics

1962
Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid.
    European journal of pharmacology, 2004, Mar-19, Volume: 488, Issue:1-3

    Topics: Aminobutyrates; Animals; Calcium Chloride; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Male; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes

2004
Structural scaffold of 18-crown-6 tetracarboxylic acid for optical resolution of chiral amino acid: X-ray crystal analyses and energy calculations of complexes of D- and L-isomers of tyrosine, isoleucine, methionine and phenylglycine.
    Organic & biomolecular chemistry, 2004, Dec-07, Volume: 2, Issue:23

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Crown Ethers; Crystallography, X-Ray; Glycine; Hydrogen Bonding; Isoleucine; Isomerism; Methionine; Models, Chemical; Molecular Conformation; Molecular Structure; Thermodynamics; Tyrosine

2004
Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Dec-01, Volume: 15, Issue:23

    Topics: Administration, Oral; Animals; Anticoagulants; Biological Availability; Crystallography, X-Ray; Drug Design; Factor VIIa; Glycine; Humans; Molecular Structure; Rats; Serine Proteinase Inhibitors; Thromboplastin

2005
The conformers of phenylglycine.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2006, Mar-08, Volume: 12, Issue:9

    Topics: Glycine; Hydrogen Bonding; Laser Therapy; Microwaves; Molecular Conformation; Spectrum Analysis

2006
Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme.
    The Journal of biological chemistry, 2006, Mar-03, Volume: 281, Issue:9

    Topics: Acetobacter; Anti-Bacterial Agents; Binding Sites; Carboxylic Ester Hydrolases; Crystallography, X-Ray; Glycine; Lactams; Models, Molecular; Molecular Sequence Data; Mutation; Protein Structure, Quaternary; Protein Structure, Tertiary; Substrate Specificity

2006
Investigation and characterization of liquid two-phase systems for the separation of crystal mixtures by interfacial partitioning.
    Biotechnology and bioengineering, 2006, Mar-05, Volume: 93, Issue:4

    Topics: 1-Butanol; Adsorption; Alkanes; Ampicillin; Chemistry, Pharmaceutical; Crystallization; Flocculation; Glycine; Methanol; Pentanes; Water

2006
Metabolic engineering of the E. coli L-phenylalanine pathway for the production of D-phenylglycine (D-Phg).
    Metabolic engineering, 2006, Volume: 8, Issue:3

    Topics: Escherichia coli; Genetic Enhancement; Glucose; Glycine; Multienzyme Complexes; Protein Engineering; Recombinant Proteins

2006
(L)-Phenylglycine, but not necessarily other alpha2delta subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats.
    Pain, 2006, Volume: 125, Issue:1-2

    Topics: Analgesics; Animals; Brain; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Glycine; Hyperesthesia; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Treatment Outcome

2006
Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.
    Bioorganic & medicinal chemistry, 2007, Feb-01, Volume: 15, Issue:3

    Topics: Antiviral Agents; Binding Sites; Glycine; Hepacivirus; Humans; Models, Molecular; Protease Inhibitors; Protein Binding; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication

2007
Isolation and characterization of a benzoylformate decarboxylase and a NAD+/NADP+-dependent benzaldehyde dehydrogenase involved in D-phenylglycine metabolism in Pseudomonas stutzeri ST-201.
    Biochimica et biophysica acta, 2007, Volume: 1770, Issue:11

    Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Benzaldehyde Dehydrogenase (NADP+); Carboxy-Lyases; Escherichia coli; Glycine; Molecular Sequence Data; NAD; NADP; Pseudomonas stutzeri; Recombinant Proteins

2007
Production of D-phenylglycine-related amino acids by immobilized microbial cells.
    Biochimie, 1980, Volume: 62, Issue:5-6

    Topics: Acrylic Resins; Amidohydrolases; Amino Acids; Bacillus; Bacteria; Biochemistry; Catalysis; Cells, Immobilized; Glycine; Hydantoins; Hydrolysis; Models, Chemical; Substrate Specificity; Urea

1980
Solvent migration from the C- to the N-terminus of amino acid in photoionization of phenylglycine-water complex.
    The Journal of chemical physics, 2008, Jan-28, Volume: 128, Issue:4

    Topics: Amino Acids; Carbon; Cations; Decarboxylation; Free Radicals; Glycine; Models, Molecular; Nitrogen; Photochemistry; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Water

2008
Conformational study of jet-cooled L-phenylglycine.
    The Journal of chemical physics, 2008, May-14, Volume: 128, Issue:18

    Topics: Algorithms; Cold Temperature; Glycine; Helium; Hydrogen Bonding; Molecular Conformation; Photochemistry; Spectrum Analysis

2008
Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 330, Issue:3

    Topics: Algorithms; Animals; Binding Sites; Blotting, Western; Calcium Channel Blockers; Chlorocebus aethiops; COS Cells; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Felodipine; Glycine; Mutagenesis; Mutation; Transfection

2009
Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Design; Glycine; Humans; Ion Channel Gating; Mutation; Protein Folding; Small Molecule Libraries; Structure-Activity Relationship; Thiazoles

2010
Predominant (S)-enantioselective inclusion of aryl methyl sulfoxides by (S)-isoleucyl-(S)-phenylglycines.
    The Journal of organic chemistry, 2010, Feb-05, Volume: 75, Issue:3

    Topics: Glycine; Hydrogen Bonding; Isoleucine; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Sulfoxides

2010
Synthesis of new imidazolidin-2,4-dione and 2-thioxoimidazolidin-4-ones via C-phenylglycine derivatives.
    Molecules (Basel, Switzerland), 2009, Dec-30, Volume: 15, Issue:1

    Topics: Glycine; Imidazolidines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thiohydantoins

2009
A straightforward three-component synthesis of alpha-amino esters containing a phenylalanine or a phenylglycine scaffold.
    The Journal of organic chemistry, 2010, Apr-16, Volume: 75, Issue:8

    Topics: Esters; Glycine; Indicators and Reagents; Phenylalanine

2010
Evidence of D-phenylglycine as delivering tool for improving L-dopa absorption.
    Journal of biomedical science, 2010, Sep-06, Volume: 17

    Topics: Animals; Biological Availability; Chromatography, High Pressure Liquid; Dopamine; Drug Carriers; Glycine; Humans; Intestinal Absorption; Levodopa; Microdialysis; Microvilli; Parkinson Disease; Peptide Transporter 1; Rats; Rats, Wistar; Rotarod Performance Test; Symporters; Transport Vesicles

2010
Chiral recognition of α-amino acids by an optically active (2S,5S,8S,11S)-2,5,8,11-tetraethyl cyclen cobalt(III) complex.
    Inorganic chemistry, 2011, Jan-03, Volume: 50, Issue:1

    Topics: Cobalt; Coordination Complexes; Crystallography, X-Ray; Glycine; Heterocyclic Compounds; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Stereoisomerism

2011
Identification and functional characterization of phenylglycine biosynthetic genes involved in pristinamycin biosynthesis in Streptomyces pristinaespiralis.
    Journal of biotechnology, 2011, Aug-20, Volume: 155, Issue:1

    Topics: Bacterial Proteins; Base Sequence; Computer Simulation; Genes, Bacterial; Glycine; Metabolic Networks and Pathways; Molecular Sequence Data; Mutagenesis, Insertional; Pristinamycin; Streptomyces

2011
Immobilization of chitosan in sol-gel phases for chiral open-tubular capillary electrochromatography.
    Analytica chimica acta, 2012, Mar-09, Volume: 718

    Topics: Alanine; Capillary Electrochromatography; Catechin; Chitosan; Glycine; Hydrophobic and Hydrophilic Interactions; Phase Transition; Sensitivity and Specificity; Silanes; Stereoisomerism; Tryptophan

2012
Syntheses and highly enantioselective fluorescent recognition of α-aminocarboxylic acid anions using chiral oxacalix[2]arene[2]bisbinaphthes.
    Chirality, 2012, Volume: 24, Issue:8

    Topics: Alanine; Calixarenes; Carboxylic Acids; Chemistry Techniques, Synthetic; Crown Ethers; Fluorescent Dyes; Glycine; Models, Molecular; Molecular Conformation; Phenylalanine; Stereoisomerism; Substrate Specificity

2012
Two plate-based colorimetric assays for screening α-amino acid ester hydrolase with high synthesis/hydrolysis ratio.
    Enzyme and microbial technology, 2012, Jul-15, Volume: 51, Issue:2

    Topics: Acinetobacter; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactams; Carboxylic Ester Hydrolases; Catalytic Domain; Cefaclor; Colorimetry; DNA, Bacterial; Enzyme Assays; Glycine; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Engineering; Recombinant Proteins; Xanthomonas

2012
Stereoselectivity in the salt-cocrystal products formed by phenylglycinol or phenylglycine with their respective sodium or hydrochloride salts.
    Chirality, 2013, Volume: 25, Issue:1

    Topics: Calorimetry, Differential Scanning; Crystallization; Ethanolamines; Glycine; X-Ray Diffraction

2013
Functional annotation and three-dimensional structure of an incorrectly annotated dihydroorotase from cog3964 in the amidohydrolase superfamily.
    Biochemistry, 2013, Jan-08, Volume: 52, Issue:1

    Topics: Agrobacterium tumefaciens; Amidohydrolases; Catalytic Domain; Crystallography, X-Ray; Dihydroorotase; Glycine; Models, Molecular; Ochrobactrum anthropi; Organophosphorus Compounds; Protein Conformation; Substrate Specificity

2013
Enantioselective N-acetylation of 2-phenylglycine by an unusual N-acetyltransferase from Chryseobacterium sp.
    Biotechnology letters, 2013, Volume: 35, Issue:7

    Topics: Acetylation; Acetyltransferases; Biotransformation; Chryseobacterium; DNA, Bacterial; Glycine; Molecular Sequence Data; Sequence Analysis, DNA

2013
HPLC-DAD evidence of the oscillatory chiral conversion of phenylglycine.
    Journal of chromatographic science, 2014, Volume: 52, Issue:4

    Topics: Chromatography, High Pressure Liquid; Glycine; Stereoisomerism

2014
Molecular characterization of a novel N-acetyltransferase from Chryseobacterium sp.
    Applied and environmental microbiology, 2014, Volume: 80, Issue:5

    Topics: Acetyl Coenzyme A; Acetyltransferases; Chryseobacterium; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression; Glycine; Kinetics; Molecular Sequence Data; Phenylacetates; Phylogeny; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity

2014
Cloning, overexpression, and characterization of a high enantioselective nitrilase from Sphingomonas wittichii RW1 for asymmetric synthesis of (R)-phenylglycine.
    Applied biochemistry and biotechnology, 2014, Volume: 173, Issue:2

    Topics: Amino Acid Sequence; Aminohydrolases; Cloning, Molecular; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Metals; Molecular Sequence Data; Recombinant Proteins; Sequence Alignment; Sequence Analysis; Sphingomonas; Stereoisomerism; Substrate Specificity; Temperature

2014
Karyopherin-centric control of nuclear pores based on molecular occupancy and kinetic analysis of multivalent binding with FG nucleoporins.
    Biophysical journal, 2014, Apr-15, Volume: 106, Issue:8

    Topics: Animals; beta Karyopherins; Glycine; Humans; Kinetics; Models, Molecular; Nuclear Pore; Nuclear Pore Complex Proteins; Protein Binding; Protein Structure, Tertiary; Surface Plasmon Resonance; Xenopus laevis

2014
Heterologous pathway for the production of L-phenylglycine from glucose by E. coli.
    Journal of biotechnology, 2014, Sep-30, Volume: 186

    Topics: Actinomycetales; Bacterial Proteins; Escherichia coli; Glucose; Glycine; Metabolic Networks and Pathways; Phenylalanine; Recombinant Proteins; Streptomyces; Transaminases

2014
Conformers, infrared spectrum, UV-induced photochemistry, and near-IR-induced generation of two rare conformers of matrix-isolated phenylglycine.
    The Journal of chemical physics, 2014, Oct-21, Volume: 141, Issue:15

    Topics: Entropy; Glycine; Infrared Rays; Models, Molecular; Molecular Conformation; Photochemical Processes; Spectrophotometry, Infrared; Ultraviolet Rays; Xenon

2014
A novel D-mandelate dehydrogenase used in three-enzyme cascade reaction for highly efficient synthesis of non-natural chiral amino acids.
    Journal of biotechnology, 2015, Feb-10, Volume: 195

    Topics: Alcohol Oxidoreductases; Bioreactors; Fungal Proteins; Glycine; Lactobacillus; Mandelic Acids; Pseudomonas putida; Racemases and Epimerases; Stereoisomerism

2015
Conformational behavior of phenylglycines and hydroxyphenylglycines and non-planarity of phenyl rings.
    Indian journal of biochemistry & biophysics, 2014, Volume: 51, Issue:5

    Topics: Benzene; Computer Simulation; Glycine; Models, Chemical; Molecular Conformation; Molecular Dynamics Simulation; Quantum Theory; Water

2014
Involvement of the TetR-Type Regulator PaaR in the Regulation of Pristinamycin I Biosynthesis through an Effect on Precursor Supply in Streptomyces pristinaespiralis.
    Journal of bacteriology, 2015, Jun-15, Volume: 197, Issue:12

    Topics: Acetyl Coenzyme A; Bacterial Proteins; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Regulator; Glycine; Molecular Structure; Pristinamycin; Streptomyces; Transcription, Genetic

2015
Monoselective o-C-H Functionalizations of Mandelic Acid and α-Phenylglycine.
    Journal of the American Chemical Society, 2015, Aug-12, Volume: 137, Issue:31

    Topics: Alkenes; Carbon; Catalysis; Glycine; Halogenation; Hydrogen; Mandelic Acids; Palladium; Substrate Specificity

2015
Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with L-phenylglycine scaffold.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Glycine; HCT116 Cells; HeLa Cells; Hep G2 Cells; Histone Deacetylase Inhibitors; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Permeability; Structure-Activity Relationship; Time Factors; Tumor Burden; U937 Cells; Xenograft Model Antitumor Assays

2015
PXD101 analogs with L-phenylglycine-containing branched cap as histone deacetylase inhibitors.
    Chemical biology & drug design, 2016, Volume: 88, Issue:4

    Topics: Binding Sites; Cell Proliferation; Glycine; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Molecular Docking Simulation; Optical Imaging; Sulfonamides

2016
Pulse EPR Measurements of Intramolecular Distances in a TOPP-Labeled Transmembrane Peptide in Lipids.
    Biophysical journal, 2016, Dec-06, Volume: 111, Issue:11

    Topics: Amino Acid Sequence; Cell Membrane; Cyclic N-Oxides; Diketopiperazines; Electron Spin Resonance Spectroscopy; Glycine; Lipid Bilayers; Models, Molecular; Peptides; Protein Conformation, alpha-Helical; Spin Labels

2016
Phenylglycine analogs are inhibitors of the neutral amino acid transporters ASCT1 and ASCT2 and enhance NMDA receptor-mediated LTP in rat visual cortex slices.
    Neuropharmacology, 2017, Volume: 126

    Topics: Amino Acid Transport System ASC; Animals; Astrocytes; Glutamate Plasma Membrane Transport Proteins; Glycine; HEK293 Cells; Humans; Long-Term Potentiation; Minor Histocompatibility Antigens; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Visual Cortex

2017
Design, synthesis and collagenase inhibitory activity of some novel phenylglycine derivatives as metalloproteinase inhibitors.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt B

    Topics: Collagenases; Drug Design; Glycine; Inhibitory Concentration 50; Matrix Metalloproteinase Inhibitors; Molecular Docking Simulation; Sequence Analysis, Protein; Structural Homology, Protein

2018
Characterization of the phenylglycine aminotransferase PglE from Streptomyces pristinaespiralis.
    Journal of biotechnology, 2018, Jul-20, Volume: 278

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Glycine; Glyoxylates; Mandelic Acids; Metabolic Networks and Pathways; Streptomyces; Transaminases

2018
Design, synthesis, and evaluation of novel l-phenylglycine derivatives as potential PPARγ lead compounds.
    Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14

    Topics: alpha-Glucosidases; Dose-Response Relationship, Drug; Drug Design; Glycine; Glycoside Hydrolase Inhibitors; Hep G2 Cells; Humans; Hypoglycemic Agents; Molecular Structure; PPAR gamma; Structure-Activity Relationship

2018
Highly Enantioselective Extraction of Phenylglycine by a Chiral Macrocyclic Receptor Based on Supramolecular Interactions.
    Organic letters, 2020, 02-07, Volume: 22, Issue:3

    Topics: Chloroform; Crystallography, X-Ray; Glycine; Macrocyclic Compounds; Models, Molecular; Molecular Structure; Stereoisomerism

2020
Genetic engineering approaches for the fermentative production of phenylglycines.
    Applied microbiology and biotechnology, 2020, Volume: 104, Issue:8

    Topics: Anti-Bacterial Agents; Fermentation; Genes, Bacterial; Genetic Engineering; Glycine; Operon; Pseudomonas putida; Stereoisomerism; Streptomyces; Streptomyces lividans; Synthetic Biology

2020
High level and enantioselective production of L-phenylglycine from racemic mandelic acid by engineered Escherichia coli using response surface methodology.
    Enzyme and microbial technology, 2020, Volume: 136

    Topics: Bacterial Proteins; Biocatalysis; Escherichia coli; Glycine; Industrial Microbiology; Kinetics; Mandelic Acids; Plasmids; Stereoisomerism

2020
A Four-Step Enzymatic Cascade for Efficient Production of L-Phenylglycine from Biobased L-Phenylalanine.
    Chembiochem : a European journal of chemical biology, 2022, 04-20, Volume: 23, Issue:8

    Topics: Amino Acids; Escherichia coli; Glycine; Phenylalanine

2022
Rational identification of a high catalytic efficiency leucine dehydrogenase and process development for efficient synthesis of l-phenylglycine.
    Biotechnology journal, 2023, Volume: 18, Issue:5

    Topics: Amino Acids; Catalysis; Glycine; Leucine; Leucine Dehydrogenase; Substrate Specificity

2023