Compounds > 2-phenyl-1,2-benzisothiazol-3-(2h)-one

Page last updated: 2024-09-05

2-phenyl-1,2-benzisothiazol-3-(2h)-one and telaprevir

2-phenyl-1,2-benzisothiazol-3-(2h)-one has been researched along with telaprevir in 1 studies

Compound Research Comparison

Studies (2-phenyl-1,2-benzisothiazol-3-(2h)-one)	Trials (2-phenyl-1,2-benzisothiazol-3-(2h)-one)	Recent Studies (post-2010) (2-phenyl-1,2-benzisothiazol-3-(2h)-one)	Studies (telaprevir)	Trials (telaprevir)	Recent Studies (post-2010) (telaprevir)
23	0	11	985	136	835

Protein Interaction Comparison

Protein	Taxonomy	2-phenyl-1,2-benzisothiazol-3-(2h)-one (IC50)	telaprevir (IC50)
NS3 protease			0.9757
Cathepsin L2	Homo sapiens (human)		1.35
Prothrombin	Homo sapiens (human)		1
Plasminogen	Homo sapiens (human)		8.7
Procathepsin L	Homo sapiens (human)		3.5
Cathepsin B	Homo sapiens (human)		2.3033
Neutrophil elastase	Homo sapiens (human)		5.56
Chymase	Homo sapiens (human)		0.026
Cathepsin S	Homo sapiens (human)		0.3
Cathepsin K	Homo sapiens (human)		0.63
Chymotrypsin-like elastase family member 1	Homo sapiens (human)		0.03

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (100.00)	2.80

Authors

Authors	Studies
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW	1

Other Studies

1 other study(ies) available for 2-phenyl-1,2-benzisothiazol-3-(2h)-one and telaprevir

Article	Year
Perspectives on SARS-CoV-2 Main Protease Inhibitors. Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23 Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors	2021