Page last updated: 2024-08-24

2-methoxyestradiol and acetylcysteine

2-methoxyestradiol has been researched along with acetylcysteine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Anderson, KC; Chauhan, D; Hideshima, T; Li, G; Mitsiades, C; Mitsiades, N; Munshi, N; Podar, K; Sattler, M1
Fujita, H; Inoue, A; Kanno, T; Muranaka, S; Tamai, H; Utsumi, K1
Aurilio, C; Chiefari, M; De Luca, B; Monda, M; Viggiano, A; Viggiano, D; Viggiano, E1
Gao, X; Irwin, MG; Liao, XL; Liu, Y; Mao, X; Ng, KF; Ou, JS; Vanhoutte, PM; Wang, T; Xia, Z; Xu, Y1
Han, J; Heo, HJ; Jeong, SH; Jeong, YJ; Kim, HK; Kim, N; Ko, KS; Ko, TH; Lee, SR; Rhee, BD; Song, IS; Youm, JB1
Joubert, AM; van den Bout, I; Visagie, MH1

Other Studies

10 other study(ies) available for 2-methoxyestradiol and acetylcysteine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Superoxide-dependent and -independent mitochondrial signaling during apoptosis in multiple myeloma cells.
    Oncogene, 2003, Sep-18, Volume: 22, Issue:40

    Topics: 2-Methoxyestradiol; Acetylcysteine; Antioxidants; Apoptosis; Complement Membrane Attack Complex; Complement System Proteins; Cytochrome c Group; Dexamethasone; Drug Resistance; Estradiol; Glycoproteins; Humans; Membrane Potentials; Mitochondria; Multiple Myeloma; Signal Transduction; Superoxides; Tumor Cells, Cultured

2003
Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: dependency on reactive oxygen species, Akt, Bid, cytochrome and caspase pathway.
    Free radical biology & medicine, 2004, Oct-15, Volume: 37, Issue:8

    Topics: 2-Methoxyestradiol; Acetylcysteine; Amino Acid Chloromethyl Ketones; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspases; Chromones; Cyclic AMP; Cyclosporine; Cysteine Proteinase Inhibitors; Cytochromes c; Diclofenac; DNA Fragmentation; DNA, Neoplasm; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Estradiol; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Morpholines; Oligopeptides; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase

2004
Trigeminal pain transmission requires reactive oxygen species production.
    Brain research, 2005, Jul-19, Volume: 1050, Issue:1-2

    Topics: 2-Methoxyestradiol; Acetylcysteine; Animals; Antioxidants; Enzyme Inhibitors; Estradiol; Facial Pain; Hydrogen Peroxide; Male; Microdialysis; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Trigeminal Nerve

2005
N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: 2-Methoxyestradiol; Acetylcysteine; Allopurinol; Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dinoprost; Drug Synergism; Echocardiography; Estradiol; Heme Oxygenase (Decyclizing); Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Isoprostanes; Male; Membrane Potential, Mitochondrial; Metalloporphyrins; Myocardial Reperfusion Injury; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Superoxide Dismutase

2013
Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells.
    Experimental & molecular medicine, 2013, Oct-25, Volume: 45

    Topics: 2-Methoxyestradiol; Acetylcysteine; Apoptosis; Boronic Acids; Bortezomib; Calcium; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Estradiol; Humans; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Pyrazines; Reactive Oxygen Species

2013
A bis-sulphamoylated estradiol derivative induces ROS-dependent cell cycle abnormalities and subsequent apoptosis.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: 2-Methoxyestradiol; Acetylcysteine; Apoptosis; Autophagy; Cell Line, Tumor; DNA Breaks, Double-Stranded; Estradiol; G2 Phase Cell Cycle Checkpoints; Histones; Humans; JNK Mitogen-Activated Protein Kinases; M Phase Cell Cycle Checkpoints; MCF-7 Cells; Membrane Potential, Mitochondrial; Oxidative Stress; Phosphorylation; Reactive Oxygen Species

2017