2-phenyl-4-oxohydroquinoline has been researched along with fosbretabulin in 2 studies
| Studies (2-phenyl-4-oxohydroquinoline) | Trials (2-phenyl-4-oxohydroquinoline) | Recent Studies (post-2010) (2-phenyl-4-oxohydroquinoline) | Studies (fosbretabulin) | Trials (fosbretabulin) | Recent Studies (post-2010) (fosbretabulin) |
|---|---|---|---|---|---|
| 26 | 0 | 8 | 497 | 0 | 320 |
| Protein | Taxonomy | 2-phenyl-4-oxohydroquinoline (IC50) | fosbretabulin (IC50) |
|---|---|---|---|
| Tubulin polymerization-promoting protein | Homo sapiens (human) | 1.016 | |
| Tubulin alpha-1A chain | Sus scrofa (pig) | 1.82 | |
| Tubulin beta chain | Sus scrofa (pig) | 1.9428 | |
| Tubulin beta-4A chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta chain | Homo sapiens (human) | 1.663 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 0.009 | |
| Tubulin alpha-3C chain | Homo sapiens (human) | 1.663 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 1.08 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 1.005 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 1.2 | |
| Tubulin alpha-1B chain | Homo sapiens (human) | 1.663 | |
| Tubulin alpha-4A chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-4B chain | Homo sapiens (human) | 1.663 | |
| Vesicular acetylcholine transporter | Tetronarce californica (Pacific electric ray) | 1.8 | |
| Tubulin beta-3 chain | Homo sapiens (human) | 1.5801 | |
| Tubulin beta-2A chain | Homo sapiens (human) | 1.663 | |
| Beta-tubulin | Leishmania donovani | 1.95 | |
| Tubulin beta-8 chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-2B chain | Bos taurus (cattle) | 1.4484 | |
| Tubulin alpha-3E chain | Homo sapiens (human) | 1.663 | |
| Tubulin alpha-1A chain | Homo sapiens (human) | 1.663 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 1.4928 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 1.4037 | |
| Tubulin alpha-1C chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-6 chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-2B chain | Homo sapiens (human) | 1.663 | |
| Tubulin beta-1 chain | Homo sapiens (human) | 1.6366 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, JJ; Hamel, E; Juang, JP; Kuo, SC; Lednicer, D; Lee, HZ; Lin, CM; Lin, YT; Paull, KD; Wu, TS | 1 |
| Hackl, T; Hamel, E; Lee, KH; Mauger, A; Wu, JH; Xia, P; Xia, Y; Yang, ZY | 1 |
2 other study(ies) available for 2-phenyl-4-oxohydroquinoline and fosbretabulin
| Article | Year |
|---|---|
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.
Topics: Animals; Antineoplastic Agents; Humans; Intestinal Neoplasms; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nasopharyngeal Neoplasms; Quinolines; Quinolones; Software; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1993 |
Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents.
Topics: Antineoplastic Agents; Biopolymers; Drug Screening Assays, Antitumor; Humans; Mitosis; Pyrroles; Quinolones; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured | 2001 |