2-methoxyestradiol has been researched along with irc-110160 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agoston, GE; Hanson, AD; LaVallee, TM; Pribluda, V; Shah, JH; Suwandi, L; Treston, AM; Zhan, X | 1 |
| Agoston, GE; Burke, PA; Fogler, WE; Hamel, E; Hanson, AD; LaVallee, TM; Shah, J; Sidor, CF; Suwandi, L; Swartz, GM; Treston, AM | 1 |
| Camidge, DR; Diab, S; Eckhardt, SG; Gore, L; Gustafson, D; Leong, S; Lewis, K; Messersmith, WA; Nallapareddy, S; Sidor, C; Treston, AM; Zhou, Q | 1 |
| Kavallaris, M; Munoz, MA; Pasquier, E; Sinnappan, S | 1 |
1 trial(s) available for 2-methoxyestradiol and irc-110160
| Article | Year |
|---|---|
A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer.
Topics: 2-Methoxyestradiol; Administration, Oral; Adult; Aged; Animals; Antineoplastic Agents; Demography; Dogs; Dose-Response Relationship, Drug; Estradiol; Estrenes; Female; Humans; Male; Middle Aged; Neoplasms; Rats; Species Specificity | 2011 |
3 other study(ies) available for 2-methoxyestradiol and irc-110160
| Article | Year |
|---|---|
Synthesis, antiproliferative, and pharmacokinetic properties of 3- and 17-double-modified analogs of 2-methoxyestradiol.
Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Estradiol; Estrenes; Humans; Mice; Rats; Structure-Activity Relationship | 2009 |
Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198.
Topics: 2-Methoxyestradiol; Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Estradiol; Estrenes; G2 Phase; Hepatocytes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitory Concentration 50; Male; Mice; Mice, Inbred C57BL; Microtubules; Mitosis; Rats; Survival Analysis; Tubulin; Tubulin Modulators | 2008 |
ENMD-1198, a new analogue of 2-methoxyestradiol, displays both antiangiogenic and vascular-disrupting properties.
Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Blood Vessels; Cell Movement; Cell Proliferation; Cells, Cultured; Cytoskeleton; Drug Evaluation, Preclinical; Endothelial Cells; Estradiol; Estrenes; Humans; Male; Neovascularization, Pathologic; Neovascularization, Physiologic; Tubulin Modulators | 2010 |