Compounds > 2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-one
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2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-one and pyrilamine

2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-one has been researched along with pyrilamine in 2 studies

Compound Research Comparison

Studies
(2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-one)		Trials
(2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-one)		Recent Studies (post-2010)
(2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-one)		Studies
(pyrilamine)		Trials
(pyrilamine)		Recent Studies (post-2010) (pyrilamine)
7001,86026116

Protein Interaction Comparison

ProteinTaxonomy2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-one (IC50)pyrilamine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.13
Alpha-2A adrenergic receptorHomo sapiens (human)2.976
Cytochrome P450 2D6Homo sapiens (human)0.3
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.997
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.13
Histamine H1 receptorCavia porcellus (domestic guinea pig)0.0015
Histamine H1 receptorRattus norvegicus (Norway rat)0.0126
Sodium-dependent serotonin transporterHomo sapiens (human)0.047
Histamine H1 receptorHomo sapiens (human)0.0166
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.788
Sodium-dependent dopamine transporter Homo sapiens (human)0.879
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.1
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.558

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bolognese, A; Calignano, A; Diurno, MV; Giordano, F; Mazzoni, O; Piscopo, E1
Calignano, A; Diurno, MV; Mazzoni, O; Piscopo, E1

Other Studies

2 other study(ies) available for 2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-one and pyrilamine

ArticleYear
Synthesis and antihistaminic activity of some thiazolidin-4-ones.
    Journal of medicinal chemistry, 1992, Jul-24, Volume: 35, Issue:15

    Topics: Animals; Female; Guinea Pigs; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Structure-Activity Relationship; Thiazoles; X-Ray Diffraction

1992
Studies on heterocyclic compounds: 1,3-thiazolidin-4-one derivatives. V. Pharmacological activity of substituted 2-phenyl-3-(N,N-dimethylaminoprophyl)-1,3-thiazolidin-4-one .
    Bollettino della Societa italiana di biologia sperimentale, 1991, Volume: 67, Issue:12

    Topics: Animals; Female; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrilamine; Schiff Bases; Structure-Activity Relationship; Thiazoles; Thiazolidines

1991