2-oxindole has been researched along with pyrroles in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 28 (90.32) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Adams, AL; Adams, WR; Berrodin, TJ; Cohen, J; Fensome, A; Hudak, VA; Huselton, C; Illenberger, A; Kern, JC; Marella, MA; McComas, CC; Melenski, EG; Mugford, CA; Slayden, OD; Winneker, RC; Wrobel, JE; Yudt, M; Zhang, P; Zhang, Z; Zhu, Y | 1 |
| Ashenhurst, JA; Movassaghi, M; Schmidt, MA | 1 |
| Chang, CN; Chen, CH; Chen, GS; Chen, YC; Chern, JW; Chou, NT; Chou, SH; Hseu, TH; Hsu, HC; Hu, TL; Huang, CH; Hwang, CS; Khanwelkar, RR; Ko, CH; Lee, O; Lin, HC; Lin, MW; Liu, CP; Shih, YC; Tsai, YJ; Tseng, HW; Tu, CM; Wang, HC; Wang, LM; Yu, CW | 1 |
| Chin, HF; De La Cruz, EM; Islam, K; Kapoor, TM; Olivares, AO; Saunders, LP | 1 |
| Cheng, JP; Li, X; Luo, S | 1 |
| Roth, GP; Singh, A | 1 |
| Fan, SY; Li, S; Liu, HY; Liu, ML; Lv, K; Wang, LL; Zheng, ZB; Zhou, XB | 1 |
| Gong, P; Lv, Y; Wang, S; Zhang, G; Zhang, N; Zhao, Y | 1 |
| Ai, Y; Song, FJ; Sun, PH; Wang, ST | 1 |
| Snell, RH; Willis, MC; Woodward, RL | 1 |
| Fu, DX; Jin, YZ; Li, ZC; Liu, QH; Ma, N; Xiao, L; Zhang, RH | 1 |
| Chen, PH; Gong, LZ; Guo, C; Huang, JZ; Luo, SW; Song, J | 1 |
| Chen, CX; Lu, RJ; Wang, JJ; Wei, WT; Yan, M; Zhang, XJ | 1 |
| Sun, J; Wu, L; Yan, CG | 1 |
| Basiri, A; Bing, CS; Kia, Y; Kumar, RS; Murugaiyah, V; Osman, H; Perumal, S; Wahab, HA | 1 |
| Basiri, A; Kia, Y; Kumar, RS; Murugaiyah, V; Osman, H; Perumal, S; Razak, IA | 1 |
| Liu, R; Zhang, J | 1 |
| Chen, W; Jiang, Z; Tan, CH; Yan, L; Yang, W | 1 |
| Kouznetsov, VV; Puerto Galvis, CE | 1 |
| Fan, C; Gong, X; Yang, Y; Zhang, L; Zhao, S; Zheng, Q; Zhou, H | 1 |
| Cui, BD; Wu, ZJ; Xu, XY; You, Y; Yuan, WC; Zhang, XM; Zhao, JQ; Zuo, J | 1 |
| Chen, G; Fu, L; Li, X; Liang, G; Liu, Z; Wang, Z; Weng, Q; Yu, P; Zhang, H | 1 |
| Bisai, A; Chaudhuri, S; Ghosh, S | 1 |
| Cui, BD; Xu, XY; You, Y; Yuan, WC; Zhang, XM; Zhao, JQ; Zhou, MQ; Zuo, J | 1 |
| Wang, ZH; Wu, ZJ; Xu, XY; You, Y; Yuan, WC; Zhang, XM | 1 |
| Chai, CL; Ho, HK; Ngai, MH; So, CL; Sullivan, MB | 1 |
| Chen, X; He, Z; Tang, T; Yang, C | 1 |
| Agalou, A; Argyros, O; Asvos, X; Beis, D; Davos, CH; Fokas, D; Karampelas, T; Papakyriakou, A; Tamvakopoulos, C; Varela, A | 1 |
| Babu, KN; Bisai, A; Kinthada, LK; Medisetty, SR; Parida, A | 1 |
| Chen, Y; Cui, B; Han, W; Qin, L; Shan, J; Wan, N; Wang, Y; Yuan, C | 1 |
| Amrutha Krishnan, AV; Bharitkar, YP; Hazra, A; Mandal, R; Natarajan, R; Ravichandiran, V; Samanta, J; Singh, M | 1 |
31 other study(ies) available for 2-oxindole and pyrroles
| Article | Year |
|---|---|
Design, synthesis, and SAR of new pyrrole-oxindole progesterone receptor modulators leading to 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348).
Topics: Administration, Oral; Alkaline Phosphatase; Animals; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Indoles; Macaca fascicularis; Macaca mulatta; Molecular Structure; Ovulation; Oxindoles; Pyrroles; Rats; Receptors, Progesterone; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2008 |
Stereoselective oxidative rearrangement of 2-aryl tryptamine derivatives.
