Compounds > 2-phenyl-1,2-benzisothiazol-3-(2h)-one
Page last updated: 2024-09-05

2-phenyl-1,2-benzisothiazol-3-(2h)-one and 6-fluoro-2-phenyl-1,2-benzothiazol-3-one

2-phenyl-1,2-benzisothiazol-3-(2h)-one has been researched along with 6-fluoro-2-phenyl-1,2-benzothiazol-3-one in 1 studies

Compound Research Comparison

Studies
(2-phenyl-1,2-benzisothiazol-3-(2h)-one)		Trials
(2-phenyl-1,2-benzisothiazol-3-(2h)-one)		Recent Studies (post-2010)
(2-phenyl-1,2-benzisothiazol-3-(2h)-one)		Studies
(6-fluoro-2-phenyl-1,2-benzothiazol-3-one)		Trials
(6-fluoro-2-phenyl-1,2-benzothiazol-3-one)		Recent Studies (post-2010) (6-fluoro-2-phenyl-1,2-benzothiazol-3-one)
23011501

Protein Interaction Comparison

ProteinTaxonomy2-phenyl-1,2-benzisothiazol-3-(2h)-one (IC50)6-fluoro-2-phenyl-1,2-benzothiazol-3-one (IC50)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei10.6267
hexokinaseTrypanosoma brucei brucei TREU9272.31
caspase recruitment domain family, member 15Homo sapiens (human)5.428
glucose-6-phosphate 1-dehydrogenase isoform bHomo sapiens (human)11.8
receptor-interacting serine/threonine-protein kinase 2 isoform 1Homo sapiens (human)5.428
rac GTPase-activating protein 1 isoform aHomo sapiens (human)36.43
Neutrophil elastaseHomo sapiens (human)2.31
Mannose-6-phosphate isomeraseHomo sapiens (human)1.3
Phosphoethanolamine/phosphocholine phosphataseHomo sapiens (human)0.79

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bravo, Y; Cosford, ND; Dahl, R; Dhanya, RP; Farquharson, C; Ganji, SR; Kiffer-Moreira, T; Lee, PS; Millán, JL; Sergienko, E; Smith, LH; Teriete, P1

Other Studies

1 other study(ies) available for 2-phenyl-1,2-benzisothiazol-3-(2h)-one and 6-fluoro-2-phenyl-1,2-benzothiazol-3-one

ArticleYear
Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.
    Bioorganic & medicinal chemistry letters, 2014, Sep-01, Volume: 24, Issue:17

    Topics: Animals; Benzamides; Benzothiazoles; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Hepatocytes; High-Throughput Screening Assays; Humans; Hydrogen-Ion Concentration; Mice; Molecular Structure; Phosphoric Monoester Hydrolases; Small Molecule Libraries; Structure-Activity Relationship

2014