Page last updated: 2024-08-18

2-naphthol and indomethacin

2-naphthol has been researched along with indomethacin in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's7 (36.84)18.2507
2000's6 (31.58)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Duffy, EM; Jorgensen, WL1
Caron, G; Ermondi, G1
Carrupt, PA; Martel, S; Ottaviani, G2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Asano, M; Hamada, K; Inamura, N; Isono, T; Kohsaka, M; Nagayoshi, A; Nakahara, K; Notsu, Y; Oku, T; Ono, T1
Hagihara, H; Mutoh, S; Nomoto, A; Ono, T; Yamaguchi, I1
Chiba, K; Goto, M; Hashida, R; Ono, H; Shirota, H1
Chiba, K; Goto, M; Shirota, H1
Ackerman, NR; Batt, DG; Bruin, EM; Collins, RJ; Harris, RR; Mackin, WM; Rakich, SM1
Morganroth, ML; Schoeneich, S; Till, GO; Ward, PA1
Sih, CJ; Takeguchi, C1
Goossens, J; Van Wauwe, J1
Hirose, R; Katori, M; Shishido, M; Tanaka, K1
de las Heras, B; Hoult, JR; Villar, A; Vivas, JM1
Chung, JH; Kim, JS; Lee, JY; Lim, KM1
Finel, M; Hirvonen, J; Kaukonen, AM; Laine, L; Siissalo, S; Tolonen, A1
Finel, M; Hirvonen, J; Rousu, T; Soikkeli, A; Tolonen, A; Zhang, H1

Reviews

1 review(s) available for 2-naphthol and indomethacin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

18 other study(ies) available for 2-naphthol and indomethacin

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
    Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13

    Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water

2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
A 5-lipoxygenase inhibitor, FR110302, suppresses airway hyperresponsiveness and lung eosinophilia induced by Sephadex particles in rats.
    Agents and actions, 1992, Volume: 36, Issue:3-4

    Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chromones; Dextrans; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Microspheres; Naphthols; Platelet Activating Factor; Prednisolone; Pulmonary Eosinophilia; Pyridines; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Thiazoles

1992
Role of inflammatory responses in initiation of atherosclerosis: effects of anti-inflammatory drugs on cuff-induced leukocyte accumulation and intimal thickening of rabbit carotid artery.
    Atherosclerosis, 1991, Volume: 91, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Arteriosclerosis; Carotid Arteries; Cell Adhesion; Cell Movement; Dexamethasone; Dose-Response Relationship, Drug; Endothelium, Vascular; Indomethacin; Inflammation; Male; Microscopy, Electron, Scanning; Naphthols; Neutrophils; Quinolines; Rabbits

1991
Antiinflammatory properties of E5090, a novel orally active inhibitor of IL-1 generation.
    Agents and actions. Supplements, 1991, Volume: 32

    Topics: Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Collagen; Edema; Fever; Indomethacin; Interleukin-1; Male; Naphthols; Pleurisy; Prednisolone; Rats; Rats, Inbred F344; Rats, Inbred Strains

1991
A novel inhibitor of IL-1 generation, E5090: in vivo inhibitory effect on the generation of IL-1-like factor and on granuloma formation in an air-pouch model.
    Agents and actions. Supplements, 1991, Volume: 32

    Topics: Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Exudates and Transudates; Granuloma; Indomethacin; Interleukin-1; Male; Naphthols; Orosomucoid; Prednisolone; Rats; Rats, Inbred F344

1991
Cellular and biochemical characterization of the anti-inflammatory effects of DuP 654 in the arachidonic acid murine skin inflammation model.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1990, Volume: 3, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chemotaxis; Dermatitis; Edema; Electron Spin Resonance Spectroscopy; Indomethacin; Leukocytes; Lipid Metabolism; Lipoxygenase Inhibitors; Male; Methadone; Mice; Naphthols; Peroxidase; Structure-Activity Relationship

1990
Eicosanoids are involved in the permeability changes but not the pulmonary hypertension after systemic activation of complement.
    Laboratory investigation; a journal of technical methods and pathology, 1988, Volume: 58, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Capillary Permeability; Chromatography, High Pressure Liquid; Complement Activation; Cyclooxygenase Inhibitors; Elapid Venoms; Hypertension, Pulmonary; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Male; Naphthols; Organ Culture Techniques; Rats; SRS-A; Thromboxane B2

1988
A rapid spectrophotometric assay for prostaglandin synthetase: application to the study of non-steroidal antiinflammatory agents.
    Prostaglandins, 1972, Volume: 2, Issue:3

    Topics: Adrenochrome; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Cattle; Cyclization; Fatty Acids, Unsaturated; Flufenamic Acid; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Indomethacin; Male; Mefenamic Acid; Multienzyme Complexes; Naphthols; Oxygenases; Phenylbutazone; Propionates; Prostaglandins; Seminal Vesicles; Spectrophotometry

1972
Effects of antioxidants on cyclooxygenase and lipoxygenase activities in intact human platelets: comparison with indomethacin and ETYA.
    Prostaglandins, 1983, Volume: 26, Issue:5

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Antioxidants; Blood Platelets; Catechols; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipoxygenase; Masoprocol; Naphthols; Propyl Gallate; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Quercetin

1983
Manipulation of thrombus formation in the hamster cheek pouch with drugs that interact with PGI2 in vitro.
    Prostaglandins, 1982, Volume: 23, Issue:6

    Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Epoprostenol; Indomethacin; Male; Mesocricetus; Microcirculation; Naphthols; Phthalazines; Platelet Aggregation; Prostaglandins

1982
Novel anti-inflammatory plant labdanes: comparison of in vitro properties with aspirin and indomethacin.
    Agents and actions, 1994, Volume: 41, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diterpenes; Eicosanoids; Humans; Indomethacin; Naphthols; Neutrophils; Phospholipases A; Phospholipases A2; Plant Extracts; Platelet Aggregation; Rats; Reactive Oxygen Species; Sodium Salicylate; Superoxides; Synovial Fluid; Terpenes

1994
Prostaglandin H synthase and lipoxygenase mediated activation of xenobiotics in platelets.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Aspirin; Biotransformation; Blood Platelets; Cyclooxygenase Inhibitors; Female; In Vitro Techniques; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Naphthols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Xenobiotics

1999
Caco-2 cell monolayers as a tool to study simultaneous phase II metabolism and metabolite efflux of indomethacin, paracetamol and 1-naphthol.
    International journal of pharmaceutics, 2010, Jan-04, Volume: 383, Issue:1-2

    Topics: Acetaminophen; Biological Transport; Caco-2 Cells; Humans; Indomethacin; Intestinal Absorption; Naphthols

2010
Highly variable pH effects on the interaction of diclofenac and indomethacin with human UDP-glucuronosyltransferases.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:8

    Topics: Anti-Inflammatory Agents; Diclofenac; Glucuronides; Glucuronosyltransferase; Humans; Hydrogen-Ion Concentration; Hymecromone; Indomethacin; Inhibitory Concentration 50; Naphthols

2012