Page last updated: 2024-09-03

2-oxohistidine and histidine

2-oxohistidine has been researched along with histidine in 16 studies

Compound Research Comparison

Studies
(2-oxohistidine)
Trials
(2-oxohistidine)
Recent Studies (post-2010)
(2-oxohistidine)
Studies
(histidine)
Trials
(histidine)
Recent Studies (post-2010) (histidine)
160322,0461144,371

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (50.00)18.2507
2000's5 (31.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawakishi, S; Uchida, K2
Levine, RL; Lewisch, SA2
Butler, A; Meister Winter, GE1
Floyd, RA; Kwon, OJ; Lee, SM; Park, JW1
Chen, K; Frei, B; Retsky, KL; Zeind, J1
Abel, JM; Ghanevati, M; Jewett, SL; Marach, JA; Rocklin, AM1
Schöneich, C2
Schöneich, C; Williams, TD1
Biesiada, H; Hovorka, SW; Hühmer, A; Schöneich, C; Williams, TD1
John, JPP; Lubec, G; Pollak, A1
Hutton, CA; Lam, AK; O'Hair, RA1
Huang, CF; Liu, YH; Tai, HC1
Chen, CS; Lin, JM; Lin, Y; Liu, YH; Tai, HC; Tsai, YT1

Reviews

1 review(s) available for 2-oxohistidine and histidine

ArticleYear
Protein modification in aging: an update.
    Experimental gerontology, 2006, Volume: 41, Issue:9

    Topics: Aging; Histidine; Humans; Lamin Type A; Neurodegenerative Diseases; Nuclear Proteins; Oxidation-Reduction; Progeria; Protein Precursors; Protein Processing, Post-Translational; Pyruvaldehyde; Transglutaminases; Tyrosine

2006

Other Studies

15 other study(ies) available for 2-oxohistidine and histidine

ArticleYear
Identification of oxidized histidine generated at the active site of Cu,Zn-superoxide dismutase exposed to H2O2. Selective generation of 2-oxo-histidine at the histidine 118.
    The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Erythrocytes; Histidine; Hydrogen Peroxide; Kinetics; Macromolecular Substances; Peptide Fragments; Peptide Mapping; Superoxide Dismutase; Time Factors

1994
2-Oxo-histidine as a novel biological marker for oxidatively modified proteins.
    FEBS letters, 1993, Oct-18, Volume: 332, Issue:3

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Electrochemistry; Histidine; Indicators and Reagents; Oxidation-Reduction; Proteins; Serum Albumin, Bovine

1993
Determination of 2-oxohistidine by amino acid analysis.
    Analytical biochemistry, 1995, Nov-01, Volume: 231, Issue:2

    Topics: Amino Acids; Biomarkers; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glutamate-Ammonia Ligase; Histidine; Oxidation-Reduction; Oxidative Stress; Sensitivity and Specificity

1995
Inactivation of vanadium bromoperoxidase: formation of 2-oxohistidine.
    Biochemistry, 1996, Sep-10, Volume: 35, Issue:36

    Topics: Bromates; Bromides; Chromatography, High Pressure Liquid; Electrochemistry; Eukaryota; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Oxidation-Reduction; Peroxidases; Vanadium Compounds

1996
Thiol-dependent metal-catalyzed oxidation of copper, zinc superoxide dismutase.
    Biochimica et biophysica acta, 1998, Sep-08, Volume: 1387, Issue:1-2

    Topics: Chelating Agents; Copper; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Free Radical Scavengers; Histidine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Metals; Oxidation-Reduction; Oxidative Stress; Oxygen; Spin Labels; Sulfhydryl Compounds; Superoxide Dismutase

1998
Inhibition of copper-induced LDL oxidation by vitamin C is associated with decreased copper-binding to LDL and 2-oxo-histidine formation.
    Free radical biology & medicine, 1999, Volume: 26, Issue:1-2

    Topics: Antioxidants; Arteriosclerosis; Ascorbic Acid; Binding Sites; Copper; Dehydroascorbic Acid; Histidine; Humans; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Protein Binding

1999
Determination of 2-oxohistidine by amino acid analysis.
    Methods in enzymology, 1999, Volume: 300

    Topics: Amino Acids; Chromatography, Ion Exchange; Dithiothreitol; Histidine; Hydrolysis

1999
A new look at a time-worn system: oxidation of CuZn-SOD by H2O2.
    Free radical biology & medicine, 1999, Volume: 26, Issue:7-8

    Topics: Animals; Biomarkers; Cattle; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Liver; Models, Chemical; Oxidation-Reduction; Spectrophotometry; Superoxide Dismutase

1999
Mechanisms of metal-catalyzed oxidation of histidine to 2-oxo-histidine in peptides and proteins.
    Journal of pharmaceutical and biomedical analysis, 2000, Volume: 21, Issue:6

    Topics: Catalysis; Histidine; Humans; Metals; Oxidation-Reduction; Peptides; Proteins

2000
Cu(II)-catalyzed oxidation of beta-amyloid peptide targets His13 and His14 over His6: Detection of 2-Oxo-histidine by HPLC-MS/MS.
    Chemical research in toxicology, 2002, Volume: 15, Issue:5

    Topics: Amyloid beta-Peptides; Chromatography, High Pressure Liquid; Copper; Histidine; Mass Spectrometry; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization

2002
High sensitivity of Zn2+ insulin to metal-catalyzed oxidation: detection of 2-oxo-histidine by tandem mass spectrometry.
    Pharmaceutical research, 2002, Volume: 19, Issue:4

    Topics: Catalysis; Chromatography, High Pressure Liquid; Histidine; Humans; Insulin; Metals, Heavy; Oxidation-Reduction; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Zinc

2002
Complete sequencing and oxidative modification of manganese superoxide dismutase in medulloblastoma cells.
    Electrophoresis, 2009, Volume: 30, Issue:17

    Topics: Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; Histidine; Humans; Medulloblastoma; Oxidation-Reduction; Peptide Fragments; Protein Processing, Post-Translational; Proteomics; Sequence Analysis, Protein; Superoxide Dismutase; Tryptophan

2009
Role of 2-oxo and 2-thioxo modifications on the fragmentation reactions of the histidine radical cation.
    Rapid communications in mass spectrometry : RCM, 2011, Jan-30, Volume: 25, Issue:2

    Topics: Carbon Dioxide; Cations; Free Radicals; Histidine; Oxygen; Spectrometry, Mass, Electrospray Ionization; Sulfur; Sulfur Compounds

2011
Synthesis of peptides containing 2-oxohistidine residues and their characterization by liquid chromatography-tandem mass spectrometry.
    Journal of peptide science : an official publication of the European Peptide Society, 2015, Volume: 21, Issue:2

    Topics: Chromatography, High Pressure Liquid; Histidine; Peptides; Tandem Mass Spectrometry

2015
Identification of 2-oxohistidine Interacting Proteins Using E. coli Proteome Chips.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:12

    Topics: Amino Acid Motifs; Binding Sites; Escherichia coli Proteins; High-Throughput Screening Assays; Histidine; Humans; Models, Molecular; Oxidation-Reduction; Protein Array Analysis; Protein Binding; Protein Interaction Maps; Protein Structure, Secondary; Proteome; S100 Proteins

2016