Compounds > 2-methoxyestradiol
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2-methoxyestradiol and 4-methoxyestradiol

2-methoxyestradiol has been researched along with 4-methoxyestradiol in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's3 (20.00)18.2507
2000's4 (26.67)29.6817
2010's6 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dutour, R; Poirier, D1
Davis, DL; Zhang, Z1
Chen, M; Chen, SH; Luo, GR; Wu, XS; Zhao, HM1
Daly, MJ; David, JS; Rajan, R; Reddy, VV; Reichle, F1
Antoniak, SK; Evaristus, EN; Liehr, JG; Ricci, MJ; Sarabia, SF; Zhu, BT1
Cao, JQ; Hayes, CL; Spink, BC; Spink, DC; Sutter, TR; Walker, NJ1
Dawling, S; Parl, FF; Roodi, N1
Sanderson, JT; van den Berg, M; van der Bruggen, M; van der Linden, J; van Duursen, MB1
Chang, LW; Chang, YC; Chen, CH; Cheng, YH; Lin, P; Yang, WJ1
Croxatto, HB; Cuevas, CA; Navarrete-Gómez, PA; Orihuela, PA; Parada-Bustamante, A; Ríos, M; Velasquez, LA; Villalón, MJ1
Amagai, T; Kuruto, R; Ohura, T; Sakakibara, H; Shimoi, K; Takemura, H; Uchiyama, H1
Dai, CF; Jobe, SO; Li, HH; Li, XF; Li, Y; Magness, RR; Patankar, MS; Yang, XS; Zhao, YJ; Zheng, J1
Brinton, LA; Dallal, CM; Falk, RT; Garcia-Closas, M; Gierach, GL; Hartman, TJ; Lissowska, J; Matthews, CE; Pfeiffer, RM; Veenstra, TD; Xu, X1
Anderson, GL; Arem, H; Brinton, LA; Cauley, JA; Chen, C; Coburn, SB; Falk, RT; Goodman, D; Matthews, CE; Oh, H; Pfeiffer, RM; Reding, KW; Trabert, B; Wentzensen, N; Xu, X1
Cardenas, H; Diaz, P; Godoy-Guzmán, C; Guajardo-Correa, E; Mena-Silva, D; Orihuela, PA1

Reviews

1 review(s) available for 2-methoxyestradiol and 4-methoxyestradiol

ArticleYear
Inhibitors of cytochrome P450 (CYP) 1B1.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship

2017

Other Studies

14 other study(ies) available for 2-methoxyestradiol and 4-methoxyestradiol

ArticleYear
Cell-type specific responses in prostaglandin secretion by glandular and stromal cells from pig endometrium treated with catecholestrogens, methoxyestrogens and progesterone.
    Prostaglandins, 1992, Volume: 44, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Endometrium; Estradiol; Estrogens, Catechol; Female; Pregnancy; Progesterone; Prostaglandins; Swine

1992
A new synthetic route to 2- and 4-methoxyestradiols by nucleophilic substitution.
    Steroids, 1986, Volume: 47, Issue:1

    Topics: 2-Methoxyestradiol; Chemical Phenomena; Chemistry; Estradiol

1986
Effects of catechol estrogen methyl ethers on lipid metabolism in prepubertal rats.
    Steroids, 1984, Volume: 43, Issue:5

    Topics: 2-Methoxyestradiol; Animals; Castration; Cholesterol; Cholesterol, Dietary; Estradiol; Estrogens, Catechol; Female; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Organ Size; Rats; Rats, Inbred Strains; Uterus

1984
Metabolic deglucuronidation and demethylation of estrogen conjugates as a source of parent estrogens and catecholestrogen metabolites in Syrian hamster kidney, a target organ of estrogen-induced tumorigenesis.
    Toxicology and applied pharmacology, 1996, Volume: 136, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Cell Fractionation; Cricetinae; Estradiol; Estrogens, Conjugated (USP); Estrone; Glucuronidase; Kidney; Kidney Neoplasms; Liver; Lysosomes; Male; Mesocricetus; Methylation; Oxidoreductases, N-Demethylating

1996
17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Sep-03, Volume: 93, Issue:18

