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2-methyl-4-chlorophenoxyacetic acid and 2-(4-chlorophenoxy)propionic acid

2-methyl-4-chlorophenoxyacetic acid has been researched along with 2-(4-chlorophenoxy)propionic acid in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's6 (31.58)18.2507
2000's8 (42.11)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bryant, SH; Conte Camerino, D; De Luca, A; Tortorella, V; Tricarico, D; Wagner, R1
Conte Camerino, D; De Luca, A; Tortorella, V1
Bryant, SH; Conte-Camerino, D; Heiny, JA; Jong, D; Tortorella, V1
Esbenshade, TA; Feller, DR; Kamanna, VS; Newman, HA; Tortorella, V; Witiak, DT1
Bettoni, G; Bryant, SH; Conte-Camerino, D; Feller, DR; Kamanna, VS; Loiodice, F; Newman, HA; Romstedt, KJ; Tortorella, V; Witiak, DT1
Bettoni, G; Bryant, SH; Conte-Camerino, D; Ferrannini, E; Loiodice, F; Mambrini, M; Tortorella, V1
Caldwell, J; Testa, B; van de Waterbeemd, H1
Camerino, C; Camerino, DC; Cocchi, D; De Luca, A; Pierno, S1
Aromataris, EC; Astill, DS; Bretag, AH; Bryant, SH; Roberts, ML; Rychkov, GY1
Accardi, A; Bertorello, L; Camerino, DC; De Luca, A; Liantonio, A; Pierno, S; Pusch, M; Tortorella, V1
Aromataris, EC; Bennetts, B; Bretag, AH; Hughes, BP; Roberts, ML; Rychkov, GY1
Accardi, A; Camerino, DC; Carbonara, G; De Luca, A; Fracchiolla, G; Guida, P; Liantonio, A; Loiodice, F; Pierno, S; Pusch, M; Tortorella, P; Traverso, S1
Antonio, L; Bonerba, E; Camerino, DC; De Luca, A; Didonna, MP; Elia, L; Fracchiolla, G; Liantonio, A; Loiodice, F; Picollo, A; Pierno, S; Pusch, M; Tortorella, P; Traverso, S1
Conte Camerino, D; De Luca, A; Fracchiolla, G; Guida, P; Liantonio, A; Loiodice, F; Picollo, A; Pierno, S; Pusch, M; Tortorella, P1
Camerino, DC; Didonna, MP; Elia, L; Liantonio, A; Picollo, A; Pusch, M1
Fong, P1
Babini, E; Murgia, AR; Picollo, A; Pusch, M; Zifarelli, G1
Kato, D; Negoro, S; Ohta, H; Takeo, M; Yoshida, H1
Albrechtsen, HJ; Bensch, HK; Bjerg, PL; Einsiedl, F; Elsner, M; Maier, MP; Milosevic, N; Qiu, S1

Reviews

2 review(s) available for 2-methyl-4-chlorophenoxyacetic acid and 2-(4-chlorophenoxy)propionic acid

ArticleYear
CLC-K channels: if the drug fits, use it.
    EMBO reports, 2004, Volume: 5, Issue:6

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Anion Transport Proteins; Chloride Channels; Humans; Membrane Proteins

2004
Channel or transporter? The CLC saga continues.
    Experimental physiology, 2006, Volume: 91, Issue:1

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Anthracenes; Antiporters; Binding Sites; Calcium Signaling; Chloride Channels; Chlorides; Humans; Ion Channel Gating; Membrane Transport Proteins; Multigene Family

2006

Other Studies

17 other study(ies) available for 2-methyl-4-chlorophenoxyacetic acid and 2-(4-chlorophenoxy)propionic acid

ArticleYear
Opposite effects of enantiomers of clofibric acid derivative on rat skeletal muscle chloride conductance: antagonism studies and theoretical modeling of two different receptor site interactions.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Binding Sites; Chloride Channels; Chlorides; Clofibric Acid; In Vitro Techniques; Kinetics; Male; Membrane Proteins; Models, Biological; Muscles; Rats; Rats, Inbred Strains; Stereoisomerism

1992
Chloride channels of skeletal muscle from developing, adult and aged rats are differently affected by enantiomers of 2-(p-chlorophenoxy) propionic acid.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:6

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Aging; Animals; Chloride Channels; Dose-Response Relationship, Drug; Membrane Potentials; Membrane Proteins; Muscle Development; Muscles; Rats; Rats, Wistar; Stereoisomerism

1992
Enantiomeric effects on excitation-contraction coupling in frog skeletal muscle by a chiral phenoxy carboxylic acid.
    Biophysical journal, 1990, Volume: 57, Issue:1

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Glycolates; In Vitro Techniques; Isomerism; Membrane Potentials; Muscle Contraction; Muscles; Rana catesbeiana; Structure-Activity Relationship

