Compounds > 2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene
Page last updated: 2024-09-03

2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene and verapamil

2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene has been researched along with verapamil in 2 studies

Compound Research Comparison

Studies
(2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene)		Trials
(2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene)		Recent Studies (post-2010)
(2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
100017,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomy2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Heaslip, RJ; Rahwan, RG1

Other Studies

2 other study(ies) available for 2-n-butyl-3-(dimethylamino)-5,6-methylenedioxyindene and verapamil

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Norepinephrine-induced contractions of the rat aorta in the absence of extracellular calcium--II. Effects of calcium antagonists.
    General pharmacology, 1983, Volume: 14, Issue:5

    Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Culture Media; Dihydropyridines; In Vitro Techniques; Indenes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Verapamil

1983