Page last updated: 2024-09-04

2-methoxystypandrone and naphthoquinones

2-methoxystypandrone has been researched along with naphthoquinones in 10 studies

Compound Research Comparison

Studies
(2-methoxystypandrone)
Trials
(2-methoxystypandrone)
Recent Studies (post-2010)
(2-methoxystypandrone)
Studies
(naphthoquinones)
Trials
(naphthoquinones)
Recent Studies (post-2010) (naphthoquinones)
120107,1101492,923

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's7 (70.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Cordingley, MG; Graham, PL; Reamer, RA; Singh, SB1
Chen, CC; Chiou, WF; Huang, CY; Liao, JF1
Chen, K; Chen, W; Kuang, S; Liu, J; Yu, Q; Zhang, Q1
Chen, CC; Chern, CM; Hou, YC; Liou, KT; Shen, YC; Wang, YH1
Kuang, S; Li, W; Liu, J; Qi, C; Sima, Z; Sun, X; Yu, Q; Zhang, Q1
Chowdhury, MMR; Khan, I; Kong, IK; Lee, KL; Mesalam, A; Park, KH; Song, SH; Uddin, Z1
Kuang, S; Li, W; Liu, J; Sima, Z; Song, Q; Yu, Q; Zhang, Q1
Chen, X; Gao, H; Kong, Q; Lu, JJ; Niu, Y; Yuan, R1
Cho, N; Lee, EW; Lee, J; Lee, JE; Li, A; Qiu, Y; Yoo, HM1
Ahmad, MS; Ahn, MJ; Ali, T; Haider, A; Khalil, AAK; Khan, MTA; Naeem, M; Nasir, A; Noor, R; Qazi, AS; Romman, M; Sajjad, W; Shah, FA; Shah, MA1

Reviews

1 review(s) available for 2-methoxystypandrone and naphthoquinones

ArticleYear
2-Methoxy-6-Acetyl-7-Methyljuglone: A Bioactive Phytochemical with Potential Pharmacological Activities.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:4

    Topics: Apoptosis; Humans; Hydrogen Peroxide; Naphthoquinones; Phytochemicals; Signal Transduction

2022

Other Studies

9 other study(ies) available for 2-methoxystypandrone and naphthoquinones

ArticleYear
Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues.
    Bioorganic & medicinal chemistry letters, 2001, Dec-17, Volume: 11, Issue:24

    Topics: 3C Viral Proteases; Cysteine Endopeptidases; Naphthoquinones; Protease Inhibitors; Structure-Activity Relationship; Viral Proteins

2001
2-Methoxystypandrone represses RANKL-mediated osteoclastogenesis by down-regulating formation of TRAF6-TAK1 signalling complexes.
    British journal of pharmacology, 2010, Volume: 161, Issue:2

    Topics: Animals; Bone Density Conservation Agents; Bone Resorption; Cell Differentiation; Cell Line; Down-Regulation; Drugs, Chinese Herbal; Fallopia japonica; Macrophages; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinases; Naphthoquinones; Osteoclasts; Protease Inhibitors; Protein Binding; RANK Ligand; Signal Transduction; TNF Receptor-Associated Factor 6

2010
Small-molecule STAT3 signaling pathway modulators from Polygonum cuspidatum.
    Planta medica, 2012, Volume: 78, Issue:14

    Topics: Anthraquinones; Apoptosis; Biological Assay; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Fallopia japonica; Female; Humans; Medicine, Chinese Traditional; Naphthoquinones; Phosphorylation; Plant Extracts; Plant Roots; Signal Transduction; STAT3 Transcription Factor

2012
2-Methoxystypandrone ameliorates brain function through preserving BBB integrity and promoting neurogenesis in mice with acute ischemic stroke.
    Biochemical pharmacology, 2014, Feb-01, Volume: 87, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; CD11b Antigen; Cyclooxygenase 2; Doublecortin Protein; Gene Expression Regulation; Immunologic Factors; Leukocytes; Male; Mice; Mice, Inbred ICR; Molecular Structure; Naphthoquinones; Neurogenesis; Nitric Oxide Synthase Type II; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stroke; Transcription Factor RelA

2014
2-Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor-κB signaling by inhibiting Janus kinase 2 and IκB kinase.
    Cancer science, 2014, Volume: 105, Issue:4

    Topics: Apoptosis; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; I-kappa B Kinase; Interleukin-6; Janus Kinase 2; Medicine, Chinese Traditional; Naphthoquinones; NF-kappa B; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha

2014
2-Methoxystypandrone improves in vitro-produced bovine embryo quality through inhibition of IKBKB.
    Theriogenology, 2017, Sep-01, Volume: 99

    Topics: Animals; Cattle; Embryo Culture Techniques; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; I-kappa B Kinase; Naphthoquinones; RNA, Messenger

2017
Synthesis of Biotinylated 2-methoxystypandrone and Identification of JAK2 and IKK as its Targets.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:3

    Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; I-kappa B Kinase; Janus Kinase 2; Molecular Structure; Naphthoquinones; Protein Kinase Inhibitors; Structure-Activity Relationship

2018
2-Methoxy-6-Acetyl-7-Methyljuglone (MAM) Induces iNOS/NO-mediated DNA Damage Response through Activation of MAPKs Pathways.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:6

    Topics: A549 Cells; Cell Proliferation; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Fallopia japonica; Humans; Mitogen-Activated Protein Kinases; Naphthoquinones; Nitric Oxide; Nitric Oxide Synthase Type II; Structure-Activity Relationship; Tumor Cells, Cultured

2018
Inhibition of Jurkat T Cell Proliferation by Active Components of
    Journal of microbiology and biotechnology, 2020, Dec-28, Volume: 30, Issue:12

    Topics: Anthraquinones; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cell Cycle; Cell Proliferation; Humans; Jurkat Cells; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Plant Extracts; Plant Roots; Reactive Oxygen Species; Republic of Korea; Rumex; Signal Transduction

2020