Page last updated: 2024-08-24

2-methoxyestradiol and cabozantinib

2-methoxyestradiol has been researched along with cabozantinib in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Dong, X; Jiang, H; Jiang, W; Jiang, X; Lin, H; Qiao, H; Sun, X; Zhu, H	1

Other Studies

2 other study(ies) available for 2-methoxyestradiol and cabozantinib

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
2ME2 inhibits the activated hypoxia-inducible pathways by cabozantinib and enhances its efficacy against medullary thyroid carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:1 Topics: 2-Methoxyestradiol; Active Transport, Cell Nucleus; Adult; Anilides; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Neuroendocrine; Cell Proliferation; Cell Survival; Estradiol; Female; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; Ki-67 Antigen; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pyridines; Signal Transduction; Thyroid Neoplasms; Xenograft Model Antitumor Assays	2016

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

2ME2 inhibits the activated hypoxia-inducible pathways by cabozantinib and enhances its efficacy against medullary thyroid carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:1

Topics: 2-Methoxyestradiol; Active Transport, Cell Nucleus; Adult; Anilides; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Neuroendocrine; Cell Proliferation; Cell Survival; Estradiol; Female; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; Ki-67 Antigen; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pyridines; Signal Transduction; Thyroid Neoplasms; Xenograft Model Antitumor Assays

2016