Page last updated: 2024-08-22

2-methoxytropolone and colchicine

2-methoxytropolone has been researched along with colchicine in 6 studies

*Colchicine: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). [MeSH]

*Colchicine: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's5 (83.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prakash, V; Timasheff, SN1
Andreu, JM; Gorbunoff, MJ; Medrano, FJ; Timasheff, SN1
Andreu, JM; Gorbunoff, MJ; Medrano, FJ; Rossi, M; Timasheff, SN1
Andreu, JM; Timasheff, SN1
D'Hoore, A; Dumortier, C; Engelborghs, Y; Fitzgerald, TJ; Vandecandelaere, A1
Chaudhuri, AR; LudueƱa, RF; Mizuhashi, F; Murata, K; Potenziano, JL; Tomita, I1

Other Studies

6 other study(ies) available for 2-methoxytropolone and colchicine

ArticleYear
Aging of tubulin at neutral pH: stabilization by colchicine and its analogues.
    Archives of biochemistry and biophysics, 1992, May-15, Volume: 295, Issue:1

    Topics: Animals; Brain Chemistry; Cattle; Circular Dichroism; Colchicine; Hydrogen-Ion Concentration; Protein Conformation; Spectrophotometry, Ultraviolet; Tropolone; Tubulin; Ultracentrifugation; Vincristine

1992
Roles of ring C oxygens in the binding of colchicine to tubulin.
    Biochemistry, 1991, Apr-16, Volume: 30, Issue:15

    Topics: Binding, Competitive; Biphenyl Compounds; Circular Dichroism; Colchicine; Kinetics; Ligands; Oxygen; Protein Conformation; Spectrometry, Fluorescence; Thermodynamics; Tropolone; Tubulin

1991
Mechanism of colchicine binding to tubulin. Tolerance of substituents in ring C' of biphenyl analogues.
    Biochemistry, 1991, Apr-16, Volume: 30, Issue:15

    Topics: Animals; Binding Sites; Biphenyl Compounds; Colchicine; GTP Phosphohydrolases; Hydrolysis; In Vitro Techniques; Kinetics; Ligands; Microtubules; Models, Molecular; Protein Conformation; Thermodynamics; Tropolone; Tubulin

1991
Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin.
    Biochemistry, 1982, Dec-07, Volume: 21, Issue:25

    Topics: Animals; Brain Chemistry; Cattle; Circular Dichroism; Colchicine; Cycloheptanes; Mathematics; Podophyllotoxin; Protein Conformation; Tropolone; Tubulin

1982
Evidence for an alternative pathway for colchicine binding to tubulin, based on the binding kinetics of the constituent rings.
    The Journal of biological chemistry, 1993, Jan-05, Volume: 268, Issue:1

    Topics: Acetophenones; Animals; Brain; Colchicine; Kinetics; Mathematics; Microtubules; Models, Theoretical; Protein Binding; Swine; Thermodynamics; Tropolone; Tubulin

1993
IKP104-induced decay of tubulin: role of the A-ring binding site of colchicine.
    Biochemistry, 1998, Dec-08, Volume: 37, Issue:49

    Topics: Alkylation; Animals; Benzaldehydes; Binding Sites; Cattle; Colchicine; Protein Conformation; Pyridones; Spectrometry, Fluorescence; Tropolone; Tubulin; Tubulin Modulators

1998