Page last updated: 2024-09-03

2-naphthoylglycine and sorbinil

2-naphthoylglycine has been researched along with sorbinil in 2 studies

Compound Research Comparison

Studies
(2-naphthoylglycine)
Trials
(2-naphthoylglycine)
Recent Studies (post-2010)
(2-naphthoylglycine)
Studies
(sorbinil)
Trials
(sorbinil)
Recent Studies (post-2010) (sorbinil)
5015004443

Protein Interaction Comparison

ProteinTaxonomy2-naphthoylglycine (IC50)sorbinil (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)5.05
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.8698
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.5
Aldo-keto reductase family 1 member A1Homo sapiens (human)5.1333
Aldo-keto reductase family 1 member B1Homo sapiens (human)1.3166
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)3.04
Aldo-keto reductase family 1 member B1Bos taurus (cattle)1.7292
Aldo-keto reductase family 1 member A1Sus scrofa (pig)2.95
Aldo-keto reductase family 1 member A1Rattus norvegicus (Norway rat)0.8845
Aldo-keto reductase family 1 member B1Sus scrofa (pig)1.1
Mu-type opioid receptorCavia porcellus (domestic guinea pig)1.1

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, RA; DeRuiter, J; Mayfield, CA; Wandrekar, VG1
DeRuiter, J; Mayfield, CA; Swearingen, BE; Wandrekar, V1

Other Studies

2 other study(ies) available for 2-naphthoylglycine and sorbinil

ArticleYear
Relative structure-inhibition analyses of the N-benzoyl and N-(phenylsulfonyl) amino acid aldose reductase inhibitors.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:7

    Topics: Aldehyde Reductase; Amino Acids; Animals; Chemical Phenomena; Chemistry; Rats; Stereoisomerism; Structure-Activity Relationship

1991
Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: Aldehyde Reductase; Animals; Dose-Response Relationship, Drug; Molecular Conformation; Rats; Solubility; Structure-Activity Relationship; Sugar Alcohol Dehydrogenases

1989