Page last updated: 2024-08-24

2-methoxyestradiol and fosbretabulin

2-methoxyestradiol has been researched along with fosbretabulin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Dohle, W; Ferrandis, E; Hamel, E; Jourdan, F; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ1
Gangjee, A; Hamel, E; Lin, L; Mooberry, SL; Raghavan, S; Risinger, AL; Roberts, EG; Zhao, Y1
Bai, R; Dohle, W; Ferrandis, E; Hamel, E; Jourdan, F; Kimberley, MR; Leese, MP; Potter, BV; Thomas, MP1
Huang, J; Huang, L; Li, Y; Nie, H; Song, L; Wu, F1
D'Amato, RJ; Flynn, E; Hamel, E; Lin, CM1
Burnett, JC; Day, BW; Gussio, R; Hamel, E; Hermone, AR; McGrath, C; Nguyen, TL; Wipf, P; Zaharevitz, DW1

Other Studies

6 other study(ies) available for 2-methoxyestradiol and fosbretabulin

ArticleYear
Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.
    Journal of medicinal chemistry, 2010, Apr-08, Volume: 53, Issue:7

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Proliferation; Colchicine; Estradiol; Humans; Inhibitory Concentration 50; Protein Multimerization; Protein Structure, Quaternary; Structure-Activity Relationship; Tubulin

2010
Synthesis and discovery of water-soluble microtubule targeting agents that bind to the colchicine site on tubulin and circumvent Pgp mediated resistance.
    Journal of medicinal chemistry, 2010, Nov-25, Volume: 53, Issue:22

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cattle; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Protein Binding; Pyrimidines; Pyrroles; Solubility; Stereoisomerism; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Water

2010
Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.
    ACS medicinal chemistry letters, 2012, Jan-12, Volume: 3, Issue:1

    Topics:

2012
Design, synthesis and biological evaluation of combretastatin A-4 sulfamate derivatives as potential anti-cancer agents.
    RSC medicinal chemistry, 2021, Aug-18, Volume: 12, Issue:8

    Topics:

2021
Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubulin and with tubulin polymers.
    Biochemistry, 1996, Jan-30, Volume: 35, Issue:4

    Topics: 2-Methoxyestradiol; Binding Sites; Colchicine; Estradiol; Glutamates; Kinetics; Microtubule-Associated Proteins; Microtubules; Podophyllotoxin; Polymers; Stilbenes; Tubulin

1996
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach.
    Journal of medicinal chemistry, 2005, Sep-22, Volume: 48, Issue:19

    Topics: 2-Methoxyestradiol; 4-Butyrolactone; Aminophenols; Binding Sites; Chalcone; Colchicine; Cyclopropanes; Estradiol; Indans; Lignans; Models, Molecular; Molecular Structure; Nocodazole; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Sulfonamides; Thiazoles; Tubulin; Tubulin Modulators

2005