Page last updated: 2024-09-04

2-methylthio-n-6-isopentenyladenosine and adenosine

2-methylthio-n-6-isopentenyladenosine has been researched along with adenosine in 8 studies

Compound Research Comparison

Studies
(2-methylthio-n-6-isopentenyladenosine)
Trials
(2-methylthio-n-6-isopentenyladenosine)
Recent Studies (post-2010)
(2-methylthio-n-6-isopentenyladenosine)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
180532,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomy2-methylthio-n-6-isopentenyladenosine (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roe, BA; Wilson, RK1
Connolly, DM; Winkler, ME1
Elseviers, D; Petrullo, LA1
Adamiak, RW; Antkowiak, WS; Biała, E; Dembek, P; Swiderski, P1
Keith, DE; Longmire, ME; Vold, BS1
Elseviers, D; Gallagher, PJ; Petrullo, LA1
Buck, M; Griffiths, E1
Goddard, JP; Lowdon, M1

Other Studies

8 other study(ies) available for 2-methylthio-n-6-isopentenyladenosine and adenosine

ArticleYear
Presence of the hypermodified nucleotide N6-(delta 2-isopentenyl)-2-methylthioadenosine prevents codon misreading by Escherichia coli phenylalanyl-transfer RNA.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:2

    Topics: Adenosine; Amino Acid Sequence; Base Sequence; Chemical Fractionation; Chromatography, Thin Layer; Cloning, Molecular; Codon; Escherichia coli; Gene Expression Regulation; Isopentenyladenosine; Kinetics; Molecular Sequence Data; Phenylalanine-tRNA Ligase; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Phe; Transcription, Genetic

1989
Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12.
    Journal of bacteriology, 1989, Volume: 171, Issue:6

    Topics: 2-Aminopurine; Adenosine; Amino Acid Sequence; Base Sequence; Chromosome Mapping; Cloning, Molecular; DNA Mutational Analysis; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Iron; Isopentenyladenosine; Molecular Sequence Data; Mutation; Operon; Restriction Mapping; RNA, Transfer; Transcription, Genetic

1989
Effect of a 2-methylthio-N6-isopentenyladenosine deficiency on peptidyl-tRNA release in Escherichia coli.
    Journal of bacteriology, 1986, Volume: 165, Issue:2

    Topics: Adenosine; Cell-Free System; Escherichia coli; Isopentenyladenosine; Mutation; Protein Biosynthesis; Ribosomes; RNA, Transfer; RNA, Transfer, Amino Acyl

1986
Studies directed toward introduction of N6-isopentenyladenosine and its 2-methylthio analogue into oligoribonucleotides.
    Nucleic acids symposium series, 1987, Issue:18

    Topics: Adenosine; Indicators and Reagents; Isopentenyladenosine; Oligoribonucleotides

1987
Thiolation and 2-methylthio- modification of Bacillus subtilis transfer ribonucleic acids.
    Journal of bacteriology, 1981, Volume: 148, Issue:3

    Topics: Adenosine; Bacillus subtilis; Isopentenyladenosine; Purine Nucleosides; RNA, Bacterial; RNA, Transfer; Sulfides; Thionucleosides; Thiouridine; Threonine

1981
The role of 2-methylthio-N6-isopentenyladenosine in readthrough and suppression of nonsense codons in Escherichia coli.
    Molecular & general genetics : MGG, 1983, Volume: 190, Issue:2

    Topics: Adenosine; beta-Galactosidase; Codon; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation; Genes, Bacterial; Isopentenyladenosine; Mutation; Protein Biosynthesis; Ribosomal Protein S9; Ribosomal Proteins; Suppression, Genetic

1983
Regulation of aromatic amino acid transport by tRNA: role of 2-methylthio-N6-(delta2-isopentenyl)-adenosine.
    Nucleic acids research, 1981, Jan-24, Volume: 9, Issue:2

    Topics: Adenosine; Anticodon; Biological Transport; Escherichia coli; Isopentenyladenosine; Kinetics; Mutation; Phenylalanine; RNA, Transfer; Sulfides; Tryptophan; Tyrosine

1981
The effect upon aminoacylation of bisulphite addition to 2-methylthio-N6-isopentenyl adenosine of Escherichia coli phenylalanine tRNA.
    FEBS letters, 1981, Aug-03, Volume: 130, Issue:2

    Topics: Adenosine; Escherichia coli; Isopentenyladenosine; Nucleic Acid Conformation; RNA, Transfer, Amino Acyl; Sulfides; Sulfites; Transfer RNA Aminoacylation

1981