1990
In vivo and in vitro peroxisome proliferation properties of selected clofibrate analogues in the rat. Structure-activity relationships.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Acyl-CoA Oxidase; Animals; Body Weight; Cell Division; Cholesterol, Dietary; Clofibrate; Clofibric Acid; Glycolates; Male; Microbodies; Microsomes, Liver; Organ Size; Oxidoreductases; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship

1990
Dissociation of hypolipidemic and antiplatelet actions from adverse myotonic effects of clofibric acid related enantiomers.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Chlorides; Cholesterol; Clofibrate; Clofibric Acid; Electric Conductivity; Humans; Ion Channels; Male; Muscles; Platelet Aggregation; Rats; Stereoisomerism

1987
Stereospecificity of the chloride ion channel: the action of chiral clofibric acid analogues.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Cell Membrane; Chlorides; Clofibrate; Clofibric Acid; Ion Channels; Male; Muscles; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship

1987
The influence of conformational factors on the metabolic conjugation of aryloxyacetates.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:1

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Chemical Phenomena; Chemistry; Clofibric Acid; Glycolates; Inactivation, Metabolic; Models, Chemical; Molecular Conformation; Phenylacetates

1986
Higher content of insulin-like growth factor-I in dystrophic mdx mouse: potential role in the spontaneous regeneration through an electrophysiological investigation of muscle function.
    Neuromuscular disorders : NMD, 1999, Volume: 9, Issue:1

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Aging; Animals; Chloride Channels; Electrophysiology; Hindlimb; Insulin-Like Growth Factor I; Liver; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Dystrophy, Animal; Radioimmunoassay; Regeneration

1999
Modulation of the gating of CIC-1 by S-(-) 2-(4-chlorophenoxy) propionic acid.
    British journal of pharmacology, 1999, Volume: 126, Issue:6

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Cell Line; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Electric Stimulation; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Potentials; Muscle Proteins; Patch-Clamp Techniques; Rats; Stereoisomerism

1999
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives.
    Molecular pharmacology, 2000, Volume: 58, Issue:3

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Anticholesteremic Agents; Chloride Channels; Clofibric Acid; Humans; Male; Muscle, Skeletal; Mutation; Oocytes; Patch-Clamp Techniques; Rats; Rats, Wistar; Stereoisomerism; Torpedo; Transfection; Xenopus laevis

2000
Fast and slow gating of CLC-1: differential effects of 2-(4-chlorophenoxy) propionic acid and dominant negative mutations.
    Molecular pharmacology, 2001, Volume: 60, Issue:1

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Binding, Competitive; Cells, Cultured; Chloride Channels; Electrophysiology; Humans; Kinetics; Mutagenesis, Site-Directed

2001
Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.
    Molecular pharmacology, 2002, Volume: 62, Issue:2

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Anion Transport Proteins; Chloride Channels; CLC-2 Chloride Channels; Humans; Kidney; Male; Membrane Proteins; Muscle, Skeletal; Patch-Clamp Techniques; Rats; Recombinant Fusion Proteins; Structure-Activity Relationship; Transfection; Xenopus laevis; Xenopus Proteins

2002
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Binding Sites; Chloride Channels; Humans; Male; Muscle, Skeletal; Oocytes; Quantitative Structure-Activity Relationship; Rats; Rats, Wistar; Stereoisomerism; Xenopus laevis

2003
Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:1

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Animals; Chloride Channels; Electrophysiology; Humans; Kidney; Membrane Proteins; Rats; Structure-Activity Relationship; Xenopus laevis; Xenopus Proteins

2004
Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.
    EMBO reports, 2004, Volume: 5, Issue:6

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Motifs; Anion Transport Proteins; Binding Sites; Chloride Channels; Dose-Response Relationship, Drug; Humans; Membrane Proteins; Patch-Clamp Techniques; Point Mutation; Protein Structure, Tertiary

2004
Purification and gene cloning of an enantioselective thioesterification enzyme from Brevibacterium ketoglutamicum KU1073, a deracemization bacterium of 2-(4-chlorophenoxy)propanoic acid.
    Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:12

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Amino Acid Sequence; Brevibacterium; Cell-Free System; Cloning, Molecular; Coenzyme A Ligases; Enzyme Stability; Esterification; Molecular Sequence Data; Phenylpropionates; Recombinant Proteins; Sequence Analysis, DNA; Stereoisomerism; Substrate Specificity

2010
Combined isotope and enantiomer analysis to assess the fate of phenoxy acids in a heterogeneous geologic setting at an old landfill.
    Water research, 2013, Feb-01, Volume: 47, Issue:2

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Aluminum Silicates; Carbon Isotopes; Clay; Denmark; Deuterium; Environmental Monitoring; Fresh Water; Geologic Sediments; Groundwater; Halogenation; Herbicides; Models, Chemical; Oxygen Isotopes; Phenoxyacetates; Phenyl Ethers; Propionates; Rivers; Stereoisomerism; Water Pollutants, Chemical; Water Pollution, Chemical

2013