Page last updated: 2024-08-18

2-naphthol and morphine

2-naphthol has been researched along with morphine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's2 (10.00)18.2507
2000's5 (25.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Duffy, EM; Jorgensen, WL1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Bock, KW; Brunner, G; Hoensch, H; Huber, E; Josting, D1
Götz, R; Schwarz, LR; Wiebel, FJ; Wolff, T1
Bock, KW; Lilienblum, W1
Bock, KW; Josting, D; Ottenwälder, H; von Clausbruch, UC1
Kharalambieva, M; Micheva, M; Raĭnova, L; Staneva-Stoĭcheva, D1
Bock, KW; Josting, D; Winne, D1
de Sandro, V; Ducrotoy, G; Kriszt, W; Lett, E; Richert, L1
Franklin, MR1
Franchi, M; Giuliani, L; Pacifici, GM; Rane, A1
Frankhuijzen-Sierevogel, AC; Koster, AS; Noordhoek, J1
Capel, ID; Millburn, P; Williams, RT1
Jeong, HJ; Lee, RH; Litman, DJ; Sizto, NC; Stiso, SN; Tom, HK; Ullman, EF1
Franklin, MR; Liu, Z1
Nakajima, M; Takemoto, K; Tanaka, Y; Yamazaki, H; Yokoi, T1
ONO, M; TAKAHASHI, K1
Eckstein, JA; Kasper, SC; Petullo, DM; Soars, MG; Wrighton, SA1
Borea, PA; Fazzi, D; Gessi, S; Merighi, S; Mirandola, P; Varani, K1

Reviews

1 review(s) available for 2-naphthol and morphine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

19 other study(ies) available for 2-naphthol and morphine

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Determination of microsomal UDP-glucuronyltransferase in needle-biopsy specimens of human liver.
    European journal of clinical pharmacology, 1978, Dec-18, Volume: 14, Issue:5

    Topics: Animals; Biopsy, Needle; Enzyme Induction; Glucuronosyltransferase; Humans; Kinetics; Microsomes, Liver; Morphine; Naphthols; Rats

1978
Monooxygenase and glucuronyltransferase activities in short term cultures of isolated rat hepatocytes.
    FEBS letters, 1979, Feb-01, Volume: 98, Issue:1

    Topics: Aldrin; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; Glucuronosyltransferase; In Vitro Techniques; Kinetics; Liver; Male; Morphine; Naphthols; Oxygenases; Rats

1979
Activation and induction of rat liver microsomal UDP-glucuronyltransferase with 6-hydroxybenzo(a)pyrene and N-hydroxy-2-naphthylamine as substrates.
    Biochemical pharmacology, 1979, Mar-01, Volume: 28, Issue:5

    Topics: 2-Naphthylamine; Animals; Benzopyrenes; Enzyme Activation; Enzyme Induction; Glucuronates; Glucuronosyltransferase; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Morphine; Naphthalenes; Naphthols; Rats

1979
Separation and partial purification of two differentially inducible UDP-glucuronyltransferases from rat liver.
    Biochemical pharmacology, 1977, Jun-01, Volume: 26, Issue:11

    Topics: Animals; Enzyme Induction; Glucuronosyltransferase; In Vitro Techniques; Methods; Methylcholanthrene; Microsomes, Liver; Morphine; Naphthols; Phenobarbital; Rats

1977
[Neurophoarmacologic profile of an aminotetraline derivative].
    Eksperimentalna meditsina i morfologiia, 1977, Volume: 16, Issue:4

    Topics: Amphetamine; Analgesics; Animals; Apomorphine; Central Nervous System; Drug Interactions; Hexobarbital; Mice; Morphine; Motor Activity; Muscle Tonus; Naphthols; Nervous System; Pentylenetetrazole; Piperazines; Rats; Reserpine; Strychnine

1977
Glucuronidation of paracetamol, morphine and 1-naphthol in the rat intestinal loop.
    Biochemical pharmacology, 1976, Mar-01, Volume: 25, Issue:5

    Topics: Acetaminophen; Animals; Enzyme Activation; Glucuronates; Glucuronosyltransferase; Intestinal Absorption; Intestinal Mucosa; Intestines; Jejunum; Microsomes; Microsomes, Liver; Morphine; Naphthols; Perfusion; Polyethylene Glycols; Rats; Time Factors; Uridine Diphosphate N-Acetylglucosamine

1976
Optimal detergent activation of rat liver microsomal UDP-glucuronosyl transferases toward morphine and 1-naphthol: contribution to induction and latency studies.
    Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7