    Topics: 2-Methoxyestradiol; Amino Acid Sequence; Base Sequence; Carbazoles; Catalysis; Cell Line; Cytochrome P-450 Enzyme System; DNA; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Indoles; Kinetics; Molecular Sequence Data; Saccharomyces cerevisiae

1996
Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1.
    Cancer research, 2003, Jun-15, Volume: 63, Issue:12

    Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Catechol O-Methyltransferase; Clinical Trials as Topic; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Deuterium; DNA Damage; Estradiol; Feedback, Physiological; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Methylation; Oxidation-Reduction; Recombinant Proteins

2003
Effects of several dioxin-like compounds on estrogen metabolism in the malignant MCF-7 and nontumorigenic MCF-10A human mammary epithelial cell lines.
    Toxicology and applied pharmacology, 2003, Aug-01, Volume: 190, Issue:3

    Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Benzofurans; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Line; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dioxins; Dose-Response Relationship, Drug; Epithelial Cells; Estradiol; Female; Humans; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins

2003
A comparative study on the effects of 2,3,7,8,-tetrachlorodibenzo-p-dioxin polychlorinated biphenyl126 and estrogen in human bronchial epithelial cells.
    Toxicology and applied pharmacology, 2004, Feb-15, Volume: 195, Issue:1

    Topics: 2-Methoxyestradiol; Bronchi; Cell Count; Cell Line; Cell Survival; Drug Synergism; Epithelial Cells; Estradiol; Humans; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins

2004
Catechol-o-methyltransferase and methoxyestradiols participate in the intraoviductal nongenomic pathway through which estradiol accelerates egg transport in cycling rats.
    Biology of reproduction, 2007, Volume: 77, Issue:6

    Topics: 2-Methoxyestradiol; Animals; Aryl Hydrocarbon Hydroxylases; Catechol O-Methyltransferase; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Egg Proteins; Estradiol; Estrogens, Catechol; Female; Gene Expression Regulation; Menstrual Cycle; Methylation; Oviducts; Ovum; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sexual Behavior, Animal

2007
A methoxyflavonoid, chrysoeriol, selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells.
    The Journal of steroid biochemistry and molecular biology, 2010, Volume: 118, Issue:1-2

    Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Biocatalysis; Breast Neoplasms; Carcinogens; Catechol O-Methyltransferase; Cell Line, Tumor; Chemoprevention; Culture Media, Conditioned; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Inhibitors; Estradiol; Estrogens, Catechol; Female; Flavones; Flavonoids; Gene Expression; Glucuronidase; Humans; Hydroxylation; Kinetics; Methylation; Oxazines; Recombinant Proteins; Sulfatases

2010
Estradiol 17β and its metabolites stimulate cell proliferation and antagonize ascorbic acid-suppressed cell proliferation in human ovarian cancer cells.
    Reproductive sciences (Thousand Oaks, Calif.), 2014, Volume: 21, Issue:1

    Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Catechol O-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Catechol; Female; Humans; Ovarian Neoplasms; Time Factors

2014
Association of Active and Sedentary Behaviors with Postmenopausal Estrogen Metabolism.
    Medicine and science in sports and exercise, 2016, Volume: 48, Issue:3

    Topics: 2-Methoxyestradiol; Accelerometry; Adult; Aged; Case-Control Studies; Estradiol; Estriol; Estrogens; Estrone; Exercise; Female; Humans; Middle Aged; Poland; Postmenopause; Sedentary Behavior

2016
Sitting, physical activity, and serum oestrogen metabolism in postmenopausal women: the Women's Health Initiative Observational Study.
    British journal of cancer, 2017, Sep-26, Volume: 117, Issue:7

    Topics: 2-Methoxyestradiol; Aged; Estradiol; Estrogens; Estrone; Exercise; Female; Hormone Replacement Therapy; Humans; Middle Aged; Postmenopause; Posture; Sedentary Behavior; Surveys and Questionnaires

2017
2-Methoxyoestradiol impairs mouse embryo implantation via F-spondin.
    Reproduction, fertility, and development, 2019, Volume: 31, Issue:4

    Topics: 2-Methoxyestradiol; Animals; Embryo Implantation; Estradiol; Extracellular Matrix Proteins; Female; Mice; Signal Transduction; Time Factors; Uterus

2019