Page last updated: 2024-08-24

2-methoxyestradiol and bortezomib

2-methoxyestradiol has been researched along with bortezomib in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Anderson, KC; Auclair, D; Chauhan, D; Chen, LB; Hideshima, T; Li, G; Mitsiades, C; Mitsiades, N; Munshi, N; Podar, K; Saxena, S1
Fu, W; Hou, J; Jiang, H; Wang, D; Yuan, Z; Zhou, L1
Huang, HB; Lin, J; Wu, SQ; Xu, ZZ; Zhan, R1
Gu, JL; Huang, BH; Li, J; Liu, JR; Su, C; Zheng, D; Zhou, ZH1
Gartel, AL; Halasi, M; Hay, N; Nogueira, V; Pandit, B; Wang, M1
Han, J; Heo, HJ; Jeong, SH; Jeong, YJ; Kim, HK; Kim, N; Ko, KS; Ko, TH; Lee, SR; Rhee, BD; Song, IS; Youm, JB1

Other Studies

8 other study(ies) available for 2-methoxyestradiol and bortezomib

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
2-Methoxyestardiol and bortezomib/proteasome-inhibitor overcome dexamethasone-resistance in multiple myeloma cells by modulating Heat Shock Protein-27.
    Apoptosis : an international journal on programmed cell death, 2004, Volume: 9, Issue:2

    Topics: 2-Methoxyestradiol; Actins; Antineoplastic Agents; Boronic Acids; Bortezomib; Dexamethasone; Drug Resistance, Neoplasm; Estradiol; Heat-Shock Proteins; Humans; Multiple Myeloma; Peptides; Proteasome Inhibitors; Pyrazines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2004
Arsenic trioxide and 2-methoxyestradiol reduce beta-catenin accumulation after proteasome inhibition and enhance the sensitivity of myeloma cells to Bortezomib.
    Leukemia research, 2008, Volume: 32, Issue:11

    Topics: 2-Methoxyestradiol; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; beta Catenin; Blotting, Western; Boronic Acids; Bortezomib; Cell Proliferation; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Estradiol; Gene Expression Regulation, Neoplastic; Humans; Multiple Myeloma; Oxides; Proteasome Inhibitors; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured

2008
[Mechanism associated to enhancing the sensitivity of myeloma cells U266 to bortezomib by 2-methoxyestradiol].
    Zhongguo shi yan xue ye xue za zhi, 2011, Volume: 19, Issue:6

    Topics: 2-Methoxyestradiol; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Estradiol; Humans; Pyrazines

2011
Differentiation induction enhances bortezomib efficacy and overcomes drug resistance in multiple myeloma.
    Biochemical and biophysical research communications, 2012, Apr-13, Volume: 420, Issue:3

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Differentiation; DNA-Binding Proteins; Drug Resistance, Neoplasm; Estradiol; Humans; Multiple Myeloma; Pyrazines; Regulatory Factor X Transcription Factors; Transcription Factors; Tretinoin; Tumor Cells, Cultured; X-Box Binding Protein 1

2012
Combination of oxidative stress and FOXM1 inhibitors induces apoptosis in cancer cells and inhibits xenograft tumor growth.
    The American journal of pathology, 2013, Volume: 183, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Boronic Acids; Bortezomib; Cell Line, Tumor; Drug Administration Schedule; Estradiol; Female; Forkhead Box Protein M1; Forkhead Transcription Factors; Humans; Isothiocyanates; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Oxidative Stress; Pyrazines; Random Allocation; Reactive Oxygen Species; RNA Interference; Transplantation, Heterologous; Treatment Outcome

2013
Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells.
    Experimental & molecular medicine, 2013, Oct-25, Volume: 45

    Topics: 2-Methoxyestradiol; Acetylcysteine; Apoptosis; Boronic Acids; Bortezomib; Calcium; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Estradiol; Humans; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Pyrazines; Reactive Oxygen Species

2013