Compounds > 2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene
Page last updated: 2024-09-03

2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene and nifedipine

2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene has been researched along with nifedipine in 4 studies

Compound Research Comparison

Studies
(2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene)		Trials
(2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene)		Recent Studies (post-2010)
(2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene)		Studies
(nifedipine)		Trials
(nifedipine)		Recent Studies (post-2010) (nifedipine)
140016,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomy2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coghlan, JP; Denton, DA; Hardy, KJ; Johnson, EI; McDougall, JG; Scoggins, BA; Wright, RD1
Rahwan, RG; Wong, WS1
Olah, ME; Rahwan, RG1
Heaslip, RJ; Rahwan, RG1

Other Studies

4 other study(ies) available for 2-n-propyl-3-dimethylamino-5,6-methylenedioxyindene and nifedipine

ArticleYear
Ca antagonists do not alter aldosterone secretion during established Na depletion.
    The American journal of physiology, 1985, Volume: 248, Issue:6 Pt 1

    Topics: Adrenal Glands; Aldosterone; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Edetic Acid; Female; Gallopamil; Hydrocortisone; Indenes; Ion Channels; Lanthanum; Nifedipine; Nisoldipine; Ryanodine; Sheep; Sodium; Verapamil

1985
Pharmacological actions of the calcium antagonist propyl-methylenedioxyindene in skinned vascular smooth muscle.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:8

    Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Indenes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Inbred Strains; Saponins; Trifluoperazine

1988
Age-related changes in responsiveness of the rat aorta to depolarizing and receptor-mediated contractile stimuli and to calcium antagonism.
    Pharmacology, 1987, Volume: 35, Issue:3

    Topics: Aging; Animals; Aorta; Calcium Channel Blockers; Indenes; Muscle Contraction; Nifedipine; Norepinephrine; Potassium; Rats; Rats, Inbred F344

1987
Norepinephrine-induced contractions of the rat aorta in the absence of extracellular calcium--II. Effects of calcium antagonists.
    General pharmacology, 1983, Volume: 14, Issue:5

    Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Culture Media; Dihydropyridines; In Vitro Techniques; Indenes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Verapamil

1983