    Topics: Animals; Detergents; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Naphthols; Phenobarbital; Rats; Rats, Inbred Strains

1992
Drug metabolizing enzyme induction by simple diaryl pyridines; 2-substituted isomers selectively increase only conjugation enzyme activities, 4-substituted isomers also induce cytochrome P450.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronosyltransferase; Liver; Male; Morphine; Naphthols; Nitrophenols; Pyridines; Rats; Rats, Inbred Strains; Stereoisomerism

1991
Development of the glucuronyltransferase and sulphotransferase towards 2-naphthol in human fetus.
    Developmental pharmacology and therapeutics, 1989, Volume: 14, Issue:2

    Topics: Adult; Fetus; Glucuronosyltransferase; Humans; Kinetics; Liver; Microsomes, Liver; Morphine; Naphthols; Sulfotransferases

1989
Distribution of glucuronidation capacity (1-naphthol and morphine) along the rat intestine.
    Biochemical pharmacology, 1985, Oct-01, Volume: 34, Issue:19

    Topics: Animals; Cecum; Colon; Duodenum; Glucuronates; Glucuronidase; Glucuronosyltransferase; Ileum; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Morphine; Naphthols; Rats; Rats, Inbred Strains; Rectum; Subcellular Fractions; Tissue Distribution; Uridine Diphosphate Glucose Dehydrogenase

1985
The conjugation of 1- and 2-naphthols and other phenols in the cat and pig.
    Xenobiotica; the fate of foreign compounds in biological systems, 1974, Volume: 4, Issue:10

    Topics: Amphetamine; Amphetamines; Animals; Carbon Radioisotopes; Cats; Chromatography, Paper; Chromatography, Thin Layer; Ephedrine; Female; Glucuronates; Glucuronidase; Indicators and Reagents; Isotope Labeling; Liver; Male; Morphine; Naphthols; Phenacetin; Phenolphthaleins; Phenols; Snails; Species Specificity; Sulfatases; Sulfuric Acids; Swine

1974
An internally referenced test strip immunoassay for morphine.
    Clinical chemistry, 1983, Volume: 29, Issue:9

    Topics: Antibodies; Glucose Oxidase; Horseradish Peroxidase; Humans; Immunoenzyme Techniques; Indicators and Reagents; Kinetics; Morphine; Naphthols; Reagent Strips; Reference Standards; Statistics as Topic; Temperature

1983
Separation of four glucuronides in a single sample by high-pressure liquid chromatography and its use in the determination of UDP glucuronosyltransferase activity toward four aglycones.
    Analytical biochemistry, 1984, Nov-01, Volume: 142, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Estrone; Glucuronates; Glucuronosyltransferase; Male; Microsomes, Liver; Morphine; Naphthols; Rats; Rats, Inbred Strains; Solvents; Substrate Specificity; Testosterone

1984
Catalytic activities of cytochrome P450 enzymes and UDP-glucuronosyltransferases involved in drug metabolism in rat everted sacs and intestinal microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Catalysis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Ethanolamines; Freezing; Glucuronides; Glucuronosyltransferase; Immunoblotting; Intestines; Male; Microsomes; Microsomes, Liver; Morphine; Naphthols; Nitrophenols; Oxidation-Reduction; Pharmaceutical Preparations; Rats; Rats, Wistar; Testosterone; Xenobiotics

2003
[COLORIMETRIC DETERMINATION OF MORPHINE BY MEANS OF ALPHA-NITROSO-BETA-NAPHTHOL].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1964, Volume: 82

    Topics: Colorimetry; Morphine; Naphthols; Nitroso Compounds

1964
An assessment of udp-glucuronosyltransferase induction using primary human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Cells, Cultured; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Estradiol; Female; Glucuronides; Glucuronosyltransferase; Hepatocytes; Humans; Hydroxytestosterones; Isoenzymes; Male; Mass Spectrometry; Middle Aged; Morphine; Naphthols; Propofol; Recombinant Proteins; Substrate Specificity

2004
Cannabinoid CB(2) receptor attenuates morphine-induced inflammatory responses in activated microglial cells.
    British journal of pharmacology, 2012, Volume: 166, Issue:8

    Topics: Animals; CHO Cells; Cricetinae; Cytokines; Gene Expression Regulation; Humans; Indoles; Inflammation; Lipopolysaccharides; MAP Kinase Kinase 1; Mice; Mice, Inbred BALB C; Microglia; Morphine; Naphthols; Nitric Oxide; Nitrites; Receptor, Cannabinoid, CB2; Receptors, Opioid, mu; RNA Interference; RNA, Small Interfering; Signal Transduction; Triazines

2012