Topics: Alkaloids; Indoles; Oxidation-Reduction; Oxindoles; Pyrroles; Stereoisomerism; Substrate Specificity; Tryptamines | 2008 |
Synthesis and structure-activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors.
Topics: Animals; Aurora Kinases; Binding Sites; Cell Line, Tumor; Computer Simulation; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Indoles; Leukemia, Myeloid; Mice; Oxindoles; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrroles; Receptors, Platelet-Derived Growth Factor; Structure-Activity Relationship; Transplantation, Heterologous; Urea | 2010 |
A myosin V inhibitor based on privileged chemical scaffolds.
Topics: Animals; Enzyme Inhibitors; Humans; Indoles; Kinetics; Mice; Myosin Type V; Oxindoles; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2010 |
Asymmetric conjugate addition of oxindoles to 2-chloroacrylonitrile: a highly effective organocatalytic strategy for simultaneous construction of 1,3-nonadjacent stereocenters leading to chiral pyrroloindolines.
Topics: Acrylonitrile; Catalysis; Combinatorial Chemistry Techniques; Hydrocarbons, Chlorinated; Indole Alkaloids; Indoles; Oxindoles; Pyrroles; Stereoisomerism; Thiourea | 2010 |
A [3+2] dipolar cycloaddition route to 3-hydroxy-3-alkyl oxindoles: an approach to pyrrolidinoindoline alkaloids.
Topics: Alkaloids; Alkylation; Amino Alcohols; Cyclization; Hydroxylation; Indoles; Molecular Structure; Oxindoles; Pyrroles | 2011 |
Synthesis and antitumor activity of 5-[1-(3-(dimethylamino)propyl)-5-halogenated-2-oxoindolin-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamides.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Design; Halogens; Humans; Indoles; Inhibitory Concentration 50; Molecular Structure; Pyrroles; Sunitinib | 2011 |
Design, synthesis and biological evaluation of novel 4-thiazolidinones containing indolin-2-one moiety as potential antitumor agent.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Fibroblasts; Humans; Indoles; Inhibitory Concentration 50; Liver Neoplasms; Lung Neoplasms; Pyrroles; Sunitinib; Thiazolidines | 2011 |
Combined 3D-QSAR modeling and molecular docking studies on pyrrole-indolin-2-ones as Aurora A kinase inhibitors.
Topics: Aurora Kinase A; Binding Sites; Indoles; Molecular Docking Simulation; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrroles; Quantitative Structure-Activity Relationship | 2011 |
Catalytic enantioselective total synthesis of hodgkinsine B.
Topics: Catalysis; Indoles; Oxindoles; Palladium; Pyrroles; Stereoisomerism | 2011 |
Synthesis and biological evaluation of 3-substituted-indolin-2-one derivatives containing chloropyrrole moieties.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chlorine; Drug Screening Assays, Antitumor; Humans; Indoles; Intercellular Signaling Peptides and Proteins; Mice; Molecular Structure; Pyrroles; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Core-structure-oriented asymmetric organocatalytic substitution of 3-hydroxyoxindoles: application in the enantioselective total synthesis of (+)-folicanthine.
Topics: Carbamates; Catalysis; Indoles; Oxindoles; Phosphoric Acids; Pyrroles; Stereoisomerism | 2012 |
Enantioselective synthesis of 3,3'-dihydropyrryl-spirooxindoles via an organocatalytic three-component reaction.
Topics: Biological Products; Catalysis; Hydroxylation; Indoles; Models, Molecular; Molecular Structure; Oxindoles; Pyrroles; Spiro Compounds; Stereoisomerism | 2012 |
Facile synthesis of spiro[indoline-3,3'-pyrrolo[1,2-a]quinolines] and spiro[indoline-3,1'-pyrrolo[2,1-a]isoquinolines] via 1,3-dipolar cycloaddition reactions of heteroaromatic ammonium salts with 3-phenacylideneoxindoles.
Topics: Cycloaddition Reaction; Indoles; Molecular Structure; Oxindoles; Pyrroles; Quaternary Ammonium Compounds; Quinolines; Salts; Spiro Compounds; Stereoisomerism | 2012 |
Synthesis and discovery of novel piperidone-grafted mono- and bis-spirooxindole-hexahydropyrrolizines as potent cholinesterase inhibitors.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Indoles; Inhibitory Concentration 50; Models, Molecular; Oxindoles; Piperidones; Pyrroles; Spiro Compounds | 2013 |
A facile chemo-, regio- and stereoselective synthesis and cholinesterase inhibitory activity of spirooxindole-pyrrolizine-piperidine hybrids.
Topics: Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Cyclization; Dose-Response Relationship, Drug; Indoles; Models, Molecular; Molecular Structure; Oxindoles; Piperidines; Pyrroles; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2013 |
Organocatalytic Michael addition of indoles to isatylidene-3-acetaldehydes: application to the formal total synthesis of (-)-chimonanthine.
Topics: Acetaldehyde; Catalysis; Indoles; Molecular Structure; Oxindoles; Piperazines; Pyrroles; Pyrrolidinones; Stereoisomerism | 2013 |
Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation: direct access to pyrroloindolines and furoindolines.
Topics: Alkylation; Bridged Bicyclo Compounds; Catalysis; Guanidine; Hydrocarbons, Brominated; Indoles; Molecular Structure; Organometallic Compounds; Oxindoles; Phase Transition; Pyrroles; Stereoisomerism | 2013 |
Regio- and stereoselective synthesis of spirooxindole 1'-nitro pyrrolizidines with five concurrent stereocenters under aqueous medium and their bioprospection using the zebrafish (Danio rerio) embryo model.
Topics: Animals; Blood-Brain Barrier; Chemistry Techniques, Synthetic; Computer Simulation; Embryo, Nonmammalian; Indoles; Oxindoles; Phenotype; Pyrroles; Stereoisomerism; Substrate Specificity; Water; Zebrafish | 2013 |
Synthesis and in vivo SAR study of indolin-2-one-based multi-targeted inhibitors as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Indoles; Mice; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Structure-Activity Relationship; Sunitinib | 2014 |
3-Pyrrolyl-oxindoles as efficient nucleophiles for organocatalytic asymmetric synthesis of structurally diverse 3,3'-disubstituted oxindole derivatives.
Topics: Alkenes; Catalysis; Indoles; Nitro Compounds; Oxindoles; Pyrroles | 2015 |
Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Design; G1 Phase Cell Cycle Checkpoints; Humans; Indoles; Molecular Docking Simulation; Oxindoles; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib | 2014 |
Oxidative dimerization of 2-oxindoles promoted by KO(t)Bu-I₂: total synthesis of (±)-folicanthine.
Topics: Catalysis; Dimerization; Hydrocarbons, Iodinated; Indole Alkaloids; Indoles; Molecular Structure; Oxidative Coupling; Oxindoles; Pyrroles; Stereoisomerism | 2015 |
Organocatalytic Asymmetric Michael/Friedel-Crafts Cascade Reaction of 3-Pyrrolyl-oxindoles and α,β-Unsaturated Aldehydes for the Construction of Chiral Spiro[5,6-dihydropyrido[1,2-a]pyrrole-3,3'-oxindoles].
Topics: Aldehydes; Catalysis; Indoles; Molecular Structure; Oxindoles; Pyrroles; Spiro Compounds; Stereoisomerism | 2015 |
Enantioselective Synthesis of 3,3-Disubstituted Oxindoles Bearing Two Different Heteroatoms at the C3 Position by Organocatalyzed Sulfenylation and Selenenylation of 3-Pyrrolyl-oxindoles.
Topics: Catalysis; Cinchona Alkaloids; Heterocyclic Compounds; Indoles; Molecular Structure; Oxindoles; Pyrroles; Selenium Compounds; Stereoisomerism; Sulfhydryl Compounds | 2015 |
Photoinduced Isomerization and Hepatoxicities of Semaxanib, Sunitinib and Related 3-Substituted Indolin-2-ones.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Indoles; Liver Neoplasms; Molecular Structure; Photochemical Processes; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Stereoisomerism; Structure-Activity Relationship; Sunitinib | 2016 |
Annulation Reaction of 3-Acylmethylidene Oxindoles with Huisgen Zwitterions and Its Applications in the Syntheses of Pyrrolo[4,3,2-de]quinolinones and Marine Alkaloids Ammosamides.
Topics: Alkaloids; Amides; Biological Products; Heterocyclic Compounds, 3-Ring; Indoles; Marine Biology; Molecular Structure; Oxindoles; Pyrroles; Quinolines; Quinolones; Structure-Activity Relationship | 2016 |
Targeting of the breast cancer microenvironment with a potent and linkable oxindole based antiangiogenic small molecule.
Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Mice; Mice, Inbred C57BL; Mice, SCID; Neoplasms, Experimental; Oxindoles; Pyrroles; Sunitinib; Tumor Burden; Tumor Microenvironment; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2017 |
FeCl
Topics: Allyl Compounds; Catalysis; Chlorides; Ferric Compounds; Indoles; Molecular Structure; Oxindoles; Pyrroles; Stereoisomerism | 2017 |
An enantioselective synthesis of spiro-oxindole-based 3,4-dihydropyrroles via a Michael/cyclization cascade of 3-aminooxindoles with 2-enoylpyridines.
Topics: Cyclization; Indoles; Molecular Structure; Oxindoles; Pyridines; Pyrroles; Spiro Compounds; Stereoisomerism | 2017 |
Azomethine ylide cycloaddition: a versatile tool for preparing novel pyrrolizidino-spiro-oxindolo hybrids of the doubly conjugated alkamide piperine.
Topics: Alkaloids; Azo Compounds; Benzodioxoles; Cycloaddition Reaction; Models, Molecular; Molecular Conformation; Oxindoles; Piperidines; Polyunsaturated Alkamides; Pyrroles; Spiro Compounds; Stereoisomerism; Thiosemicarbazones | 2020 |