Compounds > 2-phenyl-4-oxohydroquinoline
Page last updated: 2024-09-04

2-phenyl-4-oxohydroquinoline and terfenadine

2-phenyl-4-oxohydroquinoline has been researched along with terfenadine in 1 studies

Compound Research Comparison

Studies
(2-phenyl-4-oxohydroquinoline)		Trials
(2-phenyl-4-oxohydroquinoline)		Recent Studies (post-2010)
(2-phenyl-4-oxohydroquinoline)		Studies
(terfenadine)		Trials
(terfenadine)		Recent Studies (post-2010) (terfenadine)
26081,751568346

Protein Interaction Comparison

ProteinTaxonomy2-phenyl-4-oxohydroquinoline (IC50)terfenadine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.93
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.231
Epidermal growth factor receptorHomo sapiens (human)3.566
Tyrosine-protein kinase FynHomo sapiens (human)6.123
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.928
ATP-dependent translocase ABCB1Homo sapiens (human)1.8167
Cytochrome P450 3A4Homo sapiens (human)0.32
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.9
D(2) dopamine receptorHomo sapiens (human)6.167
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)0.35
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)2.34
Alpha-2C adrenergic receptorHomo sapiens (human)3.748
DRattus norvegicus (Norway rat)0.1288
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.1288
Substance-K receptorHomo sapiens (human)2.677
D(1A) dopamine receptorHomo sapiens (human)2.673
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.1288
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.1288
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)2.34
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.928
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.1288
Alpha-1D adrenergic receptorHomo sapiens (human)2.34
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.255
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.231
Histamine H1 receptorCavia porcellus (domestic guinea pig)0.094
Alpha-1A adrenergic receptorHomo sapiens (human)2.34
Histamine H1 receptorHomo sapiens (human)0.0115
Alpha-1B adrenergic receptorHomo sapiens (human)2.34
D(3) dopamine receptorHomo sapiens (human)1.503
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.048
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)2.34
5-hydroxytryptamine receptor 6Homo sapiens (human)1.306
Cytochrome P450 2J2Homo sapiens (human)8.1
C-C chemokine receptor type 5Homo sapiens (human)1.103
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.93
Sodium-dependent dopamine transporter Homo sapiens (human)0.255
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2233
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.93
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.125
Sodium channel protein type 5 subunit alphaHomo sapiens (human)0.971

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, M; Ambachew, B; Antonova-Koch, Y; Burrows, J; Calla, J; Campo, B; Chaumeau, V; Chen, K; Cheung, AL; Conway, AJ; Eribez, K; Fidock, DA; Gagaring, K; Gamo, FJ; Ibanez, M; Jado, JC; Kyle, DE; Lincoln, C; Llinás, M; Lukens, AK; Luth, MR; Maher, SP; McNamara, CW; Meister, S; Nosten, F; Ottilie, S; Owen, E; Plouffe, D; Rouillier, M; Sakata-Kato, T; Serrano, FN; Siegel, D; Taggard, CM; Vanaerschot, M; Winzeler, EA; Wirth, DF; Zhong, Y; Zhou, Y1

Other Studies

1 other study(ies) available for 2-phenyl-4-oxohydroquinoline and terfenadine

ArticleYear
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.
    Science (New York, N.Y.), 2018, 12-07, Volume: 362, Issue:6419

    Topics: Antimalarials; Chemoprevention; Drug Discovery; Drug Evaluation, Preclinical; Humans; Malaria; Mitochondria; Plasmodium

2018