2-oxindole has been researched along with su 11248 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, SY; Li, S; Liu, HY; Liu, ML; Lv, K; Wang, LL; Zheng, ZB; Zhou, XB | 1 |
| Gong, P; Lv, Y; Wang, S; Zhang, G; Zhang, N; Zhao, Y | 1 |
| Fan, C; Gong, X; Yang, Y; Zhang, L; Zhao, S; Zheng, Q; Zhou, H | 1 |
| Chen, G; Fu, L; Li, X; Liang, G; Liu, Z; Wang, Z; Weng, Q; Yu, P; Zhang, H | 1 |
| Chai, CL; Ho, HK; Ngai, MH; So, CL; Sullivan, MB | 1 |
| Agalou, A; Argyros, O; Asvos, X; Beis, D; Davos, CH; Fokas, D; Karampelas, T; Papakyriakou, A; Tamvakopoulos, C; Varela, A | 1 |
| Ghodsi, R; Yousefian, M | 1 |
| Aboul-Fadl, T; El-Sayed, WM; Hassan, MA; Qayed, WS; Rogério A Silva, J | 1 |
1 review(s) available for 2-oxindole and su 11248
| Article | Year |
|---|---|
Structure-activity relationship studies of indolin-2-one derivatives as vascular endothelial growth factor receptor inhibitors and anticancer agents.
Topics: Angiogenesis Inhibitors; Animals; Humans; Indoles; Molecular Structure; Neoplasms; Neovascularization, Pathologic; Protein Kinase Inhibitors; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Structure-Activity Relationship; Sunitinib | 2020 |
7 other study(ies) available for 2-oxindole and su 11248
| Article | Year |
|---|---|
Synthesis and antitumor activity of 5-[1-(3-(dimethylamino)propyl)-5-halogenated-2-oxoindolin-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamides.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Design; Halogens; Humans; Indoles; Inhibitory Concentration 50; Molecular Structure; Pyrroles; Sunitinib | 2011 |
Design, synthesis and biological evaluation of novel 4-thiazolidinones containing indolin-2-one moiety as potential antitumor agent.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Fibroblasts; Humans; Indoles; Inhibitory Concentration 50; Liver Neoplasms; Lung Neoplasms; Pyrroles; Sunitinib; Thiazolidines | 2011 |
Synthesis and in vivo SAR study of indolin-2-one-based multi-targeted inhibitors as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Indoles; Mice; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Structure-Activity Relationship; Sunitinib | 2014 |
Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Design; G1 Phase Cell Cycle Checkpoints; Humans; Indoles; Molecular Docking Simulation; Oxindoles; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib | 2014 |
Photoinduced Isomerization and Hepatoxicities of Semaxanib, Sunitinib and Related 3-Substituted Indolin-2-ones.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Indoles; Liver Neoplasms; Molecular Structure; Photochemical Processes; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Stereoisomerism; Structure-Activity Relationship; Sunitinib | 2016 |
Targeting of the breast cancer microenvironment with a potent and linkable oxindole based antiangiogenic small molecule.
Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Mice; Mice, Inbred C57BL; Mice, SCID; Neoplasms, Experimental; Oxindoles; Pyrroles; Sunitinib; Tumor Burden; Tumor Microenvironment; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2017 |
Novel Azine Linked Hybrids of 2-Indolinone and Thiazolodinone Scaffolds as CDK2 Inhibitors with Potential Anticancer Activity: In Silico Design, Synthesis, Biological, Molecular Dynamics and Binding Free Energy Studies.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Oxindoles; Structure-Activity Relationship; Sunitinib | 2